Química Orgánica y Farmacéutica
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PhD Thesis
Determinación de grasa trans en productos alimentarios en España por aplicación de la espectrofotometría infrarroja por transformadas de Fourier y reflexión total atenuada de segunda derivada (ART-FTIR (-2D))
(2024-05-31)Los ácidos grasos trans son más perjudiciales desde el punto de vista nutricional que los ácidos grasos saturados. Una ...
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Article
Homochiral imidazolium-based dicarboxylate silver(i) compounds: synthesis, characterisation and antimicrobial properties
(Royal Society of Chemistry, 2022-03)Complexes [Ag(LR)], 2 (LR = 2,2′-(imidazolium-1,3-diyl)di(2-alkylacetate)), were prepared by treatment of compounds HLR, ...
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Article
Experimental model design: exploration and optimization of customized polymerization conditions for the preparation of targeted smart materials by the Diels Alder click reaction
(Royal Society of Chemistry, 2019)The experimental model design proposed herein has proved to be an indispensable tool to rapidly and easily elucidate the ...
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Article
Design and manufacturing by fused filament technique of novel YSZ porous grafts infiltrated with PCL/PVA/AgNPs for large bone defects repairing
(Elsevier, 2024-02-19)Addressing large bone segmental defects remains a profound challenge in orthopaedic surgery, demanding graft designs that ...
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Patent. Invention
Compuestos derivados de sulforafano, método de obtención y su uso médico, alimenticio y cosmético
(Oficina Española de Patentes y Marcas (OEPM)., 2014)Compuestos derivados de sulforafano, método de obtención y su uso médico, alimenticio y cosméticoLa presente invención ...
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Article
Biodegradable double cross-linked chitosan hydrogels for drug delivery: Impact of chemistry on rheological and pharmacological performance
(Elsevier, 2020-12)This study investigates the impact of dual ionic and covalent cross-links (ion-XrL and cov-XrL) on the properties of ...
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Article
Metabolites and tissue distribution of resveratrol in the pig
(Wiley-Blackwell, 2011-08)Scope: trans-Resveratrol (RES) and/(or) its metabolites exert many effects in vivo. Our aim was to study the metabolism ...
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Article
Chiral sulfur derivatives in the allylation of acyl hydrazones: C 2-symmetric bis-sulfinamides as enhanced chiral organic promoters
(Royal Society of Chemistry, 2010-10)Monosulfinamides and C2-symmetric bis-sulfinamides are convenient neutral chiral promoters in the allylation of acyl ...
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Article
DMAP-Catalysed Sulfinylation of Diacetone-D-Glucose: Improved Method for the Synthesis of Enantiopure tert-Butyl Sulfoxides and tert-Butanesulfinamide
(Wiley Online Library, 2014-11)An improved method for the tert-butanesulfinylation of diacetone glucose with tert-butanesulfinyl chloride is reported. ...
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Article
An Efficient and Practical Method for the Enantioselective Synthesis of Tertiary Trifluoromethyl Carbinols
(Wiley Online Library, 2018-03)An efficient sulfinamide/olefin based chiral ligand, MetSulfolefin, has been developed for the enantioselective rhodium-catalysed ...
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Article
Sulfinamide Phosphinates as Chiral Catalysts for the Enantioselective Organocatalytic Reduction of Imines
(American Chemical Society, 2016-07)A new type of chiral sulfinamide phosphinate catalysts with up to three stereogenic centers, readily accessible from ...
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Article
Preventive oral treatment with resveratrol pro-prodrugs drastically reduce colon inflammation in rodents
(American Chemical Society, 2010-10-28)There is no pharmaceutical or definitive surgical cure for inflammatory bowel diseases (IBDs). The naturally occurring ...
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Article
Tandem ATRP/Diels-Alder Synthesis of PolyHEMA-based Hydrogels
(Royal Society of Chemistry, 2014)The efficient, controlled polymerization of a batch of new poly(hydroxyethyl methacrylate-co-furfuryl methacrylate)s, ...
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Article
Resveratrol and some glucosyl, glucosylacyl, and glucuronide derivatives reduce Escherichia coli O157:H7, Salmonella typhimurium, and Listeria monocytogenes Scott A adhesion to colonic epithelial cell lines
(American Chemical Society, 2012)The efficacy of resveratrol and some glucosyl, glucosylacyl, and glucuronide derivatives in inhibiting the adhesion of ...
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Article
Identifying Coordination Geometries of Metal Aquaions in Water: Application to the Case of Lanthanoid and Actinoid Hydrates
(American Chemical Society, 2016)The angular distribution function (ADF) associated with the oxygen-metal ion-oxygen angle (OMO) of several trivalent ...
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Article
Synthetic Polymers from Sugar-Based Monomers
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Article
Solving the Hydration Structure of the Heaviest Actinide Aqua IonKnown: The Californium(III) Case
(Wiley-Blackwell, 2010)Wish they all could be californium: X-ray absorption spectroscopy (black points) and Monte Carlo simulations (blue line) ...
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Article
The Gut Microbiota Ellagic Acid-Derived Metabolite Urolithin A and Its Sulfate Conjugate Are Substrates for the Drug Efflux Transporter Breast Cancer Resistance Protein (ABCG2/BCRP)
(American Chemical Society, 2013)The breast cancer resistance protein (BCRP/ABCG2) is a drug efflux transporter that can affect the pharmacological and ...
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Article
Neuroprotective and Anti-inflammatory Effects of Pterostilbene Metabolites in Human Neuroblastoma SH-SY5Y and RAW 264.7 Macrophage Cells
(American Chemical Society, 2020)Oxidative stress is known to be a key factor in many neurodegenerative diseases. Inflammation also plays a relevant role ...