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Mostrando ítems 1-10 de 19
Artículo
Preventive oral treatment with resveratrol pro-prodrugs drastically reduce colon inflammation in rodents
(American Chemical Society, 2010-10-28)
There is no pharmaceutical or definitive surgical cure for inflammatory bowel diseases (IBDs). The naturally occurring polyphenol resveratrol exerts anti-inflammatory properties. However, its rapid metabolism diminishes ...
Artículo
Repurposing Study of 4-Acyl-1-phenylaminocarbonyl-2-substituted-piperazine Derivatives as Potential Anticancer Agents-In Vitro Evaluation against Breast Cancer Cells
(MDPI, 2023)
first_pagesettingsOrder Article Reprints Open AccessArticle Repurposing Study of 4-Acyl-1-phenylaminocarbonyl-2-substituted-piperazine Derivatives as Potential Anticancer Agents—In Vitro Evaluation against Breast Cancer ...
Artículo
Metabolites and tissue distribution of resveratrol in the pig
(Wiley-Blackwell, 2011-08)
Scope: trans-Resveratrol (RES) and/(or) its metabolites exert many effects in vivo. Our aim was to study the metabolism and tissue distribution of RES using the pig, a mammal physiologically close to humans. Methods and ...
Artículo
Passive targeting of high-grade gliomas via the EPR effect: a closed path for metallic nanoparticles?
(Royal Society of Chemistry, 2021-10-28)
Passive tumor targeting via the enhanced permeability and retention (EPR) effect has long been considered the most effective mechanism for the accumulation of nanoparticles inside solid tumors. However, several studies ...
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Artículo
Biologically Relevant Micellar Nanocarrier Systems for Drug Encapsulation and Functionalization of Metallic Nanoparticles
(MDPI, 2022)
The preparation of new and functional nanostructures has received more attention in the scientific community in the past decade due to their wide application versatility. Among these nanostructures, micelles appear to be ...
Artículo
Inhibition of Endothelial Inflammatory Response by HT-C6, a Hydroxytyrosol Alkyl Ether Derivative
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)
Hydroxytyrosol (HT) is a bioactive phenolic compound naturally present in olives and extra virgin olive oil (EVOO) which is described as an antioxidant, antitumoral and antiangiogenic molecule. Previous studies of ...
Artículo
Synthesis and Characterization of New Carbohydrate-based Polyureas
(Tech Science Press, 2013-07)
A batch of linear [m,n]-type sugar-based polyureas was synthesized by polyaddition reaction in solution from hexamethylene diisocyanate or 4,4’-methylene-bis(phenyl isocyanate) with the acyclic 2,3,4-tri-O-methyl-1,5- ...
Artículo
Collecting high-order interactions in an effective pairwise intermolecular potential using the hydrated ion concept: The hydration of Cf3+
(American Institute of Physics Publising LLC, 2014)
This work proposes a new methodology to build interaction potentials between a highly charged metal cation and water molecules. These potentials, which can be used in classical computer simu- lations, have been fitted to ...
Artículo
Molecular bottom-up approaches for the synthesis of inorganic and hybrid nanostructures
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
Chemical routes for the synthesis of nanostructures are fundamental in nanoscience. Among the different strategies for the production of nanostructures, this article reviews the fundamentals of the bottom-up approaches, ...