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  Stereoselective Synthesis of Iminosugar 2-Deoxy(thio)glycosides from Bicyclic Iminoglycal Carbamates Promoted by Cerium(IV) Ammonium Nitrate and Cooperative Brønsted Acid-Type Organocatalysis 

  Herrera González, Irene; Sánchez Fernández, Elena Matilde; Sau, Abhijit; Nativi, Cristina; Garciá Fernández, José M.; Galán, M. Carmen; Ortiz Mellet, Carmen (American Chemical Society, 2020)

  The first examples of iminosugar-type 2-deoxy(thio)glycoside mimetics are reported. The key step is the activation of a ...

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  Catalytic Enantioselective Synthesis of a-aryl a-hydrazino Esters and Amides 

  Velázquez Muñoz, Marta; Alberca Manzano, Saúl; Iglesias Sigüenza, Francisco Javier; Fernández Fernández, Rosario Fátima; Lassaletta, José M; Monge Fernández, David (Royal Society of Chemistry, 2020)

  Catalysts generated by combinations of Pd(TFA)2and pyridine-hydrazone ligands have allowed the asymmetric 1,2-addition of ...

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  AuI-Catalyzed Hydroalkynylation of Haloalkynes 

  García Fernández, Pedro David; Iglesias Sigüenza, Francisco Javier; Rivero Jerez, Paula S.; Díez Martín, Elena; Gómez Bengoa, Enrique; Fernández Fernández, Rosario Fátima; Lassaletta, José M. (American Chemical Society, 2020)

  The AuI-catalyzed reaction between terminal alkynes and aromatic haloalkynes proceeds through divergent pathways depending ...

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  Enantio- and Diastereoselective Nucleophilic Addition of N-tert-Butylhydrazones to Isoquinolinium Ions through Anion-Binding Catalysis 

  Matador Martínez, Esteban; Iglesias Sigüenza, Francisco Javier; Monge Fernández, David; Merino, Pedro; Fernández Fernández, Rosario Fátima; Lassaletta, J. M. (Wiley-Blackwell, 2021)

  A highly enantio- and diastereoselective thiourea-catalyzed dearomatization of isoquinolines employing N-tert-butylhydrazones ...

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  Development of silica‐based biodegradable submicrometric carriers and investigating their characteristics as in vitro delivery vehicles 

  Zyuzin, Mikhail V.; Zhu, Dingcheng; Parak, Wolfgang J.; Feliu, Neus; Escudero Belmonte, Alberto (MDPI, 2020)

  Nanostructured silica (SiO2)-based materials are attractive carriers for the delivery of bioactive compounds into cells. ...

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  Organometallic Nanoparticles Ligated by NHCs: Synthesis, Surface Chemistry and Ligand Effects 

  Cerezo Navarrete, Christian; Lara Muñoz, Patricia; Martínez Prieto, Luis Miguel (MDPI, 2020)

  Over the last 20 years, the use of metallic nanoparticles (MNPs) in catalysis has awakened a great interest in the scientific ...

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  Insights in Cellular Uptake Mechanisms of pDNA-polycationic Amphiphilic Cyclodextrin Nanoparticles (CDplexes) 

  Díaz Moscoso, Alejandro; Vercauteren, Dries; Rejman, Joanna; Benito, Juan M.; Ortiz Mellet, Carmen; De Smedt, Stefaan C.; Fernández, José M. García (Elsevier, 2010)

  It is generally recognized that the major obstacle to efficient gene delivery is cellular internalization and endosomal ...

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  Alkoxyamine-cyanoborane adducts: Efficient cyanoborane transfer agents 

  Márquez, José M.; Martínez Castro, Elisa; Gabrielli, Serena; López López, Óscar; Maya Castilla, Inés; Angulo, Manuel; Álvarez, Eleuterio; Fernández-Bolaños Guzmán, José María (Royal Society of Chemistry, 2011)

  We report the synthesis of the hitherto unknown zwitterionic alkoxyamino cyanoboranes by reduction of O-alkyloximes with ...

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  Pharmacological chaperone therapy for Gaucher disease: A patent review 

  Benito, Juan M.; García Fernández, José M.; Ortiz Mellet, Carmen (Taylor & Francis, 2011)

  Introduction: Mutations in the gene encoding for acid β-glucosidase (β-glucocerebrosidase, GlcCerase) are seen in Gaucher ...

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  Enhanced Gene Delivery Triggered by Dual pH/Redox Responsive Host-Guest Dimerization of Cyclooligosaccharide Star Polycations 

  Carbajo Gordillo, Ana Isabel; López Fernández, José; Benito, Juan M.; Jiménez Blanco, José Luis; Santana Armas, María L.; Marcelo, Gema; Ortiz Mellet, Carmen; García Fernández, José M. (Wiley, 2022)

  A robust strategy is reported to build perfectly monodisperse star polycationscombining a trehalose-based cyclooligosaccharide ...

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  Cyclodextrin-mediated Crystallization of Acid β-glucosidase in Complex with Amphiphilic Bicyclic Nojirimycin Analogues 

  Brumshtein, Boris; Aguilar Moncayo, Matilde; Benito, Juan M.; García Fernández, José M.; Silman, Israel; Shaaltiel, Yoseph; Aviezer, David; Sussman, Joel L.; Futerman, Anthony H.; Ortiz Mellet, Carmen (Royal Society of Chemistry, 2011)

  Cyclodextrin-based host-guest chemistry has been exploited to facilitate co-crystallization of recombinant human acid ...

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  Axially Chiral Triazoloisoquinolin-3-ylidene Ligands in Gold(I)-catalyzed Asymmetric Intermolecular (4 + 2) Cycloadditions of Allenamides and Dienes 

  Francos, Javier; Grande Carmona, Francisca; Faustino, Hélio; Iglesias Sigüenza, Francisco Javier; Díez Martín, Elena; Alonso, Isaac; Fernández Fernández, Rosario Fátima; Lassaletta, José M.; López, Fernando; Mascareñas, José L. (American Chemical Society, 2012)

  The first highly enantioselective intermolecular (4 + 2) cycloaddition between allenes and dienes is reported. The reaction ...

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  Inhibition of Type 1 Fimbriae-mediated Escherichia Coli Adhesion and Biofilm Formation by Trimeric Cluster Thiomannosides Conjugated to Diamond Nanoparticles 

  Khanal, Manakamana; Larsonneur, Fanny; Raks, Victoriia; Barras, Alexandre; Baumann, Jean-Sébastien; Martin, Fernando Ariel; Martin, Fernando Ariel; Boukherroub, Rabah; Ghigo, Jean Marc; Ortiz Mellet, Carmen; Zaitsev, Vladimir; Garcia Fernandez, Jose M.; Beloin, Christophe; Siriwardena, Aloysius; Szunerits, Sabine (Royal Society of Chemistry, 2015)

  Recent advances in nanotechnology have seen the development of a number of microbiocidal and/or anti-adhesive nanoparticles ...

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  Pyridine–hydrazone ligands in enantioselective palladium-catalyzed Suzuki–Miyaura cross-couplings 

  Álvarez Casao, Yolanda; Estepa, Beatriz; Monge Fernández, David; Ros, Abel; Iglesias Sigüenza, Francisco Javier; Álvarez, Eleuterio; Fernández Fernández, Rosario Fátima; Lassaletta, José M. (Elsevier, 2016)

  The geometries and coordination properties of modular pyridineehydrazone N,N-ligands containing C2- symmetric ...

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  Reduction of N2O with hydrosilanes catalysed by RuSNS nanoparticles 

  Molinillo, Pablo; Lacroix, Bertrand; Vattier Lagarrigue, María Florencia; Rendón Márquez, Nuria; Suárez, Andrés; Lara Muñoz, Patricia (Royal Society of Chemistry, 2022)

  A series of RuSNS nanoparticles, prepared by decomposition of Ru(COD)(COT) with H2 in the presence of an SNS ligand, have been found to catalyse the reduction of the greenhouse gas N2O to N2 employing different hydrosilanes.

• Article
  

  Helical donor–acceptor platinum complexes displaying dual luminescence and near-infrared circularly polarized luminescence 

  Vázquez Domínguez, Pablo; Journaud, Océane; Vanthuyne, Nicolas; Jacquemin, Denis; Favereau, Ludovic; Crassous, Jeanne; Ros Lao, Abel (Royal Society of Chemistry, 2021)

  A series of chiral platina[5]helicenes displaying dual luminescence, i.e., fluorescence between 450 and 600 nm and red/NIR ...

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  sp2-Iminosugars targeting human lysosomal β-hexosaminidase as pharmacological chaperone candidates for late-onset Tay-Sachs disease 

  González Cuesta, Manuel; Herrera González, Irene; García Moreno, M. Isabel; Ashmus, Roger A.; Vocadlo, David J.; García Fernández, José M.; Nanba, Eiji; Higaki, Katsumi; Ortiz Mellet, Carmen (Taylor & Francis, 2022)

  The late-onset form of Tay-Sachs disease displays when the activity levels of human β-hexosaminidase A (HexA) fall below ...

• Article
  

  Hydrogenation of an iridium-coordinated imidazol-2-ylidene ligand fragment 

  Hernández Juárez, Martín; López Serrano, Joaquín; González Herrero, P.; Rendón Márquez, Nuria; Álvarez González, Eleuterio; Paneque Sosa, Margarita; Suárez Escobar, Andrés Luis (Royal Society of Chemistry, 2018)

  An iridium complex featuring a metalated lutidine-derived CNP ligand reacts with KOt Bu to yield a dimeric species with ...

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  Hydroboration of carbon dioxide with catechol- and pinacolborane using an Ir–CNP* pincer complex. Water influence on the catalytic activity 

  Sánchez Mellado, Práxedes; Hernández Juárez, Martín; Rendón Márquez, Nuria; López Serrano, Joaquín; Álvarez González, Eleuterio; Paneque Sosa, Margarita; Suárez Escobar, Andrés Luis (Royal Society of Chemistry, 2018)

  Iridium complexes based on deprotonated lutidine-derived CNP* pincers 2a/2b selectively catalyzed the hydroboration of ...

• Article
  

  Molecular bottom-up approaches for the synthesis of inorganic and hybrid nanostructures 

  Escudero Belmonte, Alberto; Carrillo Carrión, Carolina; Romero Ben, Elena; Franco, Ana; Rosales Barrios, Christian; Castillejos Anguiano, María del Carmen; Khiar, Noureddine (Multidisciplinary Digital Publishing Institute (MDPI), 2021)

  Chemical routes for the synthesis of nanostructures are fundamental in nanoscience. Among the different strategies for the ...

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