dc.creator | Gonzalo Calvo, Gonzalo de | es |
dc.creator | Alcántara, Andrés R. | es |
dc.date.accessioned | 2022-10-19T17:24:39Z | |
dc.date.available | 2022-10-19T17:24:39Z | |
dc.date.issued | 2021 | |
dc.identifier.citation | Gonzalo Calvo, G.d. y Alcántara, A.R. (2021). Multienzymatic processes involving baeyer–villiger monooxygenases. Catalysts, 11 (5), 605. https://doi.org/10.3390/catal11050605. | |
dc.identifier.issn | 2073-4344 | es |
dc.identifier.uri | https://hdl.handle.net/11441/138144 | |
dc.description.abstract | Baeyer–Villiger monooxygenases (BVMOs) are flavin-dependent oxidative enzymes capable of catalyzing the insertion of an oxygen atom between a carbonylic Csp2 and the Csp3 at the alpha position, therefore transforming linear and cyclic ketones into esters and lactones. These enzymes are dependent on nicotinamides (NAD(P)H) for the flavin reduction and subsequent reaction with molecular oxygen. BVMOs can be included in cascade reactions, coupled to other redox enzymes, such as alcohol dehydrogenases (ADHs) or ene-reductases (EREDs), so that the direct conversion of alcohols or α,β-unsaturated carbonylic compounds to the corresponding esters can be achieved. In the present review, the different synthetic methodologies that have been performed by employing multienzymatic strategies with BVMOs combining whole cells or isolated enzymes, through sequential or parallel methods, are described, with the aim of highlighting the advantages of performing multienzymatic systems, and show the recent advances for overcoming the drawbacks of using BVMOs in these techniques. | es |
dc.description.sponsorship | Ministerio de Ciencia e Innovación PID2019-105337RB-C22 | es |
dc.description.sponsorship | Banco Santander-UCM PR87/19-22676 | es |
dc.format | application/pdf | es |
dc.format.extent | 25 p. | es |
dc.language.iso | eng | es |
dc.publisher | Multidisciplinary Digital Publishing Institute (MDPI) | es |
dc.relation.ispartof | Catalysts, 11 (5), 605. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Baeyer– Villiger alcohol dehydrogenases | es |
dc.subject | Biocatalysis | es |
dc.subject | Cascade reactions | es |
dc.subject | Ene-reductases | es |
dc.subject | Monooxygenases | es |
dc.subject | Redox enzymes | es |
dc.subject | Whole cells | es |
dc.title | Multienzymatic processes involving baeyer–villiger monooxygenases | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Química orgánica | es |
dc.relation.projectID | PID2019-105337RB-C22 | es |
dc.relation.projectID | PR87/19-22676 | es |
dc.relation.publisherversion | https://doi.org/10.3390/catal11050605 | es |
dc.identifier.doi | 10.3390/catal11050605 | es |
dc.journaltitle | Catalysts | es |
dc.publication.volumen | 11 | es |
dc.publication.issue | 5 | es |
dc.publication.initialPage | 605 | es |
dc.contributor.funder | Ministerio de Ciencia e Innovación (MICIN). España | es |
dc.contributor.funder | Banco Santander-UCM | es |