Trehalose-based Siamese twin amphiphiles with tunable self-assembling, DNA nanocomplexing and gene delivery properties

Carbajo Gordillo, Ana Isabel; Rodríguez Lavado, Julio; Jiménez Blanco, José Luis; Benito Hernández, Juan Manuel; Di Giorgio, Christophe; Vélaz, Itziar; Tros de Ilarduya, Concepción; Ortiz Mellet, Carmen; García Fernández, José Manuel

doi:10.1039/c9cc04489b

Artículo

dc.creator	Carbajo Gordillo, Ana Isabel	es
dc.creator	Rodríguez Lavado, Julio	es
dc.creator	Jiménez Blanco, José Luis	es
dc.creator	Benito Hernández, Juan Manuel	es
dc.creator	Di Giorgio, Christophe	es
dc.creator	Vélaz, Itziar	es
dc.creator	Tros de Ilarduya, Concepción	es
dc.creator	Ortiz Mellet, Carmen	es
dc.creator	García Fernández, José Manuel	es
dc.date.accessioned	2019-09-17T08:47:39Z
dc.date.available	2019-09-17T08:47:39Z
dc.date.issued	2019-06-19
dc.identifier.citation	Carbajo-Gordillo, A.I., Rodríguez Lavado, J., Jiménez Blanco, J.L., Benito Hernández, J.M., Di Giorgio, C., Vélaz, I.,...,García Fernández, J.M. (2019). Trehalose-based Siamese twin amphiphiles with tunable self-assembling, DNA nanocomplexing and gene delivery properties. Chemical Communications, 55 (57), 8227-8230.
dc.identifier.issn	1359-7345	es
dc.identifier.issn	1364-548X	es
dc.identifier.uri	https://hdl.handle.net/11441/89165
dc.description.abstract	An original family of multivalent vectors encompassing gemini and facial amphiphilicity, namely cationic Siamese twin surfactants, has been prepared from the disaccharide trehalose; molecular engineering lets us modulate the self-assembling properties and the topology of the nanocomplexes with plasmid DNA for efficient gene delivery in vitro and in vivo.	es
dc.description.sponsorship	MINECO SAF2016-76083-R CTQ2015- 64425-C2-1-R CTQ2015-64425-C2-2-R RTI2018-097609-B-C21 RTI2018-097609-B-C22	es
dc.description.sponsorship	MCIU SAF2016-76083-R CTQ2015- 64425-C2-1-R CTQ2015-64425-C2-2-R RTI2018-097609-B-C21 RTI2018-097609-B-C22	es
dc.description.sponsorship	Junta de Andalucía FQM2012-1467	es
dc.description.sponsorship	FEDER	es
dc.description.sponsorship	FSE	es
dc.format	application/pdf	es
dc.language.iso	eng	es
dc.publisher	The Society	es
dc.relation.ispartof	Chemical Communications, 55 (57), 8227-8230.
dc.rights	Attribution-NonCommercial-NoDerivatives 4.0 Internacional	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/4.0/	*
dc.subject	Transferencia génica	es
dc.subject	Polietilenimina	es
dc.title	Trehalose-based Siamese twin amphiphiles with tunable self-assembling, DNA nanocomplexing and gene delivery properties	es
dc.type	info:eu-repo/semantics/article	es
dcterms.identifier	https://ror.org/03yxnpp24
dc.type.version	info:eu-repo/semantics/publishedVersion	es
dc.rights.accessRights	info:eu-repo/semantics/openAccess	es
dc.contributor.affiliation	Instituto de Investigaciones Químicas (IIQ) – CIC Cartuja	es
dc.contributor.affiliation	Universidad de Sevilla. Departamento de Química orgánica	es
dc.relation.projectID	SAF2016-76083-R	es
dc.relation.projectID	CTQ2015-64425-C2-1-R	es
dc.relation.projectID	CTQ2015-64425-C2-2-R	es
dc.relation.projectID	RTI2018-097609-B-C21	es
dc.relation.projectID	RTI2018-097609-B-C22	es
dc.relation.projectID	FQM2012-1467	es
dc.relation.publisherversion	http://dx.doi.org/10.1039/c9cc04489b	es
dc.identifier.doi	10.1039/c9cc04489b	es
idus.format.extent	5 p.	es
dc.journaltitle	Chemical Communications	es
dc.publication.volumen	55	es
dc.publication.issue	57	es
dc.publication.initialPage	8227	es
dc.publication.endPage	8230	es

Ficheros	Tamaño	Formato	Ver	Descripción
Trehalose based siamese twin.pdf	3.647Mb	[PDF]	Ver/Abrir

Este registro aparece en las siguientes colecciones

Mostrar el registro sencillo del ítem

Excepto si se señala otra cosa, la licencia del ítem se describe como: Attribution-NonCommercial-NoDerivatives 4.0 Internacional