Listar Artículos (Fisiología Médica y Biofísica) por título
Mostrando ítems 205-224 de 332
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Neurotransmitter Modulation of Carotid Body Germinal Niche
(MDPI AG, 2020-11-03)The carotid body (CB), a neural-crest-derived organ and the main arterial chemoreceptor in mammals, is composed of clusters ...
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NLRP3-inflammasome inhibition prevents high fat and high sugar diets-induced heart damage through autophagy induction
(Impact Journals LLC, 2017-09-08)The NLRP3-inflammasome complex has emerged as an important component of inflammatory processes in metabolic dysfunction ...
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Novel SCAMPs Lacking NPF Repeats: Ubiquitous and Synaptic Vesicle-Specific Forms Implicate SCAMPs in Multiple Membrane- Trafficking Functions
(2000)In vertebrates, secretory carrier membrane proteins (SCAMPs) 1–3 constitute a family of putative membrane-trafficking ...
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Oncogenic Sox2 regulates and cooperates with VRK1 in cell cycle progression and differentiation.
(Nature Research, 2016-06-23)Sox2 is a pluripotency transcription factor that as an oncogene can also regulate cell proliferation. Therefore, genes ...
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Orai1 and TRPC1 Proteins Co-localize with CaV1.2 Channels to Form a Signal Complex in Vascular Smooth Muscle Cells
(American Society for Biochemistry and Molecular Biology, 2016)Voltage-dependent CaV1.2 L-type Ca2 channels (LTCC) are the main route for calcium entry in vascular smooth muscle ...
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Orai1α, but not Orai1β, co-localizes with TRPC1 and is required for its plasma membrane location and activation in HeLa cells
(Springer, 2022)The identification of two variants of the canonical pore-forming subunit of the Ca2+ release-activated Ca2+ (CRAC) channel ...
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Orai2 Modulates Store-Operated Ca2+ Entry and Cell Cycle Progression in Breast Cancer Cells
(MDPI, 2021-12-27)Breast cancer is a heterogeneous disease from the histological and molecular expression point of view, and this heterogeneity ...
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Overexpression of AQP3 Modifies the Cell Cycle and the Proliferation Rate of Mammalian Cells in Culture
(PUBLIC LIBRARY SCIENCE, 2015-09-14)Abnormal AQP3 overexpression in tumor cells of different origins has been reported and a role for this enhanced AQP3 ...
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Oxygen regulation of breathing is abolished in mitochondrial complex III-deficient arterial chemoreceptors
(National Academy of Sciences, 2022)Acute oxygen (O2) sensing is essential for adaptation of organisms to hypoxic environments or medical conditions with ...
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Oxygen sensing by ion channels and chemotransduction in single glomus cells
(1996)We have monitored cytosolic [Ca2+] and dopamine release in intact fura-2-loaded glomus cells with microfluoroimetry and a ...
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Oxygen-sensitive calcium channels in vascular smooth muscle and their possible role in hypoxic arterial relaxation
(1995)We have investigated the modifications of cytosolic [Ca2+] and the activity of Ca2+ channels in freshly dispersed arterial ...
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Parkinson’s disease patient-specific neuronal networks carrying the LRRK2 G2019S mutation unveil early functional alterations that predate neurodegeneration
(Springer Nature, 2021)A deeper understanding of early disease mechanisms occurring in Parkinson’s disease (PD) is needed to reveal restorative ...
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Peripheral Organ Equivalent Dose Estimation Procedure in Proton Therapy
(Frontiers Research Foundation, 2022)The aim of this work is to present a reproducible methodology for the evaluation of total equivalent doses in organs ...
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Physiological Plasticity of Neural-Crest-Derived Stem Cells in the Adult Mammalian Carotid Body
(Cell Press, 2017)Adult stem cell plasticity, or the ability of somatic stem cells to cross boundaries and differentiate into unrelated ...
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PKCα-Mediated Downregulation of RhoA Activity in Depolarized Vascular Smooth Muscle: Synergistic Vasorelaxant Effect of PKCα and ROCK Inhibition
(2019-02-18)Background/Aims: Protein kinase C (PKC)- and RhoA/Rho-associated kinase (ROCK) play important roles in arterial sustained ...
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La plasticidad sináptica mediada por endocannabinoides y «trastornos por consumo de drogas»
(Elsevier, 2019)Las drogas impactan en los circuitos de recompensa cerebrales y originan depen dencia y adicción, lo que se define actualmente ...
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Platelet-activating Factor Receptor Initiates Contact of Acinetobacter baumannii Expressing Phosphorylcholine with Host Cells
(2012-06)Adhesion is an initial and important step in Acinetobacter baumannii causing infections. However, the exact molecular ...
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Podoplanin Gene Disruption in Mice Promotes in vivo Neural Progenitor Cells Proliferation, Selectively Impairs Dentate Gyrus Synaptic Depression and Induces Anxiety-Like Behaviors.
(2020-01-15)Podoplanin (Pdpn), a brain-tumor-related glycoprotein identified in humans and animals, is endogenously expressed in ...