Listar Artículos (Genética) por título
Mostrando ítems 440-459 de 461
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UAP56/DDX39B is a major cotranscriptional RNA–DNA helicase that unwinds harmful R loops genome-wide
(Cold Spring Harbor Laboratory Press, 2020)Nonscheduled R loops represent a major source of DNA damage and replication stress. Cells have different ways to prevent ...
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Ubiquitin and Ubiquitin-Like Proteins and Domains in Ribosome Production and Function: Chance or Necessity?
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)Ubiquitin is a small protein that is highly conserved throughout eukaryotes. It operates as a reversible post-translational ...
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UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors
(Elsevier, 2020)Genomic instability can be a hallmark of both human genetic disease and cancer. We identify a deleterious UBQLN4 mutation ...
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Unexpected homology between inducible cell wall protein QID74 of filamentous fungi and BR3 salivary protein of the insect Chironomus
(National Academy of Sciences, 1998)A gene, qid74, of mycoparasitic filamentous fungus Trichoderma harzianum and its allies encodes a cell wall protein that ...
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Unravelling the genetic basis of simplex Retinitis Pigmentosa cases
(Nature Publishing Group, 2017)Retinitis Pigmentosa (RP) is the most common form of inherited retinal dystrophy (IRD) characterized ultimately by ...
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Use of chitin and chitosan to produce new chitooligosaccharides by chitinase Chit42: enzymatic activity and structural basis of protein specificity
(BioMed Central, 2018)Background Chitinases are ubiquitous enzymes that have gained a recent biotechnological attention due to their ability ...
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Variation in G+C-content and codon choice: Differences among synonymous codon groups in vertebrate genes
(Oxford University Press, 1989)The relationship between G+C-content and codon usage in genes of human, mus, rat, bovine and chicken nuclear genomes was ...
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Waddington's Landscapes in the Bacterial World
(Frontiers Media, 2021)Conrad Waddington's epigenetic landscape, a visual metaphor for the development of multicellular organisms, is appropriate ...
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WASp modulates RPA function on single-stranded DNA in response to replication stress and DNA damage.
(Nature Research, 2022)Perturbation in the replication-stress response (RSR) and DNA-damage response (DDR) causes genomic instability. Genomic ...
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What causes an RNA-DNA hybrid to compromise genome integrity?
(Elsevier, 2019)Transcription is a source of genome instability that stimulates mutation and recombination. Part of the damage produced ...
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WHI-2 Regulates Intercellular Communication via a MAP Kinase Signaling Complex
(Frontiers Media, 2020)he formation of the fungal mycelial network is facilitated by somatic cell fusion of germinating asexual spores (or ...
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Xpf suppresses the mutagenic consequences of phagocytosis in Dictyostelium
(The Company of Biologists, 2016)As time passes, mutations accumulate in the genomes of all living organisms. These changes promote genetic diversity, but ...
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XRCC1 Prevents Replication Fork Instability during Misincorporation of the DNA Demethylation Bases 5-Hydroxymethyl-2′-Deoxycytidine and 5-Hydroxymethyl-2′-Deoxyuridine
(MDPI, 2022)Whilst avoidance of chemical modifications of DNA bases is essential to maintain genome stability, during evolution ...
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Xrn1 influence on gene transcription results from the combination of general effects on elongating RNA pol II and gene-specific chromatin configuration
(Taylor & Francis, 2021)mRNA homoeostasis is favoured by crosstalk between transcription and degradation machineries. Both the Ccr4-Not and the ...
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Yeast as a model system to study metabolic impact of selenium compounds
(Shared Science Publishers, 2015)Inorganic Se forms such as selenate or selenite (the two more abundant forms in nature) can be toxic in Saccharomyces ...
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Yeast Genetic Analysis Reveals the Involvement of Chromatin Reassembly Factors in Repressing HIV-1 Basal Transcription
(Public Library of Science, 2009)Rebound of HIV viremia after interruption of anti-retroviral therapy is due to the small population of CD4+ T cells that ...
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Yeast ribosomal protein L40 assembles late into precursor 60 S ribosomes and is required for their cytoplasmic maturation
(Elsevier, 2012)Background: The contribution of ribosomal proteins to ribosome assembly and function is often not well understood. Results: ...
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