Author profile: Sousa Martín, Carolina
Institutional data
| Name | Sousa Martín, Carolina |
| Department | Microbiología y Parasitología |
| Knowledge area | Microbiología |
| Professional category | Catedrática de Universidad |
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Statistics
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No. publications
70
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No. visits
16708
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No. downloads
22474
| Publications |
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Article
 An efficient urine peptidomics workflow identifies chemically defined dietary gluten peptides from patients with celiac disease
(Springer Nature, 2022-01-01)
Celiac disease (CeD) is an autoimmune disorder induced by consuming gluten proteins from wheat, barley, and rye. Glutens ... |
Chapter of Book
Celiac Disease, Management, and Follow-Up
(Intechopen, 2022-01-01)
Celiac disease (CD) is a systemic immune-mediated disorder characterized by a specific serological and histological profile ... |
Article
Individual variability in patterns and dynamics of fecal gluten immunogenic peptides excretion after low gluten intake
(Springer, 2022-01-01)
Purpose Determination of Gluten Immunogenic Peptides (GIP) in feces is a direct tool for gluten exposure detection. The ... |
Article
Advances in Celiac Disease and Gluten-Free Diet
(MDPI, 2022-01-01)
|
Article
Consumption of Tritordeum Bread Reduces Immunogenic Gluten Intake without Altering the Gut Microbiota
(Multidisciplinary Digital Publishing Institute (MDPI), 2022-01-01)
Gluten proteins are responsible for the wheat breadmaking quality. However, gluten is also related to human pathologies ... |
Article
Quality of Life in Teenagers and Adults With Coeliac Disease: From Newly Spanish Coeliac Disease Questionnaire Validation to Assessment in a Population-Based Study
(Frontiers Media S.A, 2022-01-01)
Background: Coeliac disease (CD) is an immune-mediated systemic disorder elicited by the ingestion of gluten in genetically ... |
| PhD Thesis |
Article
Food Safety and Cross-Contamination of Gluten-Free Products: A Narrative Review
(MDPI, 2021-07-01)
A gluten-free diet (GFD) is currently the only effective treatment for celiac disease (CD); an individual’s daily intake ... |
PhD Thesis
Nuevas estrategias para el control de la enfermedad celíaca: caracterización de los péptidos imunogénicos del gluten y validación clínica de un biomarcador para el seguimiento del paciente celíaco
(2021-03-19)
La enfermedad celiaca (EC) se define como una enteropatía inflamatoria crónica del intestino delgado causada por la ingesta ... |
Article
Dynamics and Considerations in the Determination of the Excretion of Gluten Immunogenic Peptides in Urine: Individual Variability at Low Gluten Intake
(Multidisciplinary Digital Publishing Institute (MDPI), 2021-01-01)
Background: A lifelong strict gluten-free diet is the only available treatment for celiac disease, but total exclusion of ... |
Article
Rapid, effective, and versatile extraction of gluten in food with application on different immunological methods
(Multidisciplinary Digital Publishing Institute (MDPI), 2021-01-01)
One of the main concerns in gluten analysis is to achieve efficient extraction of gluten proteins. Conventional ethanol-based ... |
Article
Oral consumption of bread from an RNAi wheat line with strongly silenced gliadins elicits no immunogenic response in a pilot study with celiac disease patients
(Multidisciplinary Digital Publishing Institute (MDPI), 2021-01-01)
Celiac disease (CD) is a genetically predisposed, T cell-mediated and autoimmune-like disorder caused by dietary exposure ... |
Article
New insights into non-dietary treatment in celiac disease: Emerging therapeutic options
(Multidisciplinary Digital Publishing Institute (MDPI), 2021-01-01)
To date, the only treatment for celiac disease (CD) consists of a strict lifelong gluten-free diet (GFD), which has numerous ... |
Article
Challenges of monitoring the gluten-free diet adherence in the management and follow-up of patients with celiac disease
(Multidisciplinary Digital Publishing Institute (MDPI), 2021-01-01)
Celiac disease (CD) is a chronic gluten-responsive immune mediated enteropathy and is treated with a gluten-free diet ... |
Article
Determination of gluten immunogenic peptides for the management of the treatment adherence of celiac disease: A systematic review
(Baishideng Publishing Group, 2021-01-01)
BACKGROUND Gluten is a complex mixture of proteins with immunogenic peptide sequences triggering the autoimmune activity ... |
Article
Tritordeum breads are well tolerated with preference over gluten-free breads in non-celiac wheat-sensitive patients and its consumption induce changes in gut bacteria
