dc.creator | Carullo, Gabriele | es |
dc.creator | Sciubba, Fabio | es |
dc.creator | Governa, Paolo | es |
dc.creator | Mazzotta, Sarah | es |
dc.creator | Frattaruolo, Luca | es |
dc.creator | Grillo, Giorgio | es |
dc.creator | Cappello, Anna Rita | es |
dc.creator | Cravotto, Giancarlo | es |
dc.creator | Cocco, Maria Enrica Di | es |
dc.creator | Aiello, Francesca | es |
dc.date.accessioned | 2020-06-10T15:15:49Z | |
dc.date.available | 2020-06-10T15:15:49Z | |
dc.date.issued | 2020 | |
dc.identifier.citation | Carullo, ., Sciubba, F., Governa, P., Mazzotta, S., Frattaruolo, L., Grillo, G.,...,Aiello, . (2020). Mantonico and Pecorello Grape Seed Extracts: Chemical Characterization and Evaluation of In Vitro Wound-Healing and Anti-Inflammatory Activities. Pharmaceuticals, 13 (5), 1-12. | |
dc.identifier.issn | 1424-8247 | es |
dc.identifier.uri | https://hdl.handle.net/11441/97669 | |
dc.description.abstract | The winemaking process produces a huge number of pomaces that generally are used for energy purposes. Further valuable applications such as health-promoting properties are still under investigation. The seeds of the white berries of Mantonico and Pecorello cv. were extracted in a Soxhlet apparatus, using n-hexane and chloroform as solvents. Extracts were characterized by NMR and GC-MS analyses. They were assayed in vitro as wound healing and anti-inflammatory agents in HaCaT and RAW 264.7 cell lines, respectively. n-hexane Mantonico extract resulted in the most interesting wound healing sample, while n-hexane Pecorello, containing a good number of carotenoids, resulted in a good anti-inflammatory candidate. These preliminary findings underlined the benefit of grape seed extracts valorization due to their health-promoting properties | es |
dc.format | application/pdf | es |
dc.format.extent | 12 p. | es |
dc.language.iso | eng | es |
dc.publisher | MDPI | es |
dc.relation.ispartof | Pharmaceuticals, 13 (5), 1-12. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Soxhlet | es |
dc.subject | grape seeds | es |
dc.subject | wound healing | es |
dc.subject | lipophilic fraction | es |
dc.subject | carotenoids | es |
dc.subject | HaCaT cell line | es |
dc.subject | RAW 264.7 cell line | es |
dc.subject | NMR | es |
dc.subject | GC-MS | es |
dc.title | Mantonico and Pecorello Grape Seed Extracts: Chemical Characterization and Evaluation of In Vitro Wound-Healing and Anti-Inflammatory Activities | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Química Orgánica y Farmacéutica | es |
dc.relation.publisherversion | https://doi.org/10.3390/ph13050097 | es |
dc.identifier.doi | 10.3390/ph13050097 | es |
dc.journaltitle | Pharmaceuticals | es |
dc.publication.volumen | 13 | es |
dc.publication.issue | 5 | es |
dc.publication.initialPage | 1 | es |
dc.publication.endPage | 12 | es |