Author profile: Ampuero Herrojo, Javier
Institutional data
Name | Ampuero Herrojo, Javier |
Department | Medicina |
Knowledge area | Medicina |
Professional category | Profesor Contratado Doctor (Plaza Vinc.) |
Request | |
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Statistics
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No. publications
44
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No. visits
3977
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No. downloads
5597
Publications |
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PhD Thesis
![]() Predictores de reingreso precoz en población con cirrosis hepática
(2023-06-26)
La cirrosis hepática es una enfermedad crónica que se asocia a una gran morbi-mortalidad, a menudo con requerimiento de ... |
PhD Thesis
![]() Aplicación clínica de la elastografía por resonancia magnética en la enfermedad hepática crónica
(2023-02-21)
Aims: Aim 1: Comparing the diagnostic accuracy of magnetic resonance elastography (MRE) with ultrasound elastography and ... |
Article
![]() Clinical application of Magnetic resonance elastography in hepatocellular carcinoma: From diagnosis to prognosis
(Elsevier, 2023-01-01)
Hepatocellular carcinoma (HCC) is the most common primary liver cancer and a major public health problem worldwide. Liver ... |
Article
![]() Extracellular Vesicles as Biomarkers in Liver Disease
(MDPI, 2022-12-19)
Extracellular vesicles (EVs) are membrane-derived vesicles released by a variety of cell types, including hepatocytes, ... |
Article
![]() Cardiometabolic characterization in metabolic dysfunction–associated fatty liver disease
(Frontiers Media, 2022-10-20)
Background: To better understand the patient's heterogeneity in fatty liver disease (FLD), metabolic dysfunction–associated ... |
Article
![]() Plasma ammonia levels predict hospitalisation with liver-related complications and mortality in clinically stable outpatients with cirrhosis
(Elsevier, 2022-07-22)
Background & Aims Hyperammonaemia is central in the pathogenesis of hepatic encephalopathy. It also has pleiotropic ... |
Article
![]() Systematic review and meta-analysis: analysis of variables influencing the interpretation of clinical trial results in NAFLD
(SPRINGER, 2022-01-01)
Background NAFLD clinical trials have shown suboptimal results, particularly for liver fibrosis, despite the robust ... |
Article
![]() Glutaminolysis-ammonia-urea Cycle Axis, Non-alcoholic Fatty Liver Disease Progression and Development of Novel Therapies
(XHP Publishing, 2022-01-01)
The prevalence of non-alcoholic fatty liver disease (NAFLD) is increasing worldwide, reflecting the current epidemics of ... |
Article
![]() Metabolic-associated fatty liver disease: From simple steatosis toward liver cirrhosis and potential complications. Proceedings of the Third Translational Hepatology Meeting, organized by the Spanish Association for the Study of the Liver (AEEH)
(Elsevier Doyma, 2022-01-01)
This is a meeting report of the 3rd Translational Hepatology Meeting held in Alicante, Spain, in October 2021. The meeting, ... |
Article
![]() Liver injury in non-alcoholic fatty liver disease is associated with urea cycle enzyme dysregulation
(Nature Publishing Group, 2022-01-01)
The main aim was to evaluate changes in urea cycle enzymes in NAFLD patients and in two preclinical animal models mimicking ... |
Article
![]() General overview about the current management of nonalcoholic fatty liver disease
(ADIS INTERNATIONAL LTD, 2022-01-01)
Nonalcoholic fatty liver disease includes a wide spectrum of manifestations from simple steatosis to nonalcoholic steatohepa ... |
Article
![]() Inhibition of ATG3 ameliorates liver steatosis by increasing mitochondrial function
(Elsevier, 2022-01-01)
Background & Aims: Autophagy-related gene 3 (ATG3) is an enzyme mainly known for its actions in the LC3 lipidation pro ... |
Article
![]() Impact of a Loss-of-Function Variant in HSD17B13 on Hepatic Decompensation and Mortality in Cirrhotic Patients
(MDPI AG, 2022-01-01)
Abstract: A common splice variant in HSD17B13 (rs72613567:TA) was recently found to be associated with a reduced risk of ... |
Article
![]() A Shortcut from Metabolic-Associated Fatty Liver Disease (MAFLD) to Hepatocellular Carcinoma (HCC): c-MYC a Promising Target for Preventative Strategies and Individualized Therapy
(2021-12-31)
Background: Metabolic-associated fatty liver disease (MAFLD) has risen as one of the leading etiologies for hepatocellular ... |
Article
![]() Analysis of Common Pathways and Markers From Non-Alcoholic Fatty Liver Disease to Immune-Mediated Diseases
(Frontiers Media, 2021-11-24)
Metabolic associated fatty liver disease (MAFLD) is the most prevalent form of liver disease worldwide, accounting for a ... |
