Artículo
Editorial: Molecular Components of Store-Operated Calcium Entry in Health and Disease
Autor/es | Gruszczynska-Biegala, Joanna
Martín-Romero, Francisco Javier Smani Hajami, Tarik Secondo, Agnese |
Departamento | Universidad de Sevilla. Departamento de Fisiología Médica y Biofísica |
Fecha de publicación | 2021-10-05 |
Fecha de depósito | 2022-11-09 |
Publicado en |
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Resumen | Store-Operated Calcium Entry (SOCE) is a ubiquitous Ca2+ influx mechanism first described
in 1986 (Putney, 1986). This conserved mechanism results from the interaction between the
tetraspanning ORAI1 channel located in ... Store-Operated Calcium Entry (SOCE) is a ubiquitous Ca2+ influx mechanism first described in 1986 (Putney, 1986). This conserved mechanism results from the interaction between the tetraspanning ORAI1 channel located in plasma membrane and the unique endoplasmic reticulum (ER) Ca2+ sensor, stromal interaction molecule 1 (STIM1), via their respective intracellular domains (Roos et al., 2005; Csutora et al., 2008). Moreover, there are two homologs of ORAI1, namely ORAI2 and ORAI3, all generating SOCE with the same mechanism. |
Agencias financiadoras | Ministerio de Ciencia e Innovación (MICIN). España |
Identificador del proyecto | PID2019-104084GB-C22
AEI/10.13039/501100011033 |
Cita | Gruszczynska-Biegala J, Martin-Romero FJ, Smani T and Secondo A (2021) Editorial: Molecular Components of Store-Operated Calcium Entry in Health and Disease. Front. Cell. Neurosci. 15:771138. doi: 10.3389/fncel.2021.771138 |
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