Article
Multivalent glycoligands with lectin/enzyme dual specificity: self-deliverable glycosidase regulators
Author/s | González Cuesta, Manuel
Goyard, David Nanba, Eiji Higaki, Katsumi García Fernández, José Manuel Renaudet, Olivier Ortiz Mellet, Carmen ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
Department | Universidad de Sevilla. Departamento de Química orgánica |
Date | 2019 |
Published in |
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Abstract | Multivalent mannosides with inherent macrophage recognition abilities, built on β-cyclodextrin, RAFT cyclopeptide or peptide dendrimer cores, trigger selective inhibition of lysosomal β-glucocerebrosidase or α-mannosidase ... Multivalent mannosides with inherent macrophage recognition abilities, built on β-cyclodextrin, RAFT cyclopeptide or peptide dendrimer cores, trigger selective inhibition of lysosomal β-glucocerebrosidase or α-mannosidase depending on valency and topology, offering new opportunities in multitargeted drug design |
Project ID. | SAF2016-76083-R and RTI2018-097609-B-C21
![]() FQM2012- 1467 ![]() |
Citation | González Cuesta, M., Goyard, D., Nanba, E., Higaki, K., García Fernández, J.M., Renaudet, O. y Ortiz Mellet, C. (2019). Multivalent glycoligands with lectin/enzyme dual specificity: self-deliverable glycosidase regulators. Chemical Communications, 55, 12845-12848. |
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