Article
Speed matters: How subtle changes in DNA end resection rate affect repair
dc.creator | Huertas Sánchez, Pablo | es |
dc.creator | Cruz García, Andrés | es |
dc.date.accessioned | 2017-03-21T13:59:41Z | |
dc.date.available | 2017-03-21T13:59:41Z | |
dc.date.issued | 2015 | |
dc.identifier.citation | Huertas Sánchez, P. y Cruz García, A. (2015). Speed matters: How subtle changes in DNA end resection rate affect repair. Molecular & cellular oncology, 2 (3), e982964-1-e982964-3. | |
dc.identifier.issn | 2372-3556 | es |
dc.identifier.uri | http://hdl.handle.net/11441/56082 | |
dc.description.abstract | The contribution of BRCA1 (breast cancer 1) to the repair of broken DNA is well established, but its real role at the molecular level is less well understood. By developing a new high-resolution, single-molecule technique, we have now shown that BRCA1 accelerates the processing of DNA breaks that subsequently engage in homologous recombination. | es |
dc.description.sponsorship | España, Ministerio de Economía y Competitividad, SAF2010-14877 | es |
dc.format | application/pdf | es |
dc.language.iso | eng | es |
dc.publisher | Taylor & Francis | es |
dc.relation.ispartof | Molecular & cellular oncology, 2 (3), e982964-1-e982964-3. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | BRCA1 | es |
dc.subject | CtIP | es |
dc.subject | DNA end resection | es |
dc.subject | DNA repair/recombination | es |
dc.title | Speed matters: How subtle changes in DNA end resection rate affect repair | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Genética | es |
dc.relation.projectID | info:eu-repo/grantAgreement/MINECO/SAF2010-14877 | es |
dc.identifier.doi | 10.4161/23723556.2014.982964 | es |
idus.format.extent | 3 p. | es |
dc.journaltitle | Molecular & cellular oncology | es |
dc.publication.volumen | 2 | es |
dc.publication.issue | 3 | es |
dc.publication.initialPage | e982964-1 | es |
dc.publication.endPage | e982964-3 | es |
dc.contributor.funder | Ministerio de Economía y Competitividad (MINECO). España |
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pub45kmco-02-03-982964.pdf | 111.1Kb | [PDF] | View/ | |