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Listar Artículos (Fisiología Médica y Biofísica) por autor "López Barneo, José"
Mostrando ítems 41-60 de 70
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Multiple Facets of Maxi-K Channels: The Heme Connection
López Barneo, José; Castellano Orozco, Antonio Gonzalo (2005) -
Artículo
Neurotransmitter Modulation of Carotid Body Germinal Niche
Sobrino, Verónica; Platero-Luengo, Aida; Annese, Valentina; Navarro Guerrero, Elena; González Rodríguez, Patricia; López Barneo, José; Pardal Redondo, Ricardo (MDPI AG, 2020-11-03)The carotid body (CB), a neural-crest-derived organ and the main arterial chemoreceptor in mammals, is composed of clusters ...
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Oxygen regulation of breathing is abolished in mitochondrial complex III-deficient arterial chemoreceptors
Cabello Rivera, Daniel; Ortega Sáenz, Patricia; Gao Chen, Lin; Muñoz Cabello, Ana María; Bonilla-Henao, Victoria; Schumacker, Paul T.; López Barneo, José (National Academy of Sciences, 2022)Acute oxygen (O2) sensing is essential for adaptation of organisms to hypoxic environments or medical conditions with ...
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Oxygen sensing by ion channels and chemotransduction in single glomus cells
López Barneo, José; Montoro Laseca, Rafael Jesús; Ureña López, Juan; Fernández-Chacón, Rafael; Álvarez de Toledo Naranjo, Guillermo (1996)We have monitored cytosolic [Ca2+] and dopamine release in intact fura-2-loaded glomus cells with microfluoroimetry and a ...
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Oxygen-sensitive calcium channels in vascular smooth muscle and their possible role in hypoxic arterial relaxation
Franco Obregón, Alfredo; Ureña López, Juan; López Barneo, José (1995)We have investigated the modifications of cytosolic [Ca2+] and the activity of Ca2+ channels in freshly dispersed arterial ...
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Potassium Channel Types in Arterial Chemoreceptor Cells and Their Selective Modulation by Oxygen
Ganfornina, María Dolores; López Barneo, José (1992)Single K+ channel currents were recorded in excised membrane patches from dispersed chemoreceptor cells of the rabbit ...
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Prolyl Hydroxylase-dependent Modulation of Eukaryotic Elongation Factor 2 Activity and Protein Translation under Acute Hypoxia
Romero-Ruiz, Antonio; Bautista, Lucía; Navarro, Virginia; Heras Garvín, Antonio; Castellano Orozco, Antonio Gonzalo; López Barneo, José; Pascual, Alberto (American Society for Biochemistry and Molecular Biology, 2012-02-03)Early adaptive responses to hypoxia are essential for cell survival, but their nature and underlying mechanisms are poorly ...
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Properties of Calcium and Potassium Currents of Clonal Adrenocortical Cells
López Barneo, José; Tabares, Lucía; Ureña López, Juan (1989)The ionic currents of clonal Y-1 adrenocortical cells were studied using the whole-cell variant of the patch-clamp technique. ...
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Protection and repair of the nigrostriatal pathway with stem-cell-derived carotid body glomus cell transplants in chronic MPTP Parkinsonian model
Villadiego Luque, Francisco Javier; Muñoz-Manchado, Ana B.; Sobrino Cabello, Verónica; Bonilla-Henao, Victoria; Suárez-Luna, Nela; Ortega Sáenz, Patricia; Pardal Redondo, Ricardo; López Barneo, José; Toledo Aral, Juan José (MDPI, 2023-03-14)Antiparkinsonian carotid body (CB) cell therapy has been proven to be effective in rodent and nonhuman primate models of ...
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¿Qué nos enseñan los modelos animales y celulares sobre la enfermedad de Parkinson?
