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Artículo
Both p62/SQSTM1-HDAC6-dependent autophagy and the aggresome pathway mediate CDK1 degradation in human breast cancer
(Nature Publishing Group, 2017)
Cyclin-dependent kinase 1 (CDK1) is the central mammalian regulator of cell proliferation and a promising therapeutic target for breast cancer. In fact, CDK1 inhibition downregulates survival and induces apoptosis. Due to ...
Artículo
Epidemiological and Clinical Complexity of Amoxicillin-Clavulanate- Resistant Escherichia coli
(American Society for Microbiology, 2013-07)
Two hundred twelve patients with colonization/infection due to amoxicillin-clavulanate (AMC)-resistant Escherichia coli were studied. OXA-1- and inhibitor-resistant TEM (IRT)-producing strains were associated with urinary ...
Artículo
The underlying process of early ecological and genetic differentiation in a facultative mutualistic Sinorhizobium meliloti population
(Nature Publishing Group, 2017)
The question of how genotypic and ecological units arise and spread in natural microbial populations remains controversial in the field of evolutionary biology. Here, we investigated the early stages of ecological and ...
Artículo
Preparation and Characterization of New Liposomes. Bactericidal Activity of Cefepime Encapsulated into Cationic Liposomes
(MDPI, 2019)
Cefepime is an antibiotic with a broad spectrum of antimicrobial activity. However, this antibiotic has several side effects and a high degradation rate. For this reason, the preparation and characterization of new liposomes ...
Artículo
Quantitative Real-Time PCR for Detection of Acinetobacter baumannii Colonization in the Hospital Environment
(American Society of Microbiology, 2012)
A real-time PCR assay was developed for detecting the presence of Acinetobacter baumannii on hospital equipment and compared to conventional bacterial culture using 100 hospital environmental samples. The real-time PCR ...
Artículo
Sinorhizobium fredii HH103 invades lotus burttii by crack entry in a nod factor- and surface polysaccharide-dependent manner
(American Phytopathological Society, 2016)
Sinorhizobium fredii HH103-Rifr, a broad host range rhizobial strain, induces nitrogen-fixing nodules in Lotus burttii but ineffective nodules in L. japonicus. Confocal microscopy studies showed that Mesorhizobium loti ...
Artículo
Complete Assembly of the Genome of an Acidovorax citrulli Strain Reveals a Naturally Occurring Plasmid in This Species
(Frontiers Media, 2019)
Acidovorax citrulli is the causal agent of bacterial fruit blotch (BFB), a serious threat to cucurbit crop production worldwide. Based on genetic and phenotypic properties, A. citrulli strains are divided into two major ...
Artículo
Regulation of Protein Secretion Systems Mediated by Cyclic Diguanylate in Plant-Interacting Bacteria
(Frontiers Research Foundation, 2019-06-12)
The ubiquitous second messenger cyclic diguanylate (c-di-GMP) is involved in the regulation of different processes in bacteria. In phytopathogens, intracellular fluctuations in the concentration of this molecule contribute ...
Artículo
Intestinal colonization due to Escherichia coli ST131: Risk factors and prevalence
(Biomed Central, 2018-11-15)
Background Escherichia coli sequence type 131 (ST131) is a successful clonal group that has dramatically spread during the last decades and is considered an important driver for the rapid increase of quinolone resistance ...
Artículo
Emerging therapies for multidrug resistant Acinetobacter baumannii
(Cell Press, 2013-03)
The global emergence of multidrug resistant Acinetobacter baumannii has reduced the number of clinically available antibiotics that retain activity against this pathogen. For this reason, the development of novel prevention ...