The RhoB small GTPase in physiology and disease

Vega Moreno, Francisco Manuel; Ridley, Anne J.

doi:10.1080/21541248.2016.1253528

Artículo

dc.creator	Vega Moreno, Francisco Manuel	es
dc.creator	Ridley, Anne J.	es
dc.date.accessioned	2023-10-23T12:41:20Z
dc.date.available	2023-10-23T12:41:20Z
dc.date.issued	2016-10-23
dc.identifier.citation	Vega Moreno, F.M. y Ridley, A.J. (2016). The RhoB small GTPase in physiology and disease. Small GTPases, 9 (5), 384-393. https://doi.org/10.1080/21541248.2016.1253528.
dc.identifier.issn	2154-1248	es
dc.identifier.uri	https://hdl.handle.net/11441/149843
dc.description.abstract	RhoB is a Rho family GTPase that is highly similar to RhoA and RhoC, yet has distinct functions in cells. Its unique C-terminal region is subject to specific post-translational modifications that confer different localization and functions to RhoB. Apart from the common role with RhoA and RhoC in actin organization and cell migration, RhoB is also implicated in a variety of other cellular processes including membrane trafficking, cell proliferation, DNA-repair and apoptosis. RhoB is not an essential gene in mice, but it is implicated in several physiological and pathological processes. Its multiple roles will be discussed in this review.	es
dc.format	application/pdf	es
dc.format.extent	11 p.	es
dc.language.iso	eng	es
dc.relation.ispartof	Small GTPases, 9 (5), 384-393.
dc.rights	Attribution-NonCommercial-NoDerivatives 4.0 Internacional	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/4.0/	*
dc.subject	Cancer progression	es
dc.subject	Development	es
dc.subject	Membrane	es
dc.subject	Trafficking	es
dc.subject	RhoB	es
dc.subject	Rho GTPases	es
dc.title	The RhoB small GTPase in physiology and disease	es
dc.type	info:eu-repo/semantics/article	es
dcterms.identifier	https://ror.org/03yxnpp24
dc.type.version	info:eu-repo/semantics/publishedVersion	es
dc.rights.accessRights	info:eu-repo/semantics/openAccess	es
dc.contributor.affiliation	Universidad de Sevilla. Departamento de Fisiología Médica y Biofísica	es
dc.relation.publisherversion	https://www.tandfonline.com/doi/full/10.1080/21541248.2016.1253528	es
dc.identifier.doi	10.1080/21541248.2016.1253528	es
dc.journaltitle	Small GTPases	es
dc.publication.volumen	9	es
dc.publication.issue	5	es
dc.publication.initialPage	384	es
dc.publication.endPage	393	es

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