López Barneo, José (2013) -
Artículo
Rat Adrenal Chromaffin Cells Are Neonatal CO2 Sensors
Muñoz Cabello, Ana María; Toledo Aral, Juan José; López Barneo, José; Echevarría Irusta, Miriam (2005)We studied the participation of adrenal medulla (AM) chromaffin cells in hypercapnic chemotransduction. Using amperometric ...
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Redox signaling in acute oxygen sensing
Gao Chen, Lin; González Rodríguez, Patricia; Ortega Sáenz, Patricia; López Barneo, José (Elsevier, 2017-04-26)Acute oxygen (O2) sensing is essential for individuals to survive under hypoxic conditions. The carotid body (CB) is the ...
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Reduced expression of mitochondrial complex I subunit Ndufs2 does not impact healthspan in mice
McElroy, Gregory S.; Chakrabarty, Ram P.; D’Alessandro, Karis B.; Vasan, Karthik; Tan, Jerica; Stoolman, Joshua S.; Gao Chen, Lin; López Barneo, José; Navdeep S. (Nature Publishing Group, 2022)Aging in mammals leads to reduction in genes encoding the 45-subunit mitochondrial electron transport chain complex I. ...
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Regulation of oxygen sensing by ion channels
López Barneo, José; Toro Estévez, Raquel del; Levitski, Konstantín; Chiara, María D.; Ortega Sáenz, Patricia (2004)O2 sensing is of critical importance for cell survival and adaptation of living organisms to changing environments or ...
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Resistance of subventricular neural stem cells to chronic hypoxemia despite structural disorganization of the germinal center and impairment of neuronal and oligodendrocyte survival
D'Anglemont De Tassigny, Xavier; Sirerol-Piquer, M Salomé; Gómez-Pinedo, Ulises; Pardal Redondo, Ricardo; Bonilla, Sonia; Capilla González, Vivian; López Barneo, José (Dove Medical Press Ltd., 2015)Chronic hypoxemia, as evidenced in de-acclimatized high-altitude residents or in patients with chronic obstructive ...
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Rotenone selectively occludes sensitivity to hypoxia in rat carotid body glomus cells
Ortega Sáenz, Patricia; Pardal Redondo, Ricardo; García Fernández, María; López Barneo, José (Wiley-Blackwell Publishing Ltd., 2003)Carotid body glomus cells release transmitters in response to hypoxia due to the increase of excitability resulting from ...
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Artículo
Secretory responses of intact glomus cells in thin slices of rat carotid body to hypoxia and tetraethylammonium
Pardal Redondo, Ricardo; Ludewig, Uwe; García Hirschfeld, Julia; López Barneo, José (2000)We have developed a thin-slice preparation of whole rat carotid body that allows us to perform patch-clamp recording of ...
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Artículo
Selective accumulation of biotin in arterial chemoreceptors: requirement for carotid body exocytotic dopamine secretion
Ortega Sáenz, Patricia; Macías Gutiérrez, David; Levitsky, Konstantin L.; Rodríguez Gómez, José Antonio; González Rodríguez, Patricia; Bonilla Henao, Victoria; Arias-Mayenco, Ignacio; López Barneo, José (2016-12)Biotin is a water-soluble vitamin required for the function of carboxylases as well asfor the regulation of gene expression. ...
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Artículo
Selective Glial Cell Line-Derived Neurotrophic Factor Production in Adult Dopaminergic Carotid Body Cells In Situ and after Intrastriatal Transplantation
Villadiego Luque, Francisco Javier; Méndez Ferrer, Simón; Valdés Sánchez, Teresa; Silos Santiago, Inmaculada; Fariñas, Isabel; López Barneo, José; Toledo Aral, Juan José (2005)Glial cell line-derived neurotrophic factor (GDNF) exerts a notable protective effect on dopaminergic neurons in rodent ...
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Artículo
Single K+ channels in membrane patches of arterial chemoreceptor cells are modulated by 02 tension
Ganfornina, María Dolores; López Barneo, José (1991)Type I cells of the carotid body are known to participate in the detection of 02 tension in arterial blood but the primary ...