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The Gluten-Free Diet: Testing Alternative Cereals Tolerated by Celiac Patients

Opened Access The Gluten-Free Diet: Testing Alternative Cereals Tolerated by Celiac Patients

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Autor: Comino Montilla, Isabel María
Moreno Amador, María de Lourdes
Real, Ana
Rodríguez Herrera, Alfonso
Barro, Francisco
Sousa Martín, Carolina
Departamento: Universidad de Sevilla. Departamento de Microbiología y Parasitología
Fecha: 2013
Publicado en: Nutrients, 5 (10), 4250-4268.
Tipo de documento: Artículo
Resumen: A strict gluten-free diet (GFD) is the only currently available therapeutic treatment for patients with celiac disease, an autoimmune disorder of the small intestine associated with a permanent intolerance to gluten proteins. The complete elimination of gluten proteins contained in cereals from the diet is the key to celiac disease management. However, this generates numerous social and economic repercussions due to the ubiquity of gluten in foods. The research presented in this review focuses on the current status of alternative cereals and pseudocereals and their derivatives obtained by natural selection, breeding programs and transgenic or enzymatic technology, potential tolerated by celiac people. Finally, we describe several strategies for detoxification of dietary gluten. These included enzymatic cleavage of gliadin fragment by Prolyl endopeptidases (PEPs) from different organisms, degradation of toxic peptides by germinating cereal enzymes and transamidation of cereal flours. T...
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Cita: Comino Montilla, I.M., Moreno Amador, M.d.L., Real, A., Rodríguez Herrera, A., Barro, F. y Sousa Martín, C. (2013). The Gluten-Free Diet: Testing Alternative Cereals Tolerated by Celiac Patients. Nutrients, 5 (10), 4250-4268.
Tamaño: 701.5Kb
Formato: PDF

URI: http://hdl.handle.net/11441/41962

DOI: http://dx.doi.org/ 10.3390/nu5104250

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