Author profile: Montserrat de la Paz, Sergio
Institutional data
Name | Montserrat de la Paz, Sergio |
Department | Bioquímica Médica y Biología Molecular e Inmunología |
Knowledge area | Bioquímica y Biología Molecular |
Professional category | Profesor Titular de Universidad |
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No. publications
65
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No. visits
7869
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7429
Publications |
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Article
Effects of Malnutrition on the Immune System and Infection and the Role of Nutritional Strategies Regarding Improvements in Children’s Health Status: A Literature Review
(MDPI, 2024)
Malnutrition refers to a person’s status as under- or overnourished, and it is usually associated with an inflammation ... |
Article
Identification of the Bioavailable Peptidome of Chia Protein Hydrolysate and the In Silico Evaluation of Its Antioxidant and ACE Inhibitory Potential
(American Chemical Society, 2024)
The incorporation of novel, functional, and sustainable foods in human diets is increasing because of their beneficial effects ... |
Master's Final Project
Efecto de las lipoproteínas de alta densidad sobre la microvasculatura cerebral en la enfermedad del alzhéimer
(2023)
Las lipoproteínas de alta densidad (HDL) juegan un papel importante en la patología de la enfermedad de Alzheimer (EA) y ... |
Article
Current research on antioxidant, anti-inflammatory and anti-obesity potential of food extracts
(MDPI, 2023)
The immune-inflammatory, glucose homeostasis, and antioxidant response have a crucial role in the prevention of non-communicable ... |
Article
Lipoprotein metabolism, protein aggregation, and Alzheimer's disease: a literature review
(MDPI, 2023)
Alzheimer’s disease (AD) is the most common form of dementia. The physiopathology of AD is well described by the presence ... |
Article
Mediterranean Diet and Melatonin: A Systematic Review
(MDPI, 2023)
The Mediterranean diet (MD) has beneficial effects on human health, which is evidenced by the observation of lower incidence ... |
Article
Nutraceuticals as potential therapeutic modulators in immunometabolism
(MDPI, 2023)
Nutraceuticals act as cellular and functional modulators, contributing to the homeostasis of physiological processes. In ... |
Article
Nutritional composition, ultrastructural characterization, and peptidome profile of antioxidant hemp protein hydrolysates
(Elsevier, 2023)
Hemp is the term commonly used to refer to the variety of Cannabis sativa L. cultivated for industrial purposes. The seeds ... |
Article
Immediate-release Niacin and a Monounsaturated Fatty Acid-rich Meal on Postprandial Inflammation and Monocyte Characteristics in Men with Metabolic Syndrome
(Elsevier, 2023)
Background & aim: When considered separately, long-term immediate-release niacin and fatty meals enriched in monounsaturated ... |
Article
Modulation of Beta-Amyloid-Activated Primary Human Neutrophils by Dietary Phenols from Virgin Olive Oil
(MDPI, 2023)
The defense mechanism against harmful stimuli is inflammation. Indeed, neurodegenerative disorders can arise as a result ... |
Article
Update on Anti-Inflammatory Molecular Mechanisms Induced by Oleic Acid
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)
In 2010, the Mediterranean diet was recognized by UNESCO as an Intangible Cultural Heritage of Humanity. Olive oil is the ... |
Article
Evidence of Immunomodulatory Food-Protein Derived Peptides in Human Nutritional Interventions: Review on the Outcomes and Potential Limitations
(Mdpi, 2023)
The immune system is somehow related to all the metabolic pathways, in a bidirectional way, and the nutritional interventions ... |
Article
Sulforaphane reduces the chronic inflammatory immune response of human dendritic cells
(MDPI, 2023)
Background: Sulforaphane (SFN) is an isothiocyanate of vegetable origin with potent antioxidant and immunomodulatory ... |
Article
Antimicrobial plant-derived peptides obtained by enzymatic hydrolysis and fermentation as components to improve current food systems
(Elsevier, 2023)
Background: New challenges in our society are appearing following the emergence of antibiotic-resistant mi- croorganisms ... |
Article
Hemp protein hydrolysates modulate inflammasome-related genes in microglial cells
(MDPI, 2022)
A prolonged inflammatory response can lead to the development of neurodegenerative diseases such as Alzheimer’s disease. ... |
