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Artículo
Evaluation of toxic effects induced by repeated exposure to Cylindrospermopsin in rats using a 28-day feeding study
(Elsevier, 2021-05)
Cylindrospermopsin (CYN) is a toxin with a world-wide increasing occurrence. It can induce toxic effects both in humans and the environment, and toxicity studies are needed to complete its toxicological profile. In this ...
Artículo
Cylindrospermopsin-microcystin-LR combinations may induce genotoxic and histopathological damage in rats
(Multidisciplinary Digital Publishing Institute (MDPI), 2020)
Cylindrospermopsin (CYN) and microcystins (MC) are cyanotoxins that can occur simultaneously in contaminated water and food. CYN/MC-LR mixtures previously investigated in vitro showed an induction of micronucleus (MN) ...
Artículo
Immunomodulatory Effects of Pure Cylindrospermopsin in Rats Orally Exposed for 28 Days
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)
Cylindrospermopsin (CYN) is a ubiquitous cyanotoxin showing increasing incidence worldwide. CYN has been classified as a cytotoxin and, among its toxic effects, its immunotoxicity is scarcely studied. This work investigates ...
Artículo
In vivo genotoxicity evaluation of cylindrospermopsin in rats using a combined micronucleus and comet assay
(Elsevier, 2019)
Cylindrospermopsin (CYN) is a potent cyanotoxin recognized as an emerging human threat due to its cytotoxicity and potential carcinogenicity. Although the genotoxicity of CYN has been extensively studied in vitro, limited ...