Author profile: Pérez Simón, José Antonio
Institutional data
| Name | Pérez Simón, José Antonio |
| Department | Medicina |
| Knowledge area | Medicina |
| Professional category | Profesor Titular de Universidad (Pza. V) |
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Statistics
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No. publications
37
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No. visits
2630
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No. downloads
4993
| Publications |
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| PhD Thesis |
Article
 Spanish Society of Hematology and Hemotherapy expert consensus opinion for SARS-CoV-2 vaccination in onco-hematological patients
(Taylor & Francis LTD, 2022-01-01)
In the midst of the COVID-19 pandemic, different vaccines in front of SARS-CoV-2 have been approved and administered in ... |
Article
The impact of CD160 deficiency on alloreactive CD8 T cell responses and allograft rejection
(Elsevier, 2022-01-01)
CD160 is a member of the immunoglobulin superfamily with a pattern of expression mainly restricted to cytotoxic cells. To ... |
Article
Effect of Vitamin D on Graft-versus-Host Disease
(MDPI, 2022-01-01)
The different cell subsets of the immune system express the vitamin D receptor (VDR). Through the VDR, vitamin D exerts ... |
Article
Mesenchymal Stromal Cells for Treating Steroid-Resistant Acute and Chronic Graft Versus Host Disease: A Multicenter Compassionate Use Experience
(WILEY, 2022-01-01)
Graft versus host disease (GVHD) is a severe complication after allogenic hematopoietic cell transplantation (HSCT). Several ... |
Article
Combined treatment of graft versus host disease using donor regulatory T cells and ruxolitinib
(Nature Publishing Group, 2022-01-01)
Donor derived regulatory T lymphocytes and the JAK1/2 kinase inhibitor ruxolitinib are currently being evaluated as ... |
Article
Cholinergic signals preserve haematopoietic stem cell quiescence during regenerative haematopoiesis
(Nature Publishing Group, 2022-01-01)
The sympathetic nervous system has been evolutionary selected to respond to stress and activates haematopoietic stem cells ... |
| Article |
Article
Phase II Trial of Allogeneic Transplantation Plus Novel Drugs in Multiple Myeloma: Effect of Intensifying Reduced-Intensity Conditioning with Bortezomib and Adding Maintenance Treatment
(Elsevier Inc., 2022-01-01)
The use of reduced-intensity conditioning (RIC) regimens has decreased the risk of nonrelapse mortality (NRM) after ... |
Article
CD4+ and CD8+ T-cell responses in bone marrow to fatty acids in high-fat diets
(Elsevier, 2022-01-01)
Obesity is associated with disruptions in the adaptive immune system; however, dietary fatty acids in high-fat diets (HFDs) ... |
Article
Networking for advanced molecular diagnosis in acute myeloid leukemia patients is possible: the PETHEMA NGS-AML project
(Ferrata Storti Foundation, 2021-12-01)
Next-generation sequencing (NGS) has recently been introduced to efficiently and simultaneously detect genetic variations ... |
Article
Delayed administration of ixazomib modifies the immune response and prevents chronic graft-versus-host disease
(Nature Publishing Group, 2021-09-23)
In this study, we aimed to modify the immune response in the long term after allogeneic bone marrow transplantation ... |
Article
Long-Term Outcomes After Autologous Versus Allogeneic Stem Cell Transplantation in Molecularly-Stratified Patients With Intermediate Cytogenetic Risk Acute Myeloid Leukemia: A PETHEMA Study.