PhD Thesis |
Article
Antioxidant and Immunomodulatory Properties of Chia Protein Hydrolysates in Primary Human Monocyte–Macrophage Plasticity
(MDPI, 2022)
Chia (Salvia hispanica L.) seed has high potential in the development of functional food due to its protein content with ... |
Article
High-density lipoproteins and immune response: A review
(Elsevier, 2022)
High-density lipoproteins (HDLs) are heterogeneous lipoproteins that modify their composition and functionality depending ... |
Article
Moderate beer consumption and metabolic health: A comprehensive review from the lipoprotein perspective
(Elsevier Science BV, 2022)
effects on our health. Regarding cardiovascular disease, research needs to consider the amount consumed but also drinking ... |
Article
Acyclic Diterpene Phytol from Hemp Seed Oil (Cannabis sativa L.) Exerts Anti-Inflammatory Activity on Primary Human Monocytes-Macrophages
(MDPI, 2022)
Seeds from non-drug varieties of hemp (Cannabis sativa L.) have been used for traditional medicine, food, and fiber ... |
Article
Antihypertensive and Antioxidant Activity of Chia Protein Techno-Functional Extensive Hydrolysates
(MDPI, 2021)
Twelve high-quality chia protein hydrolysates (CPHs) were produced from chia protein isolate (CPI) in a pilot plant of ... |
Article |
Article
Identification and characterization of novel antioxidant protein hydrolysates from kiwicha (amaranthus caudatus l.)
(MDPI, 2021)
: Kiwicha (Amaranthus caudatus) is considered one of the few multipurpose pseudocereals for its potential use not only as ... |
Chapter of Book
Grape Seed Oil
(MDPI, 2021)
Grape seed extract has demonstrated many activities in disease prevention, such as antioxidant effects, which make it a ... |
Article
High-Density Lipoproteins and Mediterranean Diet: A Systematic Review
(MDPI, 2021)
Cardiovascular disease (CVD) is the leading cause of global mortality and the study of high-density lipoproteins (HDL) ... |
Chapter of Book
Grape (Vitis vinifera L.) Seed Oil: A Functional Food from the Winemaking Industry
(Vide Leaf, 2021)
Wine production is an ancient human activity that generates several by-products, which include some constituents known for ... |
Article
Pectins and Olive Pectins: From Biotechnology to Human Health
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
Pectins comprise complex polysaccharides rich in galacturonic acid, that exert many functions in higher plants as components ... |
Article
Bacteroides uniformis CECT 7771 alleviates inflammation within the gut-adipose tissue axis involving TLR5 signaling in obese mice
(Springer Nature, 2021)
This study investigated the immune mechanisms whereby administration of Bacteroides uniformis CECT 7771 reduces metabolic ... |
PhD Thesis
Preclinical evaluation of the immunometabolic effects of octapeptide Gpetaflr
(2021)
Existe un fuerte y creciente interés por las leguminosas como fuente de proteína que puede sustituir a la proteína animal, ... |
Article
Antioxidant and anti-inflammatory properties of bioavailable protein hydrolysates from lupin-derived agri-waste
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
Agri-food industries generate several by-products, including protein-rich materials cur-rently treated as waste. Lupine ... |
Chapter of Book
Pectins and Olive Pectins
(MDPI, 2021)
Pectins are a component of the complex heteropolysaccharide mixture present in the cell wall of higher plants. Structurally, ... |
Article
Obesity-associated metabolic disturbances reverse the antioxidant and anti-inflammatory properties of high-density lipoproteins in microglial cells
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
High-density lipoproteins (HDLs) play an important role in reverse cholesterol transport and present antioxidant properties, ... |
PhD Thesis
Efecto protector del aceite de oliva sobre la activación de la Microglía
(2020)
Un posible enfoque terapéutico para el tratamiento de enfermedades neuroinflamatorias se podría basar en la inhibición del ... |
Article
Characterization of bioactive compounds in defatted hempseed (Cannabis sativa L.) by UHPLC-HRMS/MS and anti-inflammatory activity in primary human monocytes
(Royal Society of Chemistry, 2020)
Hempseed (Cannabis sativa L.) has beneficial impact on human health mainly because of its wide variability of bioactive ... |
Article
Nutraceutical value of kiwicha (Amaranthus caudatus L.)