(Wiley-Blackwell, 2021-01-01)
BACKGROUND: The ingestion of wheat and other cereals are related to several gut disorders. The specific components responsible ... |
Article
Verifying Diagnosis of Refractory Celiac Disease With Urine Gluten Immunogenic Peptides as Biomarker
(Frontiers Media, 2021-01-01)
Refractory celiac disease (RCD) involves T-lymphocyte activation despite supposed absence of gluten exposure. Assessing ... |
Article
Controls and Result Interpretations in Studies of Urine Gluten Peptide Determinations
(Lippincott, 2021-01-01)
|
Final Degree Project
Patologías relacionadas con el consumo de gluten
(2021-01-01)
Las reacciones adversas a los alimentos incluyen las intolerancias y alergias alimentarias, que son un problema creciente ... |
Final Degree Project
Patogenia y epidemiología actualizada del sarampión
(2021-01-01)
El sarampión es una enfermedad viral grave provocada por el virus del sarampión, que afecta mayoritariamente a los niños. ... |
PhD Thesis
Desarrollo de una metodología de aplicación y lectura de parche cutáneo estandarizado para el diagnóstico y manejo de la alergia a las proteínas de la leche de vaca no IgE mediada
(2019-07-19)
El presente trabajo de investigación surgió de la necesidad de la creación de un plan de cuidados protocolizado y estandarizado ... |
Article
Celiac Immunogenic Potential of α-Gliadin Epitope Variants from Triticum and Aegilops Species
(MDPI, 2019-01-01)
The high global demand of wheat and its subsequent consumption arise from the physicochemical properties of bread dough ... |
Article
Stimulatory Response of Celiac Disease Peripheral Blood Mononuclear Cells Induced by RNAi Wheat Lines Differing in Grain Protein Composition
(MDPI, 2019-01-01)
Wheat gluten proteins are responsible for the bread-making properties of the dough but also for triggering important ... |
Article
Prospective longitudinal study: use of faecal gluten immunogenic peptides to monitor children diagnosed with coeliac disease during transition to a gluten‐free diet
(Wiley, 2019-01-01)
Background Treatment for coeliac disease is a lifelong strict gluten‐free diet. Although guidelines recommend regular ... |
Article
A new microbial gluten-degrading prolyl endopeptidase: Potential application in celiac disease to reduce gluten immunogenic peptides
(PLOS, 2019-01-01)
Gluten is a complex of proteins present in barley, wheat, rye and several varieties of oats that triggers celiac disease ... |
Final Degree Project
Papel de la microbiota intestinal en nuestro organismo: una relación de beneficio mutuo
(2018-07-01)
L a microbiota intestinal la componen una amplia variedad de especies de bacterias, hongos virus, arqueas y ... |
Final Degree Project
Tratamientoy monitorización de la enfermedad Celiaca
(2018-07-01)
La enfermedad celíaca (EC) es considerada una patología crónica y sistémica desencadenada por ... |
Final Degree Project
Prevalencia mundial de la enfermedad celíaca
(2018-02-01)
La enfermedad celíaca (EC) se define como una enteropatía inflamatoria crónica del intestino delgado mediada inmunológicamente ... |
Article
Low-gluten, nontransgenic wheat engineered with CRISPR/Cas9
(Wiley Open Access, 2018-01-01)
Coeliac disease is an autoimmune disorder triggered in genetically predisposed individuals by the ingestion of gluten ... |
Article
The Dietary Intervention of Transgenic Low-Gliadin Wheat Bread in Patients with Non-Celiac Gluten Sensitivity (NCGS) Showed No Differences with Gluten Free Diet (GFD) but Provides Better Gut Microbiota Profile
(MDPI, 2018-01-01)
The study evaluated the symptoms, acceptance, and digestibility of bread made from transgenic low-gliadin wheat, in ... |
Article
Gluten Immunogenic Peptides as Standard for the Evaluation of Potential Harmful Prolamin Content in Food and Human Specimen
(MDPI, 2018-01-01)
Gluten is a complex mixture of storage proteins in cereals like wheat, barley, and rye. Prolamins are the main components ... |
Article
Biomarkers to monitor gluten-free diet compliance in celiac patients
(MDPI, 2017-01-01)
Gluten-free diet (GFD) is the only treatment for celiac disease (CD). There is a general consensus that strict GFD adherence ... |
Article
Detection of gluten immunogenic peptides in the urine of patients with coeliac disease reveals transgressions in the gluten-free diet and incomplete mucosal healing
(BMJ Publishing Group, 2017-01-01)
Objective Gluten-free diet (GFD) is the only management for coeliac disease (CD). Available methods to assess GFD compliance ... |
Article
Characterization of celiac disease related oat proteins: bases for the development of high quality oat varieties suitable for celiac patients
(Nature Publishing Group, 2017-01-01)
Some studies have suggested that the immunogenicity of oats depends on the cultivar. RP-HPLC has been proposed as a useful ... |
