dc.creator | Calado, Sofía M. | es |
dc.creator | García Delgado, Ana Belén | es |
dc.creator | Cerda, Berta De la | es |
dc.creator | Ponte-Zuñiga, Beatriz | es |
dc.creator | Bhattacharya, Shomi S. | es |
dc.creator | Díaz Corrales, Francisco Javier | es |
dc.date.accessioned | 2019-01-16T10:43:14Z | |
dc.date.available | 2019-01-16T10:43:14Z | |
dc.date.issued | 2018-11-16 | |
dc.identifier.citation | Calado, S.M., García-Delgado, A.B., Cerda, B.D.l., Ponte-Zuñiga, B., Bhattacharya, S.S. y Díaz Corrales, F.J. (2018). Generation of a human iPS cell line from a patient with retinitis pigmentosa due to EYS mutation. Stem Cell Research, 33, 251-254. | |
dc.identifier.issn | 1873-5061 | es |
dc.identifier.uri | https://hdl.handle.net/11441/81617 | |
dc.description.abstract | Retinitis pigmentosa (RP) is an inherited retinal degenerative disease. Mutations in EYS have been associated with autosomal recessive RP. The human iPS cell line, CABi002-A, derived from peripheral blood mononuclear cells from a patient carrying a heterozygous double mutation in EYS gene was generated by non-integrative reprogramming technology, using hOCT3/4, hSOX2, hc-MYC and hKLF4 reprogramming factors. Pluripotency and differentiation capacity were assessed by immunocytochemistry and RT-PCR. This iPSC line can be further differentiated towards the affected cells to understand the pathophysiology of the disease and test new therapeutic strategies. | es |
dc.description.sponsorship | Cellex Foundation | es |
dc.description.sponsorship | Fundación Progreso y Salud | es |
dc.format | application/pdf | es |
dc.language.iso | eng | es |
dc.publisher | Elsevier | es |
dc.relation.ispartof | Stem Cell Research, 33, 251-254. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.title | Generation of a human iPS cell line from a patient with retinitis pigmentosa due to EYS mutation | es |
dc.type | info:eu-repo/semantics/article | es |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER) | es |
dc.relation.publisherversion | https://doi.org/10.1016/j.scr.2018.11.002 | es |
dc.identifier.doi | 10.1016/j.scr.2018.11.002 | es |
idus.format.extent | 4 p. | es |
dc.journaltitle | Stem Cell Research | es |
dc.publication.volumen | 33 | es |
dc.publication.initialPage | 251 | es |
dc.publication.endPage | 254 | es |
dc.contributor.funder | Cellex Foundation | |
dc.contributor.funder | Junta de Andalucía | |