(Elsevier, 2020)
Amaranthus caudatus L. (Amaranthaceae), commonly known as kiwicha, is considered as one of the few multipurpose pseudocereal ... |
Article
Hemp (Cannabis sativa L.) Protein Hydrolysates Promote Anti-Inflammatory Response in Primary Human Monocytes
(MDPI, 2020)
Hemp seeds have a wide variety of chemical compounds which present biological activity. Specifically, the focus on proteins ... |
Article
Grape (Vitis vinifera L.) Seed Oil: A Functional Food from the Winemaking Industry
(MDPI, 2020)
Wine production is an ancient human activity that generates several by-products, which include some constituents known for ... |
Article
Dietary fatty acids in postprandial triglyceride-rich lipoproteins modulate human monocyte-derived dendritic cell maturation and activation
(MDPI, 2020)
Dietary fatty acids have been demonstrated to modulate systemic inflammation and induce the postprandial inflammatory ... |
Article
A lupine (Lupinus angustifolious L.) peptide prevents non-alcoholic fatty liver disease in high-fat-diet-induced obese mice
(Royal Society of Chemistry, 2020)
Bioactive peptides are related to the prevention and treatment of many diseases. GPETAFLR is an octapeptide that has been ... |
Article
Evaluation of anti-inflammatory and atheroprotective properties of wheat gluten protein hydrolysates in primary human monocytes
(MDPI, 2020)
Bioactive protein hydrolysates have been identified in several sources as possible agents in the prevention and treatment ... |
Article
Oleuropein and its peracetylated derivative negatively regulate osteoclastogenesis by controlling the expression of genes involved in osteoclast differentiation and function
(Royal Society of Chemistry, 2020)
During chronic inflammation, macrophage colony-stimulating factor (M-CSF) and receptor activator of nuclear factor-κB ... |
Article
Nutraceutical Extract from Dulse (Palmaria palmata L.) Inhibits Primary Human Neutrophil Activation
(MDPI, 2019)
Palmaria palmata L. (Palmariaceae), commonly known as "dulse", is a red alga that grows on the northern coasts of the ... |
Article
Minor compounds from virgin olive oil attenuate LPS-induced inflammation via visfatin-related gene modulation on primary human monocytes
(Wiley-Blackwell, 2019)
We have analyzed the effects of minor compounds found in the unsaponifiable fraction (UF) and in the phenolic fraction ... |
Article
GPETAFLR, a biopeptide from Lupinus angustifolius L., protects against oxidative and inflammatory damage in retinal pigment epithelium cells
(Wiley-Blackwell, 2019)
GPETAFLR, an octapeptide released from the enzymatic hydrolysis of lupine (Lupinus angustifolius L.) protein, has demonstrated ... |
Article
A microRNA expression signature of the postprandial state in response to a high-saturated-fat challenge
(Elsevier, 2018)
The postprandial hypertriglyceridemia is an important and largely silent disturbance involved in the genesis of numerous ... |
Article
Unsaponifiable fraction isolated from grape (vitis vinifera l.) seed oil attenuates oxidative and inflammatory responses in human primary monocytes
(Royal Society of Chemistry, 2018)
Grape (Vitis vinifera L.) seed has well-known potential for production of oil as a byproduct of winemaking and is a rich ... |
Article
Effects of immediate‐release niacin and dietary fatty acids on acute insulin and lipid status in individuals with metabolic syndrome
(John Wiley & Sons, 2018)
BACKGROUND The nature of dietary fats profoundly affects postprandial hypertriglyceridemia and glucose homeostasis. Niacin ... |
Patent. Invention
Uso del aceite del cáñamo para la prevención y/o el tratamiento de la fibromialgia
(Oficina Española de Patentes y Marcas (OEPM), 2017)
Uso del aceite de cáñamo para la prevención y/o el tratamiento de la fibromialgia. La presente invención se relaciona con ... |
Article
