• PhD Thesis
  

  Estudio de la ubicuitilación del complejo MRN mediada por SCF(bTrCP/FBXW7): implicaciones biológicas 

  Belmonte Fernández, Alejandro (2023-07-07)

  El cisplatino, como otros fármacos basados en platino, se encuentra entre los compuestos más usados en las quimioterapias ...

• Article
  

  Cisplatin-induced Cell Death Increases the degradation of the MRE11-RAD50-NBS1 Complex Through the Autophagy/lysosomal Pathway 

  Belmonte Fernández, Alejandro; Herrero Ruiz, Joaquín; Galindo Moreno, María; Limón Mortés, María Cristina; Mora Santos, María del Mar; Sáez, Carmen; Japón, Miguel A.; Tortolero García, María Dolores; Romero Portillo, Francisco (Springer Nature, 2023)

  Cisplatin and other platinum-based anticancer agents are among the most widely used chemotherapy drugs in the treatment ...

• Article
  

  Membrane vesicle engineering with “à la carte” bacterial-immunogenic molecules for organism-free plant vaccination 

  Jiménez Guerrero, Irene; López Baena, Francisco Javier; Borrero de Acuña, José Manuel; Pérez Montaño, Francisco de Asís (Wiley-Blackwell, 2023)

  The United Nations heralds a world population exponential increase exceeding 9.7 billion by 2050. This poses the challenge ...

• Article
  

  Outpatient Parenteral Antibiotic Treatment vs Hospitalization for Infective Endocarditis: Validation of the OPAT-GAMES Criteria 

  Pericas, Juan M.; Llopis, Jaume; González Ramallo, Victor; García Leoni, M. Eugenia; Arístides de Alarcón, Rafael Luque; Fariñas, M. Carmen; Araji Tiliani, Omar; Cueto López, Marina de; Gálvez Acebal, Juan; Lepe Jiménez, José Antonio (OXFORD UNIV PRESS, 2022)

  Background. Outpatient parenteral antibiotic treatment (OPAT) programs are increasingly used to manage infective endocarditis ...

• Article
  

  Killing in the name of: T6SS structure and effector diversity 

  Allsopp, Luke P.; Bernal Guzmán, Patricia (Microbiology Society, 2023)

  The life of bacteria is challenging, to endure bacteria employ a range of mechanisms to optimize their environment, ...

• PhD Thesis
  

  Optimisation of the therapeutic potential of fosfomycin against Enterobacteriaceae: characterisation of genetic and physiological factors related to resistance and antimicrobial activity 

  Ortiz Padilla, Miriam (2023-05-30)

  Since the discovery of the first antimicrobials, bacteria with resistance mechanisms against them have been detected. The ...

• Article
  

  Sinorhizobium meliloti DnaJ Is Required for Surface Motility, Stress Tolerance, and for Efficient Nodulation and Symbiotic Nitrogen Fixation 

  Brito Santana, Paula; Duque Pedraza, Julián J.; Bernabéu Roda, Lydia M.; Carvia-Hermoso, Cristina; Cuéllar, Virginia; Fuentes Romero, Francisco; Acosta Jurado, Sebastián; Vinardell González, José María; Soto, María J. (Multidisciplinary Digital Publishing Institute (MDPI), 2023)

  Bacterial surface motility is a complex microbial trait that contributes to host colonization. However, the knowledge about ...

• Article
  

  White Paper: Bridging the gap between surveillance data and antimicrobial stewardship in the animal sector-practical guidance from the JPIAMR ARCH and COMBACTE-MAGNET EPI-Net networks 

  Compri, M; Mader, R; Mazzolini, E; de Angelis, G; Mutters, NT; Rajendran, NB; López Cerero, Lorena (Oxford University Press, 2020)

  Background: The JPIAMR ARCH and COMBACTE-MAGNET EPI-Net networks have joined efforts to formulate a set of target actions ...

• Article
  

  Assessing the Impact of SARS-CoV-2 Lineages and Mutations on Patient Survival 

  Loucera, Carlos; Perez-Florido, Javier; Casimiro-Soriguer, Carlos S.; Ortuno, Francisco M.; Carmona, Rosario; Bostelmann, Gerrit; Rodríguez-Baño, Jesús; Romero Gómez, Manuel; Lepe Jiménez, José Antonio; Dopazo, Joaquin (MDPI, 2022)

  Objectives: More than two years into the COVID-19 pandemic, SARS-CoV-2 still remains a global public health problem. ...

