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Listar Artículos (Microbiología) por autor "Pascual Hernández, Álvaro"
Mostrando ítems 61-80 de 107
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Artículo
Interhospital Spread of blaVIM-1- and blaCTX-M-15-Producing K. pneumoniae ST15 on an IncR Plasmid in Southern Spain
Pérez Palacios, Patricia; Gual de Torrella, Ana; Portillo Calderón, Inés María; Recacha Villamor, Esther; Franco Álvarez de Luna, Francisco; López Cerero, Lorena; Pascual Hernández, Álvaro (Multidisciplinary Digital Publishing Institute (MDPI), 2023)In 2014–2015, the main CTX-M-15- and OXA-48-producing clone in our region was ST15. Recently, K. pneumoniae ST15 isolates ...
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Artículo
Interplay Among Different Fosfomycin Resistance Mechanisms in Klebsiella Pneumoniae
Ortiz Padilla, M.; Portillo Calderón, I.; De Gregorio Iaria, Belén; Blázquez, J.; Rodríguez-Baño, Jesús; Pascual Hernández, Álvaro; Rodríguez Martínez, José Manuel; Docobo Pérez, Fernando (American Society for Microbiology, 2021)The objectives of this study were to characterize the role of the uhpT, glpT, and fosA genes in fosfomycin resistance in ...
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Interplay between IncF plasmids and topoisomerase mutations conferring quinolone resistance in the Escherichia coli ST131 clone: stability and resistance evolution
Rodríguez Martínez, José Manuel; López Cerero, Lorena; García-Duque, Ana; Rodríguez-Baño, Jesús; Pascual Hernández, Álvaro (Springer, 2021-11-17)The Escherichia coli ST131 H30-Rx subclone vehicles CTX-M-15 plasmids and mutations in gyrA and parC conferring multidrug ...
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Intestinal colonization due to Escherichia coli ST131: Risk factors and prevalence
Morales Barroso, Isabel; López Cerero, Lorena; Navarro, María Dolores; Gutiérrez Gutiérrez, Belén; Pascual Hernández, Álvaro; Rodríguez-Baño, Jesús (Biomed Central, 2018-11-15)Background Escherichia coli sequence type 131 (ST131) is a successful clonal group that has dramatically spread during the ...
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Intracellular penetration and activity of BAY Y 3118 in human polymorphonuclear leukocytes
García Luque, Isabel; Pascual Hernández, Álvaro; Perea Pérez, Evelio José (American Society for Microbiology, 1994-01-01)The penetration of a new quinolone (BAY Y 3118) into human polymorphonuclear leukocytes (PMNs) was evaluated by a fluorometric ...
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Intracellular penetration and activity of DX-619 in human polymorphonuclear leukocytes
García Luque, Isabel; Ballesta, Sofía; Murillo del Castillo, Concepción; Perea Pérez, Evelio José; Pascual Hernández, Álvaro (American Society for Microbiology, 2006-09-01)The intracellular penetration and activity of DX-619 in human polymorphonuclear leukocytes have been evaluated. DX-619 ...
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Intracellular penetration and activity of gemifloxacin in human polymorphonuclear leukocytes
García Luque, Isabel; Pascual Hernández, Álvaro; Joyanes, Providencia; Perea Pérez, Evelio José (American Society for Microbiology, 2000-11-09)The intracellular penetration and activity of gemifloxacin in human polymorphonuclear leukocytes (PMN) were evaluated. ...
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Is reduced vancomycin susceptibility a factor associated with poor prognosis in MSSA bacteraemia?
López-Cortes, Luis Eduardo; Velasco Ramírez, María del Carmen; Retamar Gentil, Pilar; Toro López, María Dolores del; Gálvez Acebal, Juan; Cueto López, Marina de; García Luque, Isabel; Pascual Hernández, Álvaro; Rodríguez-Baño, Jesús (Oxford University Press, 2015)Objectives: The known data about the influence of vancomycin MIC on Staphylococcus aureus bacteraemia are contradictory. ...
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Klebsiella pneumoniae Strains Producing Extended-Spectrum B-Lactamases in Spain: Microbiological and Clinical Features
Ruiz de Alegría, C.; Rodríguez-Baño, Jesús; Cano, M. E.; Hernández-Bello, José R.; Calvo, J.; Román, E.; Díaz, Miguel A.; Pascual Hernández, Álvaro; Martínez-Martínez, Luis (American Society for Microbiology, 2011-03)Extended-spectrum B-lactamases (ESBL) of the CTX-M, SHV, and TEM families were recognized in 76 (67%), 31 (27%), and 6 ...
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Long-Term Control of Endemic Hospital-Wide Methicillin-Resistant Staphylococcus aureus (MRSA): The Impact of Targeted Active Surveillance for MRSA in Patients and Healthcare Workers
Rodríguez-Baño, Jesús; García, Lola; Ramírez, Encarnación; Lupión Mendoza, Carmen; Muniain Ezcurra, Miguel Angel; Velasco Ramírez, María del Carmen; Gálvez-Acebal, Juan; Toro López, María Dolores del; Millán, Antonio B.; López Cerero, Lorena; Pascual Hernández, Álvaro (Cambridge University Press, 2010-08)To evaluate the long-term impact of successive interventions on rates of methicillin-resistant Staphylococcus aureus (MRSA) ...
