Browsing Artículos (Farmacología) by Funding agency "Ministerio de Ciencia e Innovación (MICIN). España"
Now showing items 1-16 of 16
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Article
Abrupt Photoperiod Changes Differentially Modulate Hepatic Antioxidant Response in Healthy and Obese Rats: Effects of Grape Seed Proanthocyanidin Extract (GSPE)
(MDPI, 2023-12-02)Disruptions of the light/dark cycle and unhealthy diets can promote misalignment of biological rhythms and metabolic ...
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Age-related changes in melatonin synthesis in rat extrapineal tissues
(Elsevier, 2009-05)In the search of new therapeutic targets improving the quality of life of elderly, melatonin, “the chemical expression of ...
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Article
Amoxicillin and Clarithromycin Mucoadhesive Delivery System for Helicobacter pylori Infection in a Mouse Model: Characterization, Pharmacokinetics, and Efficacy
(MDPI, 2021-01)Helicobacter pylori is the main pathogen responsible for gastric ulcers and a predisposing factor of stomach cancer. ...
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Chemo-protective activity and characterization of phenolic extracts from Corema album
(Elsevier, 2012)There is currently substantial interest in the cyto-protective effects of natural compounds against oxidative stress and ...
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Article
Chirality influence on the cytotoxic properties of anionic chiral bis(N-heterocyclic carbene)silver complexes
(Elsevier, 2022)Complexes Na3[Ag(NHCR)2], 2a-e and 2b’-c’, where NHCR is a N-heterocyclic carbene of the 2,2′-(1H-2λ3,3λ4-imidazole-1,3-diyl)dicarboxylate ...
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Article
DDX47, MeCP2, and other functionally heterogeneous factors protect cells from harmful R loops
(Elsevier, 2023)Unscheduled R loops can be a source of genome instability, a hallmark of cancer cells. Although targeted proteomic ...
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Article
Exploring Metabolic and Gut Microbiome Responses to Paraquat Administration in Male Wistar Rats: Implications for Oxidative Stress
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)In this study, we examined the metabolic and gut microbiome responses to paraquat (PQ) in male Wistar rats, focusing on ...
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Article
Extra virgin olive oil polyphenolic extracts downregulate inflammatory responses in LPS-activated murine peritoneal macrophages suppressing NFκB and MAPK signalling pathways
(2014)Extra virgin olive oil (EVOO) is obtained from the fruit of the olive tree Olea europaea L. Phenolic compounds present in ...
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Functional Features of the Exopolysaccharide Extracts Produced by Lactiplantibacillus Strains Isolated from Table Olives
(Royal Society of Chemistry, 2024)This study evaluates the functional characteristics of the exopolysaccharide (EPS) extracts produced by various strains ...
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Article
pH-temperature dual-sensitive nucleolipid-containing stealth liposomes anchored with PEGylated AuNPs for triggering delivery of doxorubicin
(Elsevier, 2022)Liposomes (Lip) are useful nanocarriers for drug delivery and cancer nanomedicine because of their ability to efficiently ...
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Article
Photoperiod Conditions Modulate Serum Oxylipins Levels in Healthy and Obese Rats: Impact of Proanthocyanidins and Gut Microbiota
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)Seasonal rhythms are emerging as a key factor influencing gut microbiota and bioactive compounds functionality as well as ...
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Article
Preventive effect of the microalga Chlamydomonas debaryana on the acute phase of experimental colitis in rats
(Cambridge University Press, 2014)Inflammatory bowel diseases (IBD) are characterised by chronic uncontrolled inflammation of intestinal mucosa. Diet and ...
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Article
Protective effect of ellagic acid, a natural polyphenolic compound, in a murine model of Crohn’s disease
(Elsevier, 2011-10)Current epidemiological and experimental studies support a beneficial role of dietary polyphenols in several gastrointestinal ...
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Article
Repurposing Study of 4-Acyl-1-phenylaminocarbonyl-2-substituted-piperazine Derivatives as Potential Anticancer Agents-In Vitro Evaluation against Breast Cancer Cells
(MDPI, 2023)first_pagesettingsOrder Article Reprints Open AccessArticle Repurposing Study of 4-Acyl-1-phenylaminocarbonyl-2-substituted-piperazine ...
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Article
Rhythm and ROS: Hepatic Chronotherapeutic Features of Grape Seed Proanthocyanidin Extract Treatment in Cafeteria Diet-Fed Rats
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)Polyphenols play a key role in the modulation of circadian rhythms, while the cafeteria diet (CAF) is able to perturb the ...
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Article
Role of metformin and other metabolic drugs in the prevention and therapy of endocrine-related cancers
(Elsevier, 2021)Metabolic syndrome is associated with chronic diseases, including type 2 diabetes, cardiovascular diseases, and cancer. ...