• Article
  

  Microbial biotechnology in the effort to end hunger 

  Ramos, Juan Luis; Bernal Guzmán, Patricia; Salvachua, Davinia (Wiley-Blackwell, 2023)
• PhD Thesis
  

  Strategies to potentiate bactericidal antimicrobial activity based on the suppression of bacterial stress response systems 

  Díaz Díaz, Sara (2023-05-25)

  One of the major threats to human health is the emergence of antimicrobial resistance. Since the discovery of antimicrobials, ...

• Article
  

  Silencing of SbPPCK1-3 Negatively Affects Development, Stress Responses and Productivity in Sorghum 

  Pérez López, Jesús; Feria Bourrellier, Ana Belén; Gandullo Tovar, Jacinto Manuel; Osa Fernández, Clara de la; Jiménez Guerrero, Irene; Echevarría, Cristina; Monreal Hermoso, José Antonio; García-Mauriño Ruiz-Berdejo, Sofía (Multidisciplinary Digital Publishing Institute (MDPI), 2023)

  Phosphoenolpyruvate carboxylase (PEPC) plays central roles in photosynthesis, respiration, amino acid synthesis, and seed ...

• Article
  

  Evaluation of volatile organic compounds obtained from breath and feces to detect mycobacterium tuberculosis complex in wild boar (Sus scrofa) in Doñana National Park, Spain 

  Nol, Pauline; Ionescu, Radu; Welearegay, Tesfalem Geremariam; Barasona, José Ángel; Vicente, Joaquín; Beleño-Sáenz, Kelvin de Jesús; Torres Sánchez, María José; Rhyan, Jack (MDPI, 2020)

  The presence of Mycobacterium tuberculosis complex (MTBC) in wild swine, such as in wild boar (Sus scrofa) in Eurasia, is ...

• Article
  

  Editorial: Early Signaling in the Rhizobium-legume Symbiosis 

  Soto, María J.; Staehelin, Christian; Gourion, Benjamin; Cárdenas, Luis; Vinardell González, José María (Frontiers Media S.A., 2022)
• Article
  

  Calmodulin in Paramecium: Focus on Genomic Data 

  Villalobo Polo, Eduardo; Gutiérrez Pozo, Gabriel; Villalobo, Antonio (MDPI, 2022)

  Calcium (Ca2+) is a universal second messenger that plays a key role in cellular signaling. However, Ca2+ signals are ...

• Article
  

  Genomic analysis of 40 prophages located in the genomes of 16 carbapenemase-producing clinical strains of Klebsiella pneumoniae 

  Bleriot, Inés; Trastoy, Rocío; Blasco, Lucía; Fernández-Cuenca, Felipe; Ambroa, Antón; Fernández-García, Laura; Pascual Hernández, Álvaro; Tomás, María (2020)

  Klebsiella pneumoniae is the clinically most important species within the genus Klebsiella and, as a result of the continuous ...

• Article
  

  MDR Shigella sonnei in Spain: an ever-evolving emerging threat? 

  Ortiz de la Rosa, José Manuel; Rodríguez Villodres, Ángel; Casimiro-Soriguer, Carlos S.; Ruiz Pérez de Pipaón, Maite; Briones, Eduardo; Aznar Fernández, María; Lepe Jiménez, José Antonio (Oxford University Press, 2022-09-05)

  Background Seven CTX-M-27-producing Shigella sonnei strains were isolated at the University Hospital Virgen del Rocío ...

• Article
  

  FlowUTI An interactive web-application for optimizing the use of flow cytometry as a screening tool in urinary tract infections 

  Martín Gutiérrez, Guillermo; Martín Pérez, Carlos; Toledo, Héctor; Sánchez-Cantalejo Ramírez, Emilio; Lepe Jiménez, José Antonio (Public Library of Science, 2022-11-08)

  Due to the high prevalence of patients attending with urinary tract infection (UTI) symptoms, the use of flow-cytometry ...

• Article
  

  Molecular epidemiology of paediatric invasive pneumococcal disease in Andalusia, Spain 

  Felipe, Beatriz de; Obando Pacheco, Pablo; Carazo Gallego, Begoña; Martín López, David; Santos Pérez, José Luis; González Jiménez, Yolanda; Torres Sánchez, María José; Obando Santaella, Ignacio (Cambridge University Press, 2022-08-22)

  This study aimed to assess the impact of the introduction of pneumococcal conjugate vaccine 13 (PCV13) on the molecular ...

• PhD Thesis
  

  Factores de movilización y disminución del riesgo en la biodisponibilidad y degradación bacteriana de contaminantes orgánicos en sistemas porosos 

  Castilla Alcántara, José carlos (2023-03-30)

  En esta tesis doctoral se ha llevado a cabo una investigación básica sobre el proceso de biorremediación enfocado a ...

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