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Artículo
Gene gating at nuclear pores prevents the formation of R loops
dc.creator | Gaillard, Hélène | es |
dc.creator | García Benítez, Francisco | es |
dc.creator | Aguilera López, Andrés | es |
dc.date.accessioned | 2018-08-30T08:10:00Z | |
dc.date.available | 2018-08-30T08:10:00Z | |
dc.date.issued | 2018 | |
dc.identifier.citation | Gaillard, H., García Benítez, F. y Aguilera López, A. (2018). Gene gating at nuclear pores prevents the formation of R loops. Molecular and Cellular Oncology, 5 (1), e1405140-. | |
dc.identifier.issn | 2372-3556 | es |
dc.identifier.uri | https://hdl.handle.net/11441/78285 | |
dc.description.abstract | Transcription is an important source of genetic variability. A large amount of transcription-associated genome variation arises from the unscheduled formation of R loops. We have recently found that physical proximity of chromatin to nuclear pores prevents the formation of pathological R loops during transcription. Our study opens new perspectives to understand genome stability as a function of nuclear location. | es |
dc.format | application/pdf | es |
dc.language.iso | eng | es |
dc.publisher | Taylor and Francis Ltd. | es |
dc.relation.ispartof | Molecular and Cellular Oncology, 5 (1), e1405140-. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Genome instability | es |
dc.subject | Genome organization | es |
dc.subject | Nuclear pores | es |
dc.subject | R loop | es |
dc.subject | Transcription | es |
dc.title | Gene gating at nuclear pores prevents the formation of R loops | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/submittedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Genética | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Ingeniería y Ciencia de los Materiales y del Transporte | |
dc.relation.publisherversion | http://dx.doi.org/10.1080/23723556.2017.1405140 | es |
dc.identifier.doi | 10.1080/23723556.2017.1405140 | es |
idus.format.extent | 6 p. | es |
dc.journaltitle | Molecular and Cellular Oncology | es |
dc.publication.volumen | 5 | es |
dc.publication.issue | 1 | es |
dc.publication.initialPage | e1405140 | es |
Ficheros | Tamaño | Formato | Ver | Descripción |
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Gene gating at nuclear pores.pdf | 75.98Kb | ![]() | Ver/ | |
Figure Gene gating at nuclear ... | 18.70Kb | ![]() | Ver/ | |