Listar Artículos (Fisiología Médica y Biofísica) por título
Mostrando ítems 301-320 de 332
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The HERC1 ubiquitin ligase regulates presynaptic membrane dynamics of central synapses
(Nature Research, 2020-07-21)HERC1 is a ubiquitin ligase protein, which, when mutated, induces several malformations and intellectual disability in ...
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The high mobility group protein HMG20A cooperates with the histone reader PHF14 to modulate TGF and Hippo pathways
(OXFORD UNIV PRESS, 2022)High mobility group (HMG) proteins are chromatin regulators with essential functions in development, cell differentiation ...
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The human-specific duplicated α7 gene inhibits the ancestral α7, negatively regulating nicotinic acetylcholine receptor-mediated transmitter release
(Amer Soc Biochemistry Molecular Biology Inc, 2021)Gene duplication generates new functions and traits, enabling evolution. Human-specific duplicated genes in particular are ...
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The Mitochondrial SDHD Gene Is Required for Early Embryogenesis, and Its Partial Deficiency Results in Persistent Carotid Body Glomus Cell Activation with Full Responsiveness to Hypoxia
(2004)The SDHD gene encodes one of the two membrane-anchoring proteins of the succinate dehydrogenase (complex II) of the ...
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The mouse levator auris longus muscle: an amenable model system to study the role of postsynaptic proteins to the maintenance and regeneration of the neuromuscular synapse
(Frontiers Media S.A., 2020)The neuromuscular junction (NMJ) is the peripheral synapse that controls the coordinated movement of many organisms. The ...
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The RhoB small GTPase in physiology and disease
(2016-10-23)RhoB is a Rho family GTPase that is highly similar to RhoA and RhoC, yet has distinct functions in cells. Its unique ...
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The role of non-coding RNAs in autophagy during carcinogenesis
(Frontiers Media S.A., 2022)Macroautophagy (autophagy herein) is a cellular stress response and a survival pathway involved in self-renewal and quality ...
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The spatial pattern of exocytosis and post-exocytic mobility of synaptopHluorin in mouse motor nerve terminals
(Wiley, 2009-03)We monitored the spatial distribution of exo- and endocytosis at 37◦C in mouse motor nerve terminals expressing synaptopHluorin ...
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The synaptic vesicle protein CSP alpha prevents presynaptic degeneration
(CELL PRESS, 2004-04-22)Cysteine string protein α (CSPα)—an abundant synaptic vesicle protein that contains a DNA-J domain characteristic of Hsp40 ...
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The systemic administration of oleoylethanolamide exerts neuroprotection of the nigrostriatal system in experimental Parkinsonism
(CINP, 2013)Oleoylethanolamide (OEA) is an agonist of the peroxisome proliferator-activated receptor α (PPARα) and has been described ...
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Theranostics in boron neutron capture therapy
(MDPI, 2021-04-10)Boron neutron capture therapy (BNCT) has the potential to specifically destroy tumor cells without damaging the tissues ...
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Thyrotropin-releasing-hormone (TRH) and its physiological metabolite TRH-OH inhibit Na+ channel activity in mammalian septal neurons
(1990)The interaction of thyrotropin-releasing hormone (TRH) and its physiological metabolite TRH-OH with Na+ channels was studied ...
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Toward a New Paradigm in Resistance Training by Means of Velocity Monitoring: A Critical and Challenging Narrative
(Springer, 2022-09-16)For more than a century, many concepts and several theories and principles pertaining to the goals, organization, methodology ...
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Transcriptomic analysis reveals an association of FCGBP with Parkinson’s disease
(Nature Research, 2022-11-12)Transcriptomics in Parkinson’s disease (PD) offers new insights into the molecular mechanism of PD pathogenesis. Several ...
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Transcriptomic and cellular decoding of regional brain vulnerability to neurogenetic disorders
(Nature Portfolio, 2020)Neurodevelopmental disorders have a heritable component and are associated with region specific alterations in brain ...
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Transcriptomic and connectomic correlates of differential spatial patterning among gliomas
(Oxford University Press, 2022-10-18)Unravelling the complex events driving grade-specific spatial distribution of brain tumour occurrence requires rich datasets ...
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Transgenic NADH dehydrogenase restores oxygen regulation of breathing in mitochondrial complex I-deficient mice
(NATURE PUBLISHING GROUP, 2023)The hypoxic ventilatory response (HVR) is a life-saving reflex, triggered by the activation of chemoreceptor glomus cells ...
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Trasplante de células naturales "dopaminotróficas" nuevo concepto terapeútico antiparkinsoniano
(Viguera, 2003)Aim and method. Parkinson's disease is caused by the degeneration of dopamineric neurons of substantia nigra projecting ...
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Treatment with trkC agonist antibodies delays disease progression in neuromuscular degeneration (nmd) mice
(OXFORD UNIV PRESS, 2005)Spinal muscular atrophy with respiratory distress type 1 (SMARD1) is a fatal autosomal recessive disorder seen in infants. ...
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Trophic restoration of the nigrostriatal dopaminergic pathway in long-term carotid body-grafted parkinsonian rats
(2003)We studied the mechanisms underlying long-term functional recovery of hemiparkinsonian rats grafted intrastriatally with ...