(Elsevier, 2021-01-01)
Acute myeloid leukemia (AML) with intermediate risk cytogenetics (IRcyto) comprises a variety of biological enti- ties ... |
Article
Long-Term Impact of an Educational Antimicrobial Stewardship Program on Management of Patients with Hematological Diseases
(MDPI, 2021-01-01)
Antimicrobial stewardship programs (ASPs) in hematological patients are especially relevant. However, information about ... |
Article
Clinical benefit of glasdegib plus low-dose cytarabine in patients with de novo and secondary acute myeloid leukemia: long-term analysis of a phase II randomized trial
(Springer, 2021-01-01)
This analysis from the phase II BRIGHT AML 1003 trial reports the long-term efficacy and safety of glasdegib + low-dose cytarabine ... |
Article
Upregulation of CD38 expression on multiple myeloma cells by novel HDAC6 inhibitors is a class effect and augments the efficacy of daratumumab
(Nature Publishing Group, 2021-01-01)
Multiple myeloma (MM) is incurable, so there is a significant unmet need for effective therapy for patients with relapsed ... |
Article
T-cells immune response controls the high incidence of adenovirus infection in adult allogenic hematopoietic transplantation recipients
(FERRATA STORTI FOUNDATION, 2021-01-01)
Human adenovirus (HAdV) can produce disseminated disease with high mortality in pediatric allogenic hematopoietic stem ... |
Article
MUFAs in High-Fat Diets Protect against Obesity-Induced Bias of Hematopoietic Cell Lineages
(Wiley, 2021-01-01)
Scope: The role of dietary fatty acids in the generation of bone marrow (BM) immune cells and their trafficking to ... |
Article
Polyphenolic Extract (PE) from Olive Oil Exerts a Potent Immunomodulatory Effect and Prevents Graft-versus-Host Disease in a Mouse Model
(Elsevier, 2020-01-01)
Polyphenols are a group of chemical substances found in plants, with immunomodulatory, antiproliferative, and anti-inflammatory ... |
Article
RIPK1 is a critical modulator of both tonic and TLR-responsive inflammatory and cell death pathways in human macrophage differentiation
(Springer Nature, 2018-01-01)
In this study, we took advantage of human-induced pluripotent stem cells (hiPSC) and CRISPR/Cas9 technology to investigate ... |
Article
Selection of Tumor-Specific Cytotoxic T Lymphocytes in Acute Myeloid Leukemia Patients Through the Identification of T-Cells Capable to Establish Stable Interactions With the Leukemic Cells: “Doublet Technology”
(Frontiers Media, S.A., 2018-01-01)
The relevance of the immune system in cancer has long been studied. Autologous adoptive T cell therapies, based on the use ... |
PhD Thesis
Nuevas modalidades de inmunoprofilaxis en trasplante: Inhibidores del proteosoma
(2017-09-22)
El trasplante alogénico de progenitores hematopoyéticos es una opción potencialmente curativa para numerosos pacientes con ... |
PhD Thesis
 Strategies to obtain tumor-reactive cells for cancer immunotherapy by cell sorting and genetic modifications of T lymphocytes.
(2017-09-05)
Los recientes avances en el campo de la inmunoterapia contra el cáncer han hecho posible que dicha técnica se convierta ... |
| PhD Thesis |
| PhD Thesis |
PhD Thesis
Efecto inmunomodulador de la vitamina D en el periodo postrasplante alogénico de progenitores hematopoyéticos
(2016-01-22)
El presente trabajo de tesis se basa en un ensayo clínico multicéntrico realizado a nivel nacional sobre una población de ... |
Article
Sensitivity of hematopoietic stem cells to mitochondrial dysfunction by SdhD gene deletion
(2016-01-01)
It is established that hematopoietic stem cells (HSC) in the hypoxic bone marrow have adapted their metabolism to ... |
Article
The Dynamics of the Human Leukocyte Antigen Head Domain Modulates Its Recognition by the T-Cell Receptor
(Public Library of Science, 2016-01-01)
Generating the immune response requires the discrimination of peptides presented by the human leukocyte antigen complex ... |
Article
Multivariable time-dependent analysis of the impact of azacitidine in patients with lower-risk myelodysplastic syndrome and unfavorable specific lower-risk score
(Elsevier, 2015-01-01)
Scoring systems for lower-risk myelodysplastic syndrome (LR-MDS) recognize patients with a poorer than expected outcome. ... |
Article
Human Bone Marrow Stromal Cells Differentiate Into Corneal Tissue and Prevent Ocular Graft-Versus-Host Disease in Mice
(SAGE Journals, 2015-01-01)
Clinical trials have assessed the use of human bone marrow stromal cells (hBMSCs) for the treatment of immune-related ... |
PhD Thesis
Cambios en los perfiles de expresión génica en condiciones fisiológicas versus patológicas en el sistema hematopoyético
(2014-12-12)
El trabajo realizado en esta tesis doctoral consiste en el estudio de los cambios en la expresión génica que sufren las ... |
Article
An Active Isodicentric X Chromosome in a Case of Refractory Anaemia with Ring Sideroblasts Associated with Marked Thrombocytosis
(Hindawi, 2014-01-01)
Refractory anaemia with ring sideroblasts and marked thrombocytosis (RARS-T) is a provisional entity in the World Health ... |
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Article
The combination of sirolimus plus tacrolimus improves outcome after reduced-intensity conditioning, unrelated donor hematopoietic stem cell transplantation compared with cyclosporine plus mycofenolate
(Ferrata Storti Foundation, 2013-01-01)
Different types of graft-versus-host disease prophylaxis have been proposed in the setting of reduced intensity and ... |
Article
Differential cytogenetic profile in advanced chronic myeloid leukemia with sequential lymphoblastic and myeloblastic blast crisis
(Elsevier, 2013-01-01)
Frequency of additional chromosomal abnormalities in chronic myeloid leukemia (CML) is estimated to be 7% in chronic phase ... |
Article
Evaluation of prognostic factors among patients with chronic graft-versus-host disease
(Ferrata-Storti Foundation, 2011-01-01)
Background: Chronic graft-versus-host disease (cGVHD) is a major complication after allogeneic stem cell transplantation ... |