Article
![]() Wilson's disease: revisiting an old friend
(BAISHIDENG PUBLISHING GROUP INC, 2021-06-27)
Wilson's disease (WD) is a rare condition caused by copper accumulation primarily in the liver and secondly in other organs, ... |
Article
![]() Management of NAFLD patients with advanced fibrosis
(Wiley-Blackwell, 2021-06-21)
The prevalence of non alcoholic fatty liver disease (NAFLD) has increased to 25% in the general population and could double ... |
Article
![]() Definite and indeterminate nonalcoholic steatohepatitis share similar clinical features and prognosis: A longitudinal study of 1893 biopsy-proven nonalcoholic fatty liver disease subjects
(2021-04-01)
Background and Aim: Histological score systems may not fully capture the essential nonalcoholic steatohepatitis (NASH) ... |
Article
![]() Sofosbuvir improves HCV-induced insulin resistance by blocking IRS1 degradation
(WILEY, 2021-01-12)
In the present study, we have demonstrated that sofos buvir (SOF) treatment improves systemic insulin resis tance in ... |
Article
![]() SARS-CoV-2 viral load in nasopharyngeal swabs is not an independent predictor of unfavorable outcome
(NATURE PUBLISHING GROUP, 2021-01-01)
The aim was to assess the ability of nasopharyngeal SARS-CoV-2 viral load at frst patient’s hospital evaluation to predict ... |
Article
![]() Combination of squamous cell carcinoma antigen immunocomplex and alpha-fetoprotein in mid- and long-term prediction of hepatocellular carcinoma among cirrhotic patients
(BAISHIDENG PUBLISHING GROUP INC, 2021-01-01)
BACKGROUND The combination of alpha-fetoprotein (AFP) and squamous cell carcinoma antigen immunocomplex (SCCA-IgM) have ... |
Article
![]() Clinical characteristics and outcome of drug-induced liver injury in the older patients: from the young-old to the oldest-old
(Wiley, 2021-01-01)
Older patients with hepatotoxicity have been scarcely studied in idiosyncratic drug-induced liver injury (DILI) cohorts. ... |
Article
![]() COVID-19 and the liver: the chicken or the egg dilema
(Arán Ediciones, S.L., 2021-01-01)
After the publication of our meta-analysis, in which we demonstrated that aspartate aminotransferase (AST), alanine ... |
Article
![]() Diagnostic accuracy of elastography and magnetic resonance imaging in patients with NAFLD: a systematic review and meta-analysis
(2021-01-01)
Background and Aims: Vibration-controlled transient elastography (VCTE), point shear wave elastography (pSWE), 2- dimensional ... |
Article
![]() An experimental DUAL model of advanced liver damage
(John Wiley & Sons, 2021-01-01)
Individuals exhibiting an intermediate alcohol drinking pattern in conjunction with signs of metabolic risk present clini ... |
Article
![]() Propuesta de nueva denominación: esteatosis hepática metabólica (EHmet)
(Arán Ediciones, S.L., 2021-01-01)
El nombre de una enfermedad no sigue ningún protocolo definido y es habitual la aceptación por parte de la comunidad ... |
Article
![]() Comprehensive analysis and insights gained from long-term experience of the Spanish DILI Registry
(Elsevier Science BV, 2021-01-01)
Background & Aims Prospective drug-induced liver injury (DILI) registries are important sources of information on idiosyncratic ... |
Article
![]() Nonalcoholic fatty liver disease and the risk of metabolic comorbidities: how to manage in clinical practice
(Medycyna Praktyczna, 2020-01-01)
Nonalcoholic fatty liver disease (NAFLD) is a clinical condition that encompasses various forms of liver damage not caused ... |
Article
![]() Stratification of patients in NASH clinical trials: a pitfall for trial success
(Elsevier, 2020-01-01)
Identifying the most effective therapeutic intervention in patients with NAFLD is challenging. Precise stratification in ... |
PhD Thesis
![]() Genes y encefalopatía hepática: propuesta de una huella genética para la valoración del riesgo
(2019-06-06)
Introducción y objetivos: Determinar el impacto de los factores genéticos en el desarrollo de encefalopatía hepática (EH) ... |
Article
![]() Analysis of the burden and variability in the management of NAFLD patients in the clinical practice: unifying the required criteria
(Sociedad Española de Patología Digestiva, 2019-01-01)
Aim: to assess the prevalence of non-alcoholic fatty liver disease (NAFLD) in the gastroenterology outpatient clinic and ... |
Article
![]() Usefulness of bioelectrical impedance analysis for monitoring patients with refractory ascites
(Sociedad Española de Patología Digestiva, 2019-01-01)
Background: bioelectrical impedance analysis is a technique for the determination of the hydropic component. The hydropic ... |
PhD Thesis
![]() Utilidad de la sobrecarga oral de glutamina en la predicción del riesgo y del tipo de encefalopatía hepática.
