dc.creator | Moreno Clavijo, Elena | es |
dc.creator | Carmona Asenjo, Ana Teresa | es |
dc.creator | Moreno Vargas, Antonio José | es |
dc.creator | Álvarez González, Eleuterio | es |
dc.creator | Robina Ramírez, Inmaculada | es |
dc.date.accessioned | 2018-02-09T15:46:29Z | |
dc.date.available | 2018-02-09T15:46:29Z | |
dc.date.issued | 2010 | |
dc.identifier.citation | Moreno Clavijo, E., Carmona Asenjo, A.T., Moreno Vargas, A.J., Álvarez, E. y Robina Ramírez, I. (2010). Synthesis of Novel 3-Amino(Hydroxy)methyl-l-fuco-Azafagomines as Leads for Selective Inhibitors of α-l-Fucosidases. Synlett, 9, 1367-1370. | |
dc.identifier.issn | 0936-5214 | es |
dc.identifier.issn | 1437-2096 (electrónico) | es |
dc.identifier.uri | https://hdl.handle.net/11441/70186 | |
dc.description.abstract | The synthesis of 3-substituted l-fuco-azafagomines from d-lyxose is reported. They represent the first example of aza-C-glycosides having a biimino (-NH-NH-) moiety. The key step of the synthesis is the introduction of the hydrazine moiety by reductive hydrazination of a 1-deoxy-ketohexose with tert-butyl carbazate. Their glycosidase inhibitory properties are also reported. | es |
dc.description.sponsorship | Ministerio de Ciencia e Innovación of Spain CTQ2008-01565/BQU | es |
dc.description.sponsorship | Junta de Andalucía FQM-345 and P07-FQM-03056 | es |
dc.format | application/pdf | es |
dc.language.iso | eng | es |
dc.relation.ispartof | Synlett, 9, 1367-1370. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Azasugars | es |
dc.subject | Glycosidases | es |
dc.subject | Fucosidase inhibitors | es |
dc.subject | Aza-fagomines | es |
dc.subject | C-glycosides | es |
dc.title | Synthesis of Novel 3-Amino(Hydroxy)methyl-l-fuco-Azafagomines as Leads for Selective Inhibitors of α-l-Fucosidases | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Química orgánica | es |
dc.relation.publisherversion | http://dx.doi.org/10.1055/s-0029-1219906 | es |
dc.identifier.doi | 10.1055/s-0029-1219906 | es |
idus.format.extent | 4 | es |
dc.journaltitle | Synlett | es |
dc.publication.issue | 9 | es |
dc.publication.initialPage | 1367 | es |
dc.publication.endPage | 1370 | es |
dc.contributor.funder | Ministerio de Ciencia e Innovación (MICIN). España | |
dc.contributor.funder | Junta de Andalucía | |