Dietary fatty acids and lipoproteins on progression of age-related macular degeneration
(CSIC, 2017)
Age-related macular degeneration (AMD) is a medical condition of central loss vision and blindness. Numerous studies have ... |
Article
Effect of metabolites of hydroxytyrosol on protection against oxidative stress and inflammation in human endothelial cells
(Elsevier, 2017)
The effects of chemically synthesized metabolites (sulfate and glucuronate forms) from hydroxytyrosol (HTyr) on oxidative ... |
Article
Tyrosol and its metabolites as antioxidative and anti-inflammatory molecules in human endothelial cells
(Royal Society of Chemistry, 2017)
Tyrosol (Tyr) is a phenolic compound found in virgin olive oil. After ingestion, Tyr undergoes extensive first pass ... |
Presentation |
Article
Dietary fatty acids on aortic root calcification in mice with metabolic syndrome
(Royal Society of Chemistry, 2017)
Metabolic syndrome (MetS) is associated with obesity, dyslipidemia, type 2 diabetes, and chronic low-grade inflammation. ... |
Article
Exogenous fatty acids and niacin on acute prostaglandin D-2 production in human myeloid cells
(Elsevier, 2017)
Niacin activates HCA2 receptor that results in the release of PGD2. However, little is known on PGD2-producing cells and ... |
Article
Leukocyte Overexpression of Intracellular NAMPT Attenuates Atherosclerosis by Regulating PPARγ-Dependent Monocyte Differentiation and Function
(Wolters Kluwer Health, 2017)
Objective-Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) mediates inflammatory and potentially proatherogenic ... |
Presentation |
Article
The effects of exogenous fatty acids and niacin on human monocyte-macrophage plasticity
(Wiley-Blackwell, 2017)
Scope: Macrophage plasticity allows adapting to different environments, having a dual activity in inflammatory-related ... |
PhD Thesis |
Article
Niacin and olive oil promote skewing to the M2 phenotype in bone marrow-derived macrophages of mice with metabolic syndrome
(Royal Society of Chemistry, 2016)
Metabolic syndrome (MetS) is associated with obesity, dyslipemia, type 2 diabetes and chronic low-grade inflammation. The ... |
Article
Olive oil and postprandial hyperlipidemia: Implications for atherosclerosis and metabolic syndrome
(Royal Society of Chemistry, 2016)
Olive oil is the primary source of fat in the Mediterranean diet, which is associated with a significant improvement in ... |
Article
Olive oil, compared to a saturated dietary fat, has a protective role on atherosclerosis in niacin-treated mice with metabolic syndrome
(Elsevier, 2016)
We aimed to investigate the impact of high-fat low-cholesterol diets rich in saturated fatty acids (HFLCD-SFAs), monounsaturated ... |
Article
The sterols isolated from evening primrose oil inhibit human colon adenocarcinoma cell proliferation and induce cell cycle arrest through upregulation of LXR
(Elsevier, 2015)
Evening primrose oil (EPO) is widely used as a dietary supplement from which beneficial effects have been reported in ... |
Article
Validation of ethnopharmacological use as anti-inflammatory of a decoction from Annona muricata leaves
(African Networks on Ethnomedicines, 2015)
Background: Through this work we evaluated the potential of the aqueous extract of Annona muricata L. leaves (AMAEL) to ... |
Article
Squalene targets pro- and anti-inflammatory mediators and pathways to modulate over-activation of neutrophils, monocytes and macrophages
(Elsevier, 2015)
Squalene is a natural triterpene consumed as an integral part of the human diet. Increasing evidence demonstrates that ... |
Article
Pharmacological effects of mitraphylline from Uncaria tomentosa in primary human monocytes: Skew toward M2 macrophages
(Elsevier, 2015)
Ethnopharmacological relevance Uncaria tomentosa (Willdenow ex Roemer & Schultes) DC. (Rubiaceae) is a Peruvian thorny ... |