(2018-12-12)
La encefalopatía hepática (EH) es un síndrome neuropsiquiátrico complejo potencialmente reversible que se produce en ... |
PhD Thesis
![]() El antígeno de células neoplásicas escamosas (SCCA) solo o formando el complejo SCCA-igM es un biomarcador precoz de carcinoma hepatocelular.
(2018-07-11)
Background: Hepatocellular carcinoma (HCC) represents more than 90% of primary liver cancers and is a major health problem. ... |
Article
![]() New therapeutic perspectives in non-alcoholic steatohepatitis
(Elsevier, 2018-02-23)
Management of non-alcoholic steatohepatitis is focused on restitution of metabolic derangement, weight loss and drugs able ... |
Article
![]() Metformin modifies glutamine metabolism in an in vitro and in vivo model of hepatic encephalopathy
(Sociedad Española de Patología Digestiva, 2018-02-01)
Aim: to analyze the effect of metformin on ammonia production derived from glutamine metabolism in vitro and in vivo. Methods: ... |
Article
![]() Simvastatin and metformin inhibit cell growth in hepatitis C virus infected cells via mTOR increasing PTEN and autophagy
(2018-01-31)
Hepatitis C virus (HCV) infection has been related to increased risk of development of hepa tocellular carcinoma (HCC) ... |
Article
![]() Case Report: Acute-on-Chronic Liver Failure: Making the Diagnosis between Infection and Acute Alcoholic Hepatitis
(Thieme Medical Publishers, 2016-06-01)
Acute-on-chronic liver failure (ACLF) represents a reversible syndrome associated with high short-term mortality, characterized ... |
PhD Thesis
![]() ![]() Diabetes mellitus: impact on the pathophysiology, diagnose and treatment of the hepatic encephalopathy.
(2015-01-09)
Encefalopatía hepática La encefalopatía hepática (EH) es un disturbio potencialmente reversible, de causa metabólica, que ... |
Article
![]() Síndrome LPAC secundario a deleción del exón 4 del gen ABCB4 en un paciente con hepatitis C
(Arán Ediciones, S. L., 2014-01-01)
El síndrome LPAC (low-phospholipid-associated cholelithiasis syndrome) está asociado a mutaciones del gen ABCB4, que ... |
Article
![]() Hypoxic hepatitis as diabetic ketoacidosis complication
(Arán Ediciones, S. L., 2014-01-01)
Hypoxic hepatitis (HH) (also known as ischemic hepatitis or shock liver) is characterized by a dramatic but transient ... |
Article
![]() La poliquistosis hepática del adulto (PHA) en España: análisis de una encuesta estructurada analizando la experiencia y actitud de los especialistas de digestivo españoles
(Arán Ediciones, S. L, 2014-01-01)
Antecedentes: la poliquistosis hepática del adulto (PHA) es una enfermedad rara caracterizada por el engrandecimiento ... |
Article |
Article
![]() Metformin inhibits glutaminase activity and protects against hepatic encephalopathy
(2012-01-01)
Aim: To investigate the influence of metformin use on liver dysfunction and hepatic encephalopathy in a retrospective ... |