Listar Artículos (Química Orgánica) por fecha de publicación
Mostrando ítems 21-40 de 243
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Synthesis of Novel 3-Amino(Hydroxy)methyl-l-fuco-Azafagomines as Leads for Selective Inhibitors of α-l-Fucosidases
(2010)The synthesis of 3-substituted l-fuco-azafagomines from d-lyxose is reported. They represent the first example of ...
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(Pseudo)amide-linked oligosaccharide mimetics: molecular recognition and supramolecular properties
(Beilstein-Institut, 2010)Oligosaccharides are currently recognised as having functions that influence the entire spectrum of cell activities. ...
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Insights in Cellular Uptake Mechanisms of pDNA-polycationic Amphiphilic Cyclodextrin Nanoparticles (CDplexes)
(Elsevier, 2010)It is generally recognized that the major obstacle to efficient gene delivery is cellular internalization and endosomal ...
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Synthesis, characterisation and crystal structure of a three-dimensional network of an h-bonded Ni (II) Hexametylenetetramine complex
(Royal Society of Chemistry, 2010)A three-dimensional network of H-bonding nickel (II) hexamethylenetetramine complex has been synthesized and characterised ...
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Easy Access to Configurationally Controlled C-Glycofuranoside-Based Building Blocks by Means of Formyl C-Glycofuranosides
(2010)A general approach to enantiopure C-glycofuranoside-based hybridα/β-amino acids and nitrones, among other valuable building ...
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Synthesis and Biological Evaluation of Modified 2-Deoxystreptamine Dimers
(Thieme Publishing; Georg Thieme Verlag, 2011)Aminoglycosides are powerful antibiotics, but the emergence of resistant bacterial strains has prompted the search for ...
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Pharmacological chaperone therapy for Gaucher disease: A patent review
(Taylor & Francis, 2011)Introduction: Mutations in the gene encoding for acid β-glucosidase (β-glucocerebrosidase, GlcCerase) are seen in Gaucher ...
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Syntheses and biological activities of 1,4-iminoalditol derivatives as α-L-fucosidase inhibitors
(Schweizerische Chemische Gesellschaft (Swiss Chemistry Society), 2011)A review dealing with 1,4-iminoalditol (hydroxylated pyrrolidine) derivatives as inhibitors of α-l-fucosidases including the different synthetic approaches for their preparation as well as their inhibitory properties is presented.
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Influence of N-donor bases and the solvent in oxodiperoxomolybdenum catalysed olefin epoxidation with hydrogen peroxide in ionic liquids
(Royal Society of Chemistry, 2011)Biphasic catalytic olefin epoxidation systems consisting of oxodiperoxomolybdenum catalysts in 1- n -alkyl-3-methylimidazolium ...
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Alkoxyamine-cyanoborane adducts: Efficient cyanoborane transfer agents
(Royal Society of Chemistry, 2011)We report the synthesis of the hitherto unknown zwitterionic alkoxyamino cyanoboranes by reduction of O-alkyloximes with ...
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Bicyclic (galacto)nojirimycin analogues as glycosidase inhibitors: Effect of structural modifications in their pharmacological chaperone potential towards β-glucocerebrosidase
(Royal Society of Chemistry (Great Britain), 2011)A molecular-diversity-oriented approach for the preparation of bicyclic sp2-iminosugar glycomimetics related to nojirimycin ...
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Total asymmetric synthesis of monosaccharides and analogues
(Schweizerische Chemische Gesellschaft (Swiss Chemistry Society), 2011)Since the discovery of the 'formose reaction' by Butlerow,[1] total synthesis of carbohydrates has undergone rapid ...
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Cyclodextrin-mediated Crystallization of Acid β-glucosidase in Complex with Amphiphilic Bicyclic Nojirimycin Analogues
(Royal Society of Chemistry, 2011)Cyclodextrin-based host-guest chemistry has been exploited to facilitate co-crystallization of recombinant human acid ...
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The nodulation of Alfalfa by the acid-tolerant Rhizobium sp. Strain LPU83 does not require sulfated forms of Lipochitooligosaccharide nodulation signals
(American Society for Microbiology, 2011)The induction of root nodules by the majority of rhizobia has a strict requirement for the secretion of symbiosis-specific ...
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Monosaccharides and Analogues from Simple Achiral Unsaturated Compounds
(Schweizerische Chemische Gesellschaft, 2011)We present herein a selection of ingenious methods that have been developed to convert inexpensive furan, pyrrole and unsaturated hydrocarbons into enantiomerically enriched monosaccharides and analogues of biological interest.
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Nodulation-gene-inducing flavonoids increase overall production of autoinducers and expression of N-acyl homoserine lactone synthesis genes in rhizobia
(2011)Legume-nodulating rhizobia use N-acyl homoserine lactones (AHLs) to regulate several physiological traits related to the ...
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Self-association of a naphthalene-capped-β-cyclodextrin through cooperative strong hydrophobic interactions
(Elsevier, 2011-09-05)NMR, circular dichroism and fluorescence techniques were used to study the structure in solution of a new β-cyclodextrin ...
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Mannosyl-coated nanocomplexes from amphiphilic cyclodextrins and pDNA for site-specific gene delivery
(Elsevier, 2011-10)Fully homogeneous facial amphiphiles consisting in a cyclodextrin (CD) platform onto which a polycationic cluster and a ...