Article
Targeting of prolamins by RNAi in bread wheat: Effectiveness of seven silencing-fragment combinations for obtaining lines devoid of coeliac disease epitopes from highly immunogenic gliadins
(Wiley-Blackwell, 2016-01-01)
Gluten proteins are responsible for the viscoelastic properties of wheat flour but also for triggering pathologies in ... |
Final Degree Project
Estudio de la adherencia a la dieta sin gluten en pacientes celíacos pediátricos mediante la cuantificación de péptidos inmunogénicos del gluten en heces
(2016-01-01)
La enfermedad celíaca (EC) es un desorden clínico basado en una intolerancia al gluten presente en ciertos cereales como ... |
Final Degree Project
Detección de la fracción inmunotóxica del gluten en diferentes especies de cereales y su implicación en la enfermedad celíaca
(2016-01-01)
La enfermedad celíaca (EC) es una patología que afecta al intestino delgado proximal y está asociada a una intolerancia ... |
Final Degree Project
Actualización epidemiológica de las meningitis de origen bacteriano
(2016-01-01)
La meningitis bacteriana es la forma más común de infecciones supurativas del Sistema Nervioso Central (SNC) y puede estar ... |
Article
Identification and molecular characterization of oat peptides implicated on coeliac immune response
(Co-Action Publishing, 2016-01-01)
Background : Oats provide important nutritional and pharmacological properties, although their safety in coeliac ... |
Article
Fecal Gluten Peptides Reveal Limitations of Serological Tests and Food Questionnaires for Monitoring Gluten-Free Diet in Celiac Disease Patients
(Nature Publishing Group, 2016-01-01)
Objectives: Treatment for celiac disease (CD) is a lifelong strict gluten-free diet (GFD). Patients should be followed-up ... |
PhD Thesis
Caracterización de comunidades microbianas en tumbas etruscas y romanas
(2015-06-30)
El biodeterioro es un problema frecuente en monumentos y en sitios arqueológicos, buen ejemplo de ello es el encontrado ... |
Article
Diversification of the celiac disease α-gliadin complex in wheat: A 33-mer peptide with six overlapping epitopes, evolved following polyploidization
(Wiley-Blackwell, 2015-01-01)
Summary The gluten proteins from wheat, barley and rye are responsible both for celiac disease (CD) and for non-celiac ... |
Article
Role of oats in celiac disease
(Baishideng Publishing Group, 2015-01-01)
A gluten-free diet is currently the only effective means of treating individuals with celiac disease. Such a diet enables ... |
Article
Cereals for developing gluten-free products and analytical tools for gluten detection
(Academic Press, 2014-01-01)
Recently, gluten free foods have attracted much research interest motivated by the increasing market. Despite the motivation ... |
Article
Update on nutritional aspects of gluten-free diet in celiac patients
(Asian Medical Journals, 2014-01-01)
A strict gluten - free diet is the only currently available therapeutic treatment for patients with celiac disease, an ... |
PhD Thesis
Evaluación de la eficacia de tratamientos de desinfesción de suelo en el control de hongos patógenos en el cultivo de la fresa, en las condiciones de cultivo de la provincia de Huelva
(2014-01-01)
El cultivo de la fresa está muy extendido en los cinco continentes, siendo China y Estados Unidos los mayores productores ... |
Article
Reduced-gliadin wheat bread: An alternative to the gluten-free diet for consumers suffering gluten-related pathologies
(Public Library of Science, 2014-01-01)
Wheat flour cannot be tolerated by those who suffer allergies to gluten. Human pathologies associated with grain proteins ... |
Article
Identification and in Vitro reactivity of celiac immunoactive peptides in an apparent gluten-free beer
(Public Library of Science, 2014-01-01)
Gluten content from barley, rye, wheat and in certain oat varieties, must be avoid in individuals with celiac disease. In ... |
Article
Constitutive gut-homing capacity on circulating myeloid dendritic cells in coeliac disease
(Arán Ediciones, S.L., 2014-01-01)
|
Article
Alternative grains as potential raw material for gluten– free food development in the diet of celiac and gluten– sensitive patients
(Austin Publishing Group, 2014-01-01)
Celiac disease is an autoimmune disorder resulting from gluten intolerance and is based on a genetic predisposition. Gluten ... |
Article
The Gluten-Free Diet: Testing Alternative Cereals Tolerated by Celiac Patients
(Multidisciplinary Digital Publishing Institute (MDPI), 2013-01-01)
A strict gluten-free diet (GFD) is the only currently available therapeutic treatment for patients with celiac disease, ... |
| Article |
Patent
Procedimiento para la selección de semillas de cereales aptas para ser consumidas por los enfermos celíacos.
