Browsing Artículos (Genética) by Title
Now showing items 374-393 of 455
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The COP9 signalosome is vital for timely repair of DNA double-strand breaks
(Oxford University Press, 2015)The DNA damage response is vigorously activated by DNA double-strand breaks (DSBs). The chief mobilizer of the DSB response ...
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The dedicated chaperone acl4 escorts ribosomal protein rpl4 to its nuclear pre-60s assembly site
(Public Library of Science, 2015)Ribosomes are the highly complex macromolecular assemblies dedicated to the synthesis of all cellular proteins from mRNA ...
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The DNA damage response acts as a safeguardagainst harmful DNA–RNA hybrids ofdifferent origins
(EMBO Press, 2019-07-24)Despite playing physiological roles in specific situations, DNA–RNA hybrids threat genome integrity. To investigate how ...
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The effect of atypical nucleic acids structures in DNA double strand break repair: a tale of R-loops and G-quadruplexes
(Frontiers Media S.A., 2021)The fine tuning of the DNA double strand break repair pathway choice relies on different regulatory layers that respond ...
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The Emerging Role of RNA Modifications in DNA Double-Strand Break Repair
(Frontiers Media S.A., 2021)The correct repair of DNA double-strand breaks is essential for maintaining the stability of the genome, thus ensuring the ...
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The essential WD-repeat protein Rsa4p is required for rRNA processing and intra-nuclear transport of 60S ribosomal subunits
(Oxford University Press, 2005)We report the characterization of a novel factor, Rsa4p (Ycr072cp), which is essential for the synthesis of 60S ribosomal ...
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The eukaryote-specific N-terminal extension of ribosomal protein S31 contributes to the assembly and function of 40S ribosomal subunits
(Oxford University Press, 2016)The archaea-/eukaryote-specific 40S-ribosomal-subunit protein S31 is expressed as an ubiquitin fusion protein in eukaryotes ...
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The Fanconi Anemia Pathway Protects Genome Integrity from R-loops
(Public Library of Science, 2015)Co-transcriptional RNA-DNA hybrids (R loops) cause genome instability. To prevent harmful R loop accumulation, cells have ...
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The flavoproteins CryD and VvdA cooperate with the white collar protein WcoA in the Control of photocarotenogenesis in Fusarium fujikuroi
(Public Library of Science, 2015)Light stimulates carotenoid biosynthesis in the ascomycete fungus Fusarium fujikuroi through transcriptional activation ...
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The Fungal Protein Mes1 Is Required for Morphogenesis and Virulence in the Dimorphic Phytopathogen Ustilago maydis
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)Polarized growth is a defining property of filamentous fungi, which plays an important role in different aspects of their ...
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The fungal type II myosin in Penicillium marneffei, MyoB, is essential for chitin deposition at nascent septation sites but not actin localization
(American Society for Microbiology, 2011-03)Cytokinesis is essential for proliferative growth but also plays equally important roles during morphogenesis and development. ...
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The GATC-binding protein SeqA is required for bile resistance and virulence in Salmonella enterica serovar Typhimurium
(American Society for Microbiology, 2007)Disruption of the seqA gene of Salmonella enterica serovar Typhimurium causes defects similar to those described in E. ...
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The Helicase PIF1 Facilitates Resection over Sequences Prone to Forming G4 Structures
(Elsevier, 2018)DNA breaks are complex lesions that can be repaired either by non-homologous end joining (NHEJ) or by homologous recombination ...
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The human nucleoporin Tpr protects cells from RNA-mediated replication stress
(Springer Nature, 2021)Although human nucleoporin Tpr is frequently deregulated in cancer, its roles are poorly understood. Here we show that Tpr ...
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The NEL Family of Bacterial E3 Ubiquitin Ligases
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)Some pathogenic or symbiotic Gram-negative bacteria can manipulate the ubiquitination system of the eukaryotic host cell ...
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The Npl3 hnRNP prevents R-loop-mediated transcription–replication conflicts and genome instability
(Cold Spring Harbor Laboratory Press, 2013)Transcription is a major obstacle for replication fork (RF) progression and a cause of genome instability. Part of this ...
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The oxygenase CAO-1 of Neurospora crassa is a resveratrol cleavage enzyme.
(American Society for Microbiology, 2013)The genome of the ascomycete Neurospora crassa encodes CAO-1 and CAO-2, two members of the carotenoid cleavage oxygenase ...
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The Phycomyces madA gene encodes a blue-light photoreceptor for phototropism and other light responses
(National Academy of Sciences, 2006)Phycomyces blakesleeanus is a filamentous zygomycete fungus that produces striking elongated single cells that extend up ...