Speed matters: How subtle changes in DNA end resection rate affect repair

Huertas Sánchez, Pablo; Cruz García, Andrés

doi:10.4161/23723556.2014.982964

Artículo

dc.creator	Huertas Sánchez, Pablo	es
dc.creator	Cruz García, Andrés	es
dc.date.accessioned	2017-03-21T13:59:41Z
dc.date.available	2017-03-21T13:59:41Z
dc.date.issued	2015
dc.identifier.citation	Huertas Sánchez, P. y Cruz García, A. (2015). Speed matters: How subtle changes in DNA end resection rate affect repair. Molecular & cellular oncology, 2 (3), e982964-1-e982964-3.
dc.identifier.issn	2372-3556	es
dc.identifier.uri	http://hdl.handle.net/11441/56082
dc.description.abstract	The contribution of BRCA1 (breast cancer 1) to the repair of broken DNA is well established, but its real role at the molecular level is less well understood. By developing a new high-resolution, single-molecule technique, we have now shown that BRCA1 accelerates the processing of DNA breaks that subsequently engage in homologous recombination.	es
dc.description.sponsorship	España, Ministerio de Economía y Competitividad, SAF2010-14877	es
dc.format	application/pdf	es
dc.language.iso	eng	es
dc.publisher	Taylor & Francis	es
dc.relation.ispartof	Molecular & cellular oncology, 2 (3), e982964-1-e982964-3.
dc.rights	Attribution-NonCommercial-NoDerivatives 4.0 Internacional	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/4.0/	*
dc.subject	BRCA1	es
dc.subject	CtIP	es
dc.subject	DNA end resection	es
dc.subject	DNA repair/recombination	es
dc.title	Speed matters: How subtle changes in DNA end resection rate affect repair	es
dc.type	info:eu-repo/semantics/article	es
dcterms.identifier	https://ror.org/03yxnpp24
dc.type.version	info:eu-repo/semantics/publishedVersion	es
dc.rights.accessRights	info:eu-repo/semantics/openAccess	es
dc.contributor.affiliation	Universidad de Sevilla. Departamento de Genética	es
dc.relation.projectID	info:eu-repo/grantAgreement