dc.creator | Noguer, María | es |
dc.creator | Cerezo López, Ana Belén | es |
dc.creator | Moyá Morán, María Luisa | es |
dc.creator | Troncoso González, Ana María | es |
dc.creator | García Parrilla, María del Carmen | es |
dc.date.accessioned | 2017-12-26T15:20:31Z | |
dc.date.available | 2017-12-26T15:20:31Z | |
dc.date.issued | 2014 | |
dc.identifier.citation | Noguer, M., Cerezo López, A.B., Moyá Morán, M.L., Troncoso González, A.M. y García Parrilla, M.d.C. (2014). Synergism Effect between Phenolic Metabolites and Endogenous Antioxidants in Terms of Antioxidant Activity. Advances in Chemical Engineering and Science, 4, 258-265. | |
dc.identifier.uri | http://hdl.handle.net/11441/68011 | |
dc.description.abstract | Polyphenolic compounds, widely distributed in plant kingdom, have been exhaustively studied for their bioactive properties specially antioxidant activity. However, they are extensively metabolized by human organism and the resulting metabolites are largely responsible for their effects. Furthermore, they may interact with the endogenous antioxidant network being this possibility scarcely studied. Plasma antioxidant network encompasses antioxidant enzymes and other substances such as uric acid. In addition, ascorbic acid is the major compound representing water soluble compartment both in foods and human body. The interaction of this vitamin with phenolic compound is largely unexplored. This work aims to study if there is a synergic effect between phenolic metabolites and main antioxidants (uric and ascorbic acid). For this purpose, the antioxidant activity was evaluated in terms of ORAC (oxygen radical absorbance capac
ity) and FRAP (ferricreducing antioxidant power) as these tests involved
either HAT (Hydrogen Atom Transfer) or SET (Single Electron Transfer) mechanisms. Additionally, a kinetic studied was developed to test if the rate constant presented a synergic effect. Protocatechuic acid, 3, 4 -dihydroxyphenylacetic acid, 3,4 -dihydroxyphenylpropionic acid and 3
-hydroxyphenylacetic acid were selected as they were metabolites of polyphenol compounds such as anthocyanins, quercetin, neohesperidin, chlorogenic acid and hesperetin present in wines, orange and strawberries. A synergic effect was proved for the combination of ascorbic acid with 3,4
-dihydroxyphenylacetic acid, both in terms of antioxidant activity and potent increase of velocity of the antioxidant reaction that took place. | es |
dc.description.sponsorship | Ministerio de Economía y Competitividad AGL-2010-22152-C03-01 | es |
dc.format | application/pdf | es |
dc.language.iso | eng | es |
dc.publisher | Universidade Federal do Espírito Santo | es |
dc.relation.ispartof | Advances in Chemical Engineering and Science, 4, 258-265. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Kinetics | es |
dc.subject | Ascorbic Acid | es |
dc.subject | Uric Acid | es |
dc.subject | ORAC | es |
dc.subject | FRAP | es |
dc.title | Synergism Effect between Phenolic Metabolites and Endogenous Antioxidants in Terms of Antioxidant Activity | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Nutrición y Bromatología, Toxicología y Medicina Legal | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Química Física | es |
dc.relation.projectID | AGL-2010-22152-C03-01 | es |
dc.relation.publisherversion | http://dx.doi.org/10.4236/aces.2014.42029 | es |
dc.identifier.doi | 10.4236/aces.2014.42029 | es |
idus.format.extent | 8 p. | es |
dc.journaltitle | Advances in Chemical Engineering and Science | es |
dc.publication.volumen | 4 | es |
dc.publication.initialPage | 258 | es |
dc.publication.endPage | 265 | es |
dc.identifier.sisius | 20798957 | es |
dc.contributor.funder | Ministerio de Economía y Competitividad (MINECO). España | |