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Mechanisms of Tolerance and Resistance to Chlorhexidine in Clinical Strains of Klebsiella pneumoniae Producers of Carbapenemase: Role of New Type II Toxin-Antitoxin System, PemIK
Bleriot, Inés; Blasco, L.; Delgado Valverde, María Mercedes; Gual-de-Torrella, Ana; Ambroa, A.; Fernandez-Garcia, Laura; Pascual Hernández, Álvaro; Tomas, Maria (MDPI, 2020-09-02)Although the failure of antibiotic treatment is normally attributed to resistance, tolerance and persistence display a ...
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Artículo
Modelling the epidemiology of Escherichia coli ST131 and the impact of interventions on the community and healthcare centres
Talaminos Barroso, Alejandro; López Cerero, Lorena; Calvillo Arbizu, Jorge; Pascual Hernández, Álvaro; Roa Romero, Laura María; Rodríguez-Baño, Jesús (Cambridge University Press, 2016)ST131 Escherichia coli is an emergent clonal group that has achieved successful worldwide spread through a combination ...
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Artículo
Multicenter Performance Evaluation of MALDI-TOF MS for Rapid Detection of Carbapenemase Activity in Enterobacterales: The Future of Networking Data Analysis With Online Software
Gato, Eva; Anantharajah, Ahalieyah; Arroyo, Manuel J.; Artacho, María José; Caballero, Juan de Dios; Candela, Ana; Pascual Hernández, Álvaro; Oviaño, María (Frontiers Media S.A., 2022)In this study, we evaluate the performance of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry ...
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Mutant prevention concentrations of fluoroquinolones for Enterobacteriaceae expressing the plasmid-carried quinolone resistance determinant qnrA1
Pascual Hernández, Álvaro; Rodríguez Martínez, José Manuel; González Velasco, Carmen; García Luque, Isabel; Cano, María Elicier; Martínez Martínez, Luis (American Society for Microbiology, 2007-06-01)The influence of qnrA1 on the development of quinolone resistance in Enterobacteriaceae was evaluated by using the mutant ...
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Nationwide study of Escherichia coli and Klebsiella pneumoniae producing extended-spectrum β-lactamases in Spain
Hernández, J. R.; Martínez Martínez, Luis; Cantón, Rafael; Coque, T. M.; Pascual Hernández, Álvaro (American Society for Microbiology, 2005-05-01)Clonal dissemination of extended-spectrum -lactamases (ESBL) in 170 Escherichia coli isolates and 70 Klebsiella pneumoniae ...
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Off-target effects of bacillus Calmette–Guerin vaccination on immune responses to SARS-CoV-2: implications for protection against severe COVID-19
Messina, Nicole L.; Germano, Susie; McElroy, Rebecca; Rudraraju, Rajeev; Bonnici, Rhian; Pittet, Laure F.; Toro López, María Dolores del; Pascual Hernández, Álvaro; Rodríguez-Baño, Jesús (WILEY, 2022)Background and objectives. Because of its beneficial off-target effects against non-mycobacterial infectious diseases, ...
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OXA-48-Like-Producing Klebsiella pneumoniae in Southern Spain in 2014-2015
Machuca, Jesús; López Cerero, Lorena; Fernández-Cuenca, Felipe; Mora-Navas, Laura; Mediavilla-Gradolph, Concepción; López-Rodríguez, Inmaculada; Pascual Hernández, Álvaro (Oxford University Press, 2019)The aim of this study was to characterize the population structure of 56 OXA-48-like-producing Klebsiella pneumoniae ...
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Pharmacodynamics of fosfomycin: Insights into clinical use for antimicrobial resistance
Rodríguez Martínez, José Manuel; Conejo Gonzalo, Mª Carmen; Rodríguez-Baño, Jesús; Pascual Hernández, Álvaro; Docobo Pérez, Fernando (American Society for Microbiology, 2015-09-01)The aim of this study was to improve the understanding of the pharmacokinetic-pharmacodynamic relationships of fosfomycin ...
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Phenotypic and Genomic Comparison of Klebsiella pneumoniae Lytic Phages: vB_KpnM-VAC66 and vB_KpnM-VAC13
Pacios, Olga; Fernández García, Laura; Bleriot, Inés; Blasco, Lucía; Pascual Hernández, Álvaro; Tomás, María (MDPI, 2021-12-31)Klebsiella pneumoniae is a human pathogen that worsens the prognosis of many immuno compromised patients. Here, we annotated ...
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Population pharmacokinetics and pharmacodynamics of fosfomycin in non-critically ill patients with bacteremic urinary infection caused by multidrug-resistant Escherichia coli
Merino Bohórquez, Vicente; Docobo Pérez, Fernando; Sojo Dorado, Jesús; Morales, Isabel; Lupión Mendoza, Carmen; Martín, D.; Pascual Hernández, Álvaro; Rodríguez-Baño, Jesús (Elsevier, 2018)Objectives: To describe the population pharmacokinetics of fosfomycin for patients with bacteraemic urinary tract infection ...