Listar Artículos (Bioquímica y Biología Molecular) por título
Mostrando ítems 47-66 de 223
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Defective lysosomal proteolysis and axonal transport are early pathogenic events that worsen with age leading to increased APP metabolism and synaptic Abeta in transgenic APP/PS1 hippocampus
(2012)Background: Axonal pathology might constitute one of the earliest manifestations of Alzheimer disease. Axonal dystrophies ...
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Deletion of caspase-8 in mouse myeloid cells blocks microglia pro-inflammatory activation and confers protection in MPTP neurodegeneration model
(Impact Journals, LLC, 2015)Increasing evidence involves sustained pro-inflammatory microglia activation in the pathogenesis of different neurodegenerative ...
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Dendritic cells as a therapeutic strategy in acute myeloid leukemia: vaccines
(MDPI, 2024-02)Dendritic cells (DCs) serve as professional antigen-presenting cells (APC) bridging innate and adaptive immunity, playing ...
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Dendritic cells: the yin and yang in disease progression
(Frontiers Media, 2024-01-04)Dendritic cells (DCs) are antigen presenting cells that link innate and adaptive immunity. DCs have been historically ...
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Diagnostic utility of oxidative damage markers for early rheumatoid arthritis in non-smokers and negative anti-CCP patients
(Gobierno de Navarra, 2014)Fundamento. A pesar del desarrollo de nuevos marcadores y cri- terios diagnósticos para la artritis reumatoide (AR), todavía ...
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Dietary fatty acids in postprandial triglyceride-rich lipoproteins modulate human monocyte-derived dendritic cell maturation and activation
(MDPI, 2020)Dietary fatty acids have been demonstrated to modulate systemic inflammation and induce the postprandial inflammatory ...
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Diseño y escalado de un proceso biotecnológico de valorización de suero lácteo mediante la producción de ácido láctico
(Universidad Pablo de Olavide, 2014)Motivación: La industria quesera genera grandes cantidades de suero lácteo, líquido que queda tras la separación de la ...
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Diseño y perspectiva longitudinal de un proyecto de biotecnología farmacéutica basado en la economía circular
(Real e Ilustre Colegio Oficial de Farmacéuticos, 2023-07)Dentro de la asignatura de “Biotecnología Farmacéutica” del grado de Farmacia de la Universidad de Sevilla, sus competencias ...
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Disruption of Amyloid Plaques Integrity Affects the Soluble Oligomers Content from Alzheimer Disease Brains
(Public Library of Science, 2014)The implication of soluble Abeta in the Alzheimer's disease (AD) pathology is currently accepted. In fact, the content of ...
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Distinct disease-sensitive GABAergic neurons in the perirhinal cortex of Alzheimer's mice and patients
(Wiley Open Access, 2019)Neuronal loss is the best neuropathological substrate that correlates with cortical atrophy and dementia in Alzheimer’s ...
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Distinct Microglial Responses in Two Transgenic Murine Models of TAU Pathology
(Frontiers Media Research Foundation, 2018-11-14)Microglial cells are crucial players in the pathological process of neurodegenerative diseases, such as Alzheimer’s disease ...
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Divergent Effects of Metformin on an Inflammatory Model of Parkinson’s Disease
(Frontiers Media, 2018)The oral antidiabetic drug metformin is known to exhibit anti-inflammatory properties through activation of AMP kinase, ...
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Docosahexaenoic acid reduces microglia phagocytic activity via miR-124 and induces neuroprotection in rodent models of spinal cord contusion injury
(Oxford University Press, 2019-07-15)Microglia are activated after spinal cord injury (SCI), but their phagocytic mechanisms and link to neuroprotection remain ...
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Dual roles of Aβ in proliferative processes in an amyloidogenic model of Alzheimer’s disease
(Nature Research (part of Springer Nature), 2017)Alzheimer’s disease is a major neurodegenerative disorder that leads to severe cognitive deficits in the elderly population. ...
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Dysfunction of the unfolded protein response increases neurodegeneration in aged rat hippocampus following proteasome inhibition
(Wiley-Blackwell, 2009)Dysfunctions of the ubiquitin proteasome system (UPS) have been proposed to be involved in the aetiology and/or progression ...
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Dysregulation of the Hippo Pathway Signaling in Aging and Cancer
(Elsevier, 2019)Human beings are facing emerging degenerative and cancer diseases, in large part, as a consequence of increased life ...
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Early-life stress elicits peripheral and brain immune activation differently in wild type and 5xFAD mice in a sex-specific manner
(BMC, 2022)Background The risk of developing Alzheimer’s disease (AD) is modulated by genetic and environmental factors. Early-life ...
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Eco-energetic Management of Activated Sludge Derived from Slaughterhouse Wastewater Treatment: Pre-treatments for Enhancing Biogas Production Under Anaerobic Conditions
(Royal Society of Chemistry, 2020)In this paper different pre-treatments (involving temperature, pressure and enzymatic processes) were applied to activated ...
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Editorial: Factors contributing to dopaminergic cell death
(Frontiers Media S.A., 2023) -
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Editorial: Neurodegeneration: From Genetics to Molecules (Part II)
(Frontiers Media, 2021)Among non-transmissible chronic diseases, neurodegenerative complications have become a big challenge in public health. ...