(Oficina Española de Patentes y Marcas , 2012-07-25)
La presente invención se refiere a un procedimiento sencillo para la selección de variedades de semillas de trigo, cebada, ... |
Article
Monitoring of gluten-free diet compliance in celiac patients by assessment of gliadin 33-mer equivalent epitopes in feces
(Oxford University Press, 2012-01-01)
Background: Certain immunotoxic peptides from gluten are resistant to gastrointestinal digestion and can interact with ... |
Article
Molecular and Immunological Characterization of Gluten Proteins Isolated from Oat Cultivars That Differ in Toxicity for Celiac Disease
(Public Library of Science, 2012-01-01)
A strict gluten-free diet (GFD) is the only currently available therapeutic treatment for patients with celiac disease ... |
Article
Diversity in oat potential immunogenicity: basis for the selection of oat varieties with no toxicity in coeliac disease
(BMJ Publishing Group, 2011-01-01)
Background and aims Coeliac disease (CD) is triggered by an abnormal reaction to gluten. Peptides resulting from partially ... |
Article
Different and new Nod factors produced by Rhizobium tropici CIAT899 following Na+ stress
(Oxford University Press, 2009-01-01)
The root nodule bacterium Rhizobium tropici strain CIAT899 is highly stress resistant. It grows under acid conditions, in ... |
Article
A novel plant leucine-rich repeat receptor kinase regulates the response of medicago truncatula roots to salt stress
(American Society of Plant Biologists, 2009-01-01)
In plants, a diverse group of cell surface receptor-like protein kinases (RLKs) plays a fundamental role in sensing external ... |
Article
Toward the Assessment of Food Toxicity for Celiac Patients: Characterization of Monoclonal Antibodies to a Main Immunogenic Gluten Peptide
(Public Library of Science, 2008-01-01)
Background and Aims: Celiac disease is a permanent intolerance to gluten prolamins from wheat, barley, rye and, in some ... |
| PhD Thesis |
Article
Differential expression of the TFIIIA regulatory pathway in response to salt stress between Medicago truncatula genotypes
(American Society of Plant Biologists, 2007-01-01)
Soil salinity is one of the most significant abiotic stresses for crop plants, including legumes. These plants can establish ... |
| PhD Thesis |
| PhD Thesis |
Article
Translational and structural requirements of the early nodulin gene enod40, a short-open reading frame-containing RNA, for elicitation of a cell-specific growth response in the alfalfa root cortex
(American Society for Microbiology, 2001-01-01)
A diversity of mRNAs containing only short open reading frames (sORF-RNAs; encoding less than 30 amino acids) have been ... |
Article
Rational design of a bacterial transcriptional cascade for amplifying gene expression capacity
(Oxford University Press, 2001-01-01)
Cascade regulatory circuits have been described that control numerous cell processes, and may provide models for the design ... |
PhD Thesis
Análisis de los genes de nodulación implicados en la sulfatación de la molécula señal de Rhizobium tropici CIAT899
(2000-04-18)
R.tropici CIAT899 es un simbionte de amplio rango de hospedador capaz de producir nódulos fijadores de nitrógeno en numerosas ... |
| PhD Thesis |
Article
Metalloadsorption by Escherichia coli cells displaying yeast and mammalian metallothioneins anchored to the outer membrane protein LamB
(American Society for Microbiology, 1998-01-01)
Yeast (CUP1) and mammalian (HMT-1A) metallothioneins (MTs) have been efficiently expressed in Escherichia coli as fusions ... |
Article
Effector specificity mutants of the transcriptional activator NahR of naphthalene degrading Pseudomonas define protein sites involved in binding of aromatic inducers
(American Society for Biochemistry and Molecular Biology Inc., 1997-01-01)
This work reports a genetic analysis of the interactions between NahR, the LysR-type regulator of the NAH operons for ... |
PhD Thesis
Introducción de forma estable de genes de la nodulación en el plásmido simbiótico de Rhizobium leguminosarum bv. trifolii RS1051
(1992-12-18)
Una de las técnicas más poderosa usadas en la investigación de Rhizobium es la mutagénesis dirigida descrita por Ruvkun y ... |