Artículos (Farmacología): Envíos recientes
Mostrando ítems 81-100 de 223
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Dual Role of Phenyl Amides from Hempseed on BACE 1, PPARγ, and PGC-1α in N2a-APP Cells
(American Chemical Society, 2021)n Alzheimer’s disease (AD) the accumulation of amyloid β (Aβ) plaques in the brain leads to neuroinflammation, neuronal ...
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Histone Extraction from Human Articular Cartilage for the Study of Epigenetic Regulation in Osteoarthritis
(MDPI, 2022)Osteoarthritis (OA) is a chronic disease that affects articular cartilage, causing its degeneration. Although OA is one ...
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Oleuropein and its peracetylated derivative negatively regulate osteoclastogenesis by controlling the expression of genes involved in osteoclast differentiation and function
(Royal Society of Chemistry, 2020)During chronic inflammation, macrophage colony-stimulating factor (M-CSF) and receptor activator of nuclear factor-κB ...
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Role of metformin and other metabolic drugs in the prevention and therapy of endocrine-related cancers
(Elsevier, 2021)Metabolic syndrome is associated with chronic diseases, including type 2 diabetes, cardiovascular diseases, and cancer. ...
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Squalene targets pro- and anti-inflammatory mediators and pathways to modulate over-activation of neutrophils, monocytes and macrophages
(Elsevier, 2015)Squalene is a natural triterpene consumed as an integral part of the human diet. Increasing evidence demonstrates that ...
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(−)-Methyl-Oleocanthal, a New Oleocanthal Metabolite Reduces LPS-Induced Inflammatory and Oxidative Response: Molecular Signaling Pathways and Histones Epigenetic Modulation
(MDPI, 2022)The antioxidant and anti-inflammatory responses of (−)-methyl-oleocanthal (met-OLE), a new metabolite of the extra virgin ...
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Pharmacological effects of mitraphylline from Uncaria tomentosa in primary human monocytes: Skew toward M2 macrophages
(Elsevier, 2015)Ethnopharmacological relevance Uncaria tomentosa (Willdenow ex Roemer & Schultes) DC. (Rubiaceae) is a Peruvian thorny ...
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Time-of-Day Circadian Modulation of Grape-Seed Procyanidin Extract (GSPE) in Hepatic Mitochondrial Dynamics in Cafeteria-Diet-Induced Obese Rats
(MDPI, 2022)Major susceptibility to alterations in liver function (e.g., hepatic steatosis) in a prone environment due to circadian ...
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Temocillin versus meropenem for the targeted treatment of bacteraemia due to third-generation cephalosporin-resistant Enterobacterales (ASTARTÉ): protocol for a randomised, pragmatic trial
(BMJ Publishing Group, 2021)Introduction: Alternatives to carbapenems are needed in the treatment of third-generation cephalosporin-resistant ...
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Evaluación de la adecuación del tratamiento farmacológico en pacientes pluripatológicos
(Elsevier, 2013)Objetivo: Analizar la adecuación del tratamiento farmacológico y realizar, si es necesario, intervenciones para su mejora ...
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Metodología de conciliación del tratamiento farmacológico en pacientes pluripatológicos
(Elsevier, 2014)Objetivo: Realizar una revisión bibliográfica para identificar las diferentes metodologías empleadas en el proceso de ...
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Intervenciones para la mejora de la adherencia al tratamiento en pacientes pluripatológicos: resumen de revisiones sistemáticas
(Elsevier, 2016)Objetivo: Evaluar la evidencia disponible respecto a la eficacia de intervenciones destinadas a mejorar la adherencia al ...
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In vitro anticancer activity and mechanism of action of an aziridinyl galactopyranoside
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)We recently screened a series of new aziridines β-D-galactopyranoside derivatives for selective anticancer activity and ...
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Phytochemical Profile and Antibacterial Activity of Retama raetam and R. sphaerocarpa cladodes from Algeria
(SAGE Publications, 2017)Retama raetam (RR) and R. sphaerocarpa (RS) are shrubs growing in Algeria desert areas, where are commonly used as healing ...
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Induction of Apoptosis and Cell Cycle Arrest in Human Colon Carcinoma Cells by Corema album Leaves
(SAGE Publications, 2014)The leaves of Corema album (Ericaceae), an endemic shrub which grows in Atlantic coastal areas of the Iberian Peninsula, ...
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Anti-inflammatory and anticancer effects of microalgal carotenoids
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)Acute inflammation is a key component of the immune system's response to pathogens, toxic agents, or tissue injury, involving ...
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Olive-Oil-Derived Polyphenols Effectively Attenuate Inflammatory Responses of Human Keratinocytes by Interfering with the NF-κB Pathway
(Wiley, 2019)Primary human keratinocytes are pretreated with HTy-Ac or HTy for 30 min and stimulated with IL-1β or Toll-like receptor ...
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Polyphenolic Extract (PE) from Olive Oil Exerts a Potent Immunomodulatory Effect and Prevents Graft-versus-Host Disease in a Mouse Model
(Elsevier, 2020)Polyphenols are a group of chemical substances found in plants, with immunomodulatory, antiproliferative, and anti-inflammatory ...
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Remdesivir and mortality reduction in COVID-19 patients: a systematized subgroup analysis of clinical trials
(Sociedad Española de Farmacia Hospitalaria, 2021)Objective: Remdesivir has not shown survival benefit for patients with severe COVID-19. However, subgroup analysis of ...
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Intermatrix synthesis of monometallic and magnetic metal/metal oxidenanoparticles with bactericidal activity on anionic exchange polymers†
(The Royal Society of Chemistry, 2012)In this communication, the synthesis of nanoparticles on anionic exchange polymers by the Intermatrix Synthesis method ...