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Listar Artículos (Química Orgánica) por autor "Sánchez Fernández, Elena Matilde"
Mostrando ítems 1-13 de 13
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Artículo
A selenoureido-iminoglycolipid transported by zeolitic-imidazolate framework nanoparticles: a novel antioxidant therapeutic approach
Guerrero, Fátima; Carmona, Andrés; Vidal, Victoria; Franco, Ana; Martín-Malo, Alejandro; Carrillo-Carrión, Carolina; Sánchez Fernández, Elena Matilde (Royal Society of Chemistry, 2023-10-05)A selenium-containing metal–organic framework with remarkable antioxidant capacity and ROS-scavenging activity was ...
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Anti-Inflammatory (M2) Response Is Induced by a sp2-Iminosugar Glycolipid Sulfoxide in Diabetic Retinopathy
Cano Cano, Fátima; Alcalde Estévez, Elena; Gómez Jaramillo, Laura; Iturregui, Marta; Sánchez Fernández, Elena Matilde; García Fernández, José Manuel; Ortiz Mellet, Carmen; Campos Caro, Antonio; López Tinoco, Cristina (Frontiers, 2021)Diabetic retinopathy (DR) is one of the most common complications of Diabetes Mellitus (DM) and is directly associated ...
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Fluoro-labelled sp2-iminoglycolipids with immunomodulatory properties
Padilla Pérez, María del Carmen; Sánchez Fernández, Elena Matilde; González-Bakker, Aday; Puerta, Adrián; Padrón, José M.; Martín-Loro, Francisco; García Fernández, José Manuel; Ortiz Mellet, Carmen (Elsevier, 2023)The unique electronic properties of the fluorine atom make its strategic incorporation into a bioactive compound a very ...
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Glycomimetic-based pharmacological chaperones for lysosomal storage disorders: lessons from Gaucher, GM1-gangliosidosis and Fabry diseases
Sánchez Fernández, Elena Matilde; García Fernández, José Manuel; Ortiz Mellet, Carmen (Royal Society of Chemistry, 2016)Lysosomal storage disorders (LSDs) are often caused by mutations that destabilize native folding and impair the trafficking ...
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New Castanospermine Glycoside Analogues Inhibit Breast Cancer Cell Proliferation and Induce Apoptosis without Affecting Normal Cells
Allan, Ghada; Ouadid-Ahidouch, Halima; Sánchez Fernández, Elena Matilde; Risquez Cuadrado, Rocío; García Fernández, José Manuel; Ortiz Mellet, Carmen; Ahidouch, Ahmed (Public Library of Science, 2013)sp2-Iminosugar-type castanospermine analogues have been shown to exhibit anti-tumor activity. However, their effects on ...
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Nuevas estrategias en el proceso de enseñanza-aprendizaje de la asignatura Experimentación Química II del Grado en Ingeniería Química Industrial
Sánchez Fernández, Elena Matilde (Universidad de Sevilla, 2018)El trabajo realizado durante el desarrollo del ciclo de mejora experimentado en la asignatura Experimentación en Química ...
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sp2-Iminosugar Glycolipids as Inhibitors of Lipopolysaccharide-mediated Human Dendritic Cell Activation in Vitro and of Acute Inflammation in Mice in Vivo
Schaeffer, Evelyne; Sánchez Fernández, Elena Matilde; Gonçalves-Pereira, Rita; Flacher, Vincent; Lamon, Delphine; Duval, Monique; Fauny, Jean Daniel; García Fernández, José Manuel; Mueller, Christopher G.; Ortiz Mellet, Carmen (Elsevier, 2019)Glycolipid mimetics consisting of a bicyclic polyhydroxypiperidine-cyclic carbamate core and a pseudoanomeric hydrophobic ...
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Speeding-up the Determination of Protein-Ligand Affinities by STD NMR: The Reduced Data Set STD NMR Approach (rd-STD NMR)
Rocha, Gabriel; Ramírez Cárdenas, Jonathan; Padilla Pérez, María del Carmen; Walpole, Samuel; Nepravishta, Ridvan; García Moreno, M. Isabel; Sánchez Fernández, Elena Matilde; Ortiz Mellet, Carmen; Angulo, Jesús; Muñoz García, Juan Carlos (American Chemical Society, 2024-01-02)STD NMR spectroscopy is a powerful ligand-observed NMR tool for screening and characterizing the interactions of small ...
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Stereoselective Synthesis of Iminosugar 2-Deoxy(thio)glycosides from Bicyclic Iminoglycal Carbamates Promoted by Cerium(IV) Ammonium Nitrate and Cooperative Brønsted Acid-Type Organocatalysis
Herrera González, Irene; Sánchez Fernández, Elena Matilde; Sau, Abhijit; Nativi, Cristina; Garciá Fernández, José M.; Galán, M. Carmen; Ortiz Mellet, Carmen (American Chemical Society, 2020)The first examples of iminosugar-type 2-deoxy(thio)glycoside mimetics are reported. The key step is the activation of a ...
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Synthesis of sp2-Iminosugar Selenoglycolipids as Multitarget Drug Candidates with Antiproliferative, Leishmanicidal and Anti-Inflammatory Properties
Sánchez Fernández, Elena Matilde; García Hernández, Raquel; Gamarro, Francisco; Arroba, Ana I.; Aguilar Diosdado, Manuel; Padrón, José M.; García Fernández, José Manuel; Ortiz Mellet, Carmen (Multidisciplinary Digital Publishing Institute (MDPI), 2021)sp2-Iminosugar glycolipids (sp2-IGLs) represent a consolidated family of glycoconjugate mimetics encompassing a ...
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Synthesis, conformational analysis and: In vivo assays of an anti-cancer vaccine that features an unnatural antigen based on an sp2-iminosugar fragment
Bermejo, Iris A; Navo, Claudio D.; Castro López, Jorge; Guerreiro, Ana; Jiménez Moreno, Ester; Sánchez Fernández, Elena Matilde; Ortiz Mellet, Carmen; Corzana, Francisco (Royal Society of Chemistry, 2020)The Tn antigen (GalNAc-α-1-O-Thr/Ser) is a well-known tumor-associated carbohydrate determinant. The use of glycopeptides ...
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Thiol-ene "Click" Synthesis and Pharmacological Evaluation of C-Glycoside sp2-Iminosugar Glycolipids
Sánchez Fernández, Elena Matilde; García Moreno, M. Isabel; García Hernández, Raquel; Padrón, José M.; García Fernández, José Manuel; Gamarro, Francisco; Ortiz Mellet, Carmen (MDPI, 2019)The unique stereoelectronic properties of sp2-iminosugars enable their participation in glycosylation reactions, thereby ...
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Unravelling the Inflammatory Processes in the Early Stages of Diabetic Nephropathy and the Potential Effect of (Ss)-DS-ONJ
Gómez Jaramillo, Laura; Cano Cano, Fátima; Sánchez Fernández, Elena Matilde; Ortiz Mellet, Carmen; García Fernández, José Manuel; Alcalá, Martín; Álvarez Gallego, Fabiola; Iturregui, Marta; González Montelongo, M. Carmen; Campos Caro, Antonio; Arroba, Ana I.; Aguilar Diosdado, Manuel (Multidisciplinary Digital Publishing Institute (MDPI), 2022)Inflammatory processes play a central role in the pathogenesis of diabetic nephropathy (DN) in the early stages of the ...