Listar Artículos (Fisiología Médica y Biofísica) por título
Mostrando ítems 304-323 de 325
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The systemic administration of oleoylethanolamide exerts neuroprotection of the nigrostriatal system in experimental Parkinsonism
(CINP, 2013)Oleoylethanolamide (OEA) is an agonist of the peroxisome proliferator-activated receptor α (PPARα) and has been described ...
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Theranostics in boron neutron capture therapy
(MDPI, 2021-04-10)Boron neutron capture therapy (BNCT) has the potential to specifically destroy tumor cells without damaging the tissues ...
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Thyrotropin-releasing-hormone (TRH) and its physiological metabolite TRH-OH inhibit Na+ channel activity in mammalian septal neurons
(1990)The interaction of thyrotropin-releasing hormone (TRH) and its physiological metabolite TRH-OH with Na+ channels was studied ...
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Toward a New Paradigm in Resistance Training by Means of Velocity Monitoring: A Critical and Challenging Narrative
(Springer, 2022-09-16)For more than a century, many concepts and several theories and principles pertaining to the goals, organization, methodology ...
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Transcriptomic analysis reveals an association of FCGBP with Parkinson’s disease
(Nature Research, 2022-11-12)Transcriptomics in Parkinson’s disease (PD) offers new insights into the molecular mechanism of PD pathogenesis. Several ...
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Transcriptomic and cellular decoding of regional brain vulnerability to neurogenetic disorders
(Nature Portfolio, 2020)Neurodevelopmental disorders have a heritable component and are associated with region specific alterations in brain ...
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Transcriptomic and connectomic correlates of differential spatial patterning among gliomas
(Oxford University Press, 2022-10-18)Unravelling the complex events driving grade-specific spatial distribution of brain tumour occurrence requires rich datasets ...
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Transgenic NADH dehydrogenase restores oxygen regulation of breathing in mitochondrial complex I-deficient mice
(NATURE PUBLISHING GROUP, 2023)The hypoxic ventilatory response (HVR) is a life-saving reflex, triggered by the activation of chemoreceptor glomus cells ...
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Trasplante de células naturales "dopaminotróficas" nuevo concepto terapeútico antiparkinsoniano
(Viguera, 2003)Aim and method. Parkinson's disease is caused by the degeneration of dopamineric neurons of substantia nigra projecting ...
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Treatment with trkC agonist antibodies delays disease progression in neuromuscular degeneration (nmd) mice
(OXFORD UNIV PRESS, 2005)Spinal muscular atrophy with respiratory distress type 1 (SMARD1) is a fatal autosomal recessive disorder seen in infants. ...
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Trophic restoration of the nigrostriatal dopaminergic pathway in long-term carotid body-grafted parkinsonian rats
(2003)We studied the mechanisms underlying long-term functional recovery of hemiparkinsonian rats grafted intrastriatally with ...
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TRPC and TRPV Channels’ Role in Vascular Remodeling and Disease
(doi:10.3390/ijms21176125, 2020-08-25)Transient receptor potentials (TRPs) are non-selective cation channels that are widely expressed in vascular beds. They ...
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TRPC Channels in the SOCE Scenario
(MDPI, 2020)Transient receptor potential (TRP) proteins form non-selective Ca2+ permeable channels that contribute to the modulation ...
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TRPC6 channels are required for proliferation, migration and invasion of breast cancer cell lines by modulation of Orai1 and Orai3 surface exposure
(MDPI AC, 2018-09-14)Transient receptor potential channels convey signaling information from a number of stimuli to a wide variety of cellular ...
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Two for the Price of One: A Neuroprotective Chaperone Kit within NAD Synthase Protein NMNAT2
(Public Library of Science, 2016-07-25)One of the most fascinating properties of the brain is the ability to function smoothly across decades of a lifespan. ...
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Unexpected obesity, rather than tumorigenesis, in a conditional mouse model of mitochondrial complex II deficiency
(Federation amer soc exp biol, 2021)Mutations in any of the genes encoding the four subunits of succinate dehydrogenase (SDH), a mitochondrial membrane-bound ...
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Upregulation of CD38 expression on multiple myeloma cells by novel HDAC6 inhibitors is a class effect and augments the efficacy of daratumumab
(Nature Publishing Group, 2021)Multiple myeloma (MM) is incurable, so there is a significant unmet need for effective therapy for patients with relapsed ...
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Urocortin Role in Ischemia Cardioprotection and the Adverse Cardiac Remodeling
(MDPI, 2021-11-09)Despite the considerable progress in strategies of myocardial protection, ischemic heart diseases (IHD) and consequent ...
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Urocortin-1 Mediated Cardioprotection Involves XIAP and CD40-Ligand Recovery Role of EPAC2 and ERK12
(Public Library of Science, 2016)Urocortin-1 (Ucn-1) is an endogenous peptide that protects heart from ischemia and reperfusion (I/R) injuries. Ucn-1 is ...
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Urocortin-2 Prevents Dysregulation of Ca2+ Homeostasis and Improves Early Cardiac Remodeling After Ischemia and Reperfusion
(Frontiers Research Foundation, 2018-07-03)Aims: Urocortin-2 (Ucn-2) is a potent cardioprotector against Ischemia and Reperfusion (I/R) injuries. However, little is ...