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Artículo
Differential expression of THOC1 and ALY mRNP biogenesis/export factors in human cancers
dc.creator | Luna Varo, Rosa María | es |
dc.creator | Japón Rodríguez, Miguel Ángel | es |
dc.creator | Sáez, Carmen | es |
dc.creator | Domínguez Sánchez, María Salud | es |
dc.creator | Aguilera López, Andrés | es |
dc.date.accessioned | 2015-02-27T12:18:29Z | |
dc.date.available | 2015-02-27T12:18:29Z | |
dc.date.issued | 2011 | es |
dc.identifier.citation | Luna Varo, R.M., Japón Rodríguez, M.Á., Sáez, C., Domínguez Sánchez, M.S. y Aguilera López, A. (2011). Differential expression of THOC1 and ALY mRNP biogenesis/export factors in human cancers. BMC Cancer, 77 (11) | |
dc.identifier.issn | 1471-2407 | es |
dc.identifier.other | http://www.biomedcentral.com/content/pdf/1471-2407-11-77.pdf | es |
dc.identifier.uri | http://hdl.handle.net/11441/23048 | |
dc.description.abstract | One key step in gene expression is the biogenesis of mRNA ribonucleoparticle complexes (mRNPs). Formation of the mRNP requires the participation of a number of conserved factors such as the THO complex. THO interacts physically and functionally with the Sub2/UAP56 RNA-dependent ATPase, and the Yra1/REF1/ALY RNA-binding protein linking transcription, mRNA export and genome integrity. Given the link between genome instability and cancer, we have performed a comparative analysis of the expression patterns of THOC1, a THO complex subunit, and ALY in tumor samples. | en |
dc.language.iso | eng | es |
dc.relation.ispartof | BMC Cancer, 77 (11) | |
dc.rights | Atribución-NoComercial-SinDerivadas 4.0 España | es |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0 | es |
dc.title | Differential expression of THOC1 and ALY mRNP biogenesis/export factors in human cancers | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Genética | es |
dc.contributor.affiliation | Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER) | es |
dc.identifier.doi | https://doi.org/10.1186/1471-2407-11-77 | |
dc.journaltitle | BMC Cancer | |
dc.publication.volumen | 77 | |
dc.publication.issue | 11 | |
dc.identifier.idus | https://idus.us.es/xmlui/handle/11441/23048 |
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