Artículo
Consensus on the Definition of Advanced Parkinson's Disease: A Neurologists-Based Delphi Study (CEPA Study)
Autor/es | Luquin, MR
Kulisevsky, Jaime Martinez Martin, Pablo Mir Rivera, Pablo Tolosa, Eduardo |
Departamento | Universidad de Sevilla. Departamento de Medicina |
Fecha de publicación | 2017 |
Fecha de depósito | 2020-05-14 |
Publicado en |
|
Resumen | To date, no consensus exists on the key factors for diagnosing advanced Parkinson disease (APD). To obtain consensus on the
definition of APD, we performed a prospective, multicenter, Spanish nationwide, 3-round Delphi ... To date, no consensus exists on the key factors for diagnosing advanced Parkinson disease (APD). To obtain consensus on the definition of APD, we performed a prospective, multicenter, Spanish nationwide, 3-round Delphi study (CEPA study). An ad hoc questionnaire was designed with 33 questions concerning the relevance of several clinical features for APD diagnosis. In the firstround, 240 neurologists of the SpanishMovementDisordersGroup participated in the study.The results obtainedwere incorporated into the questionnaire and both, results and questionnaire, were sent out to and fulfilled by 26 experts in Movement Disorders. Review of results fromthe second-round led to a classification of symptoms as indicative of “definitive,” “probable,” and “possible” APD. This classification was confirmed by 149 previous participating neurologists in a third-round, where 92% completely or very much agreed with the classification. Definitive symptoms of APD included disability requiring help for the activities of daily living, presence of motor fluctuations with limitations to perform basic activities of daily living without help, severe dysphagia, recurrent falls, and dementia. These results will help neurologists to identify some key factors in APD diagnosis, thus allowing users to categorize the patients for a homogeneous recognition of this condition. |
Cita | Luquin, M., Kulisevsky, J., Martinez Martin, P., Mir, P. y Tolosa, E. (2017). Consensus on the Definition of Advanced Parkinson's Disease: A Neurologists-Based Delphi Study (CEPA Study). Parkinson’s Disease, 1-9. |
Ficheros | Tamaño | Formato | Ver | Descripción |
---|---|---|---|---|
Consensus on the Definition of ... | 1.230Mb | [PDF] | Ver/ | |