Presentation
A Tracking Algorithm For Cell Motility Assays in CMOS Systems
Author/s | Martínez Gómez, Cristina
Olmo Fernández, Alberto ![]() ![]() ![]() ![]() ![]() ![]() ![]() Huertas Sánchez, Gloria ![]() ![]() ![]() ![]() ![]() ![]() ![]() Pérez García, Pablo ![]() ![]() ![]() ![]() ![]() ![]() ![]() Maldonado-Jacobi, Andrés Yúfera García, Alberto ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
Department | Universidad de Sevilla. Departamento de Tecnología Electrónica Universidad de Sevilla. Departamento de Electrónica y Electromagnetismo |
Publication Date | 2017 |
Deposit Date | 2018-06-13 |
Published in |
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ISBN/ISSN | 978-1-5090-2809-2 1557-170X |
Abstract | This work proposes a method for the study and
real-time monitoring of a single cell on a 2D electrode matrix,
of great interest in cell motility assays and in the
characterization of cancer cell metastasis. A CMOS ... This work proposes a method for the study and real-time monitoring of a single cell on a 2D electrode matrix, of great interest in cell motility assays and in the characterization of cancer cell metastasis. A CMOS system proposal for cell location based on occupation maps data generated from Electrical Cell-substrate Impedance Spectroscopy (ECIS) has been developed. From experimental assays data, an algorithm based on the analysis of the eight nearest neighbours has been implemented to find the cell center of mass. The path followed by a cell, proposing a Brownian route, has been simulated with the proposed algorithm. The presented results give an accuracy over 95% in the determination of the coordinates (x, y) from the expected cell center of mass. |
Funding agencies | Ministerio de Economía y Competitividad (MINECO). España |
Project ID. | TEC2013-46242-C3-1-P
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Citation | Martínez Gómez, C., Olmo Fernández, A., Huertas Sánchez, G., Pérez García, P., Maldonado Jacobi, A. y Yúfera García, A. (2017). A Tracking Algorithm For Cell Motility Assays in CMOS Systems. En EMBC 2017: 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (837-840), Seogwipo, South Korea: IEEE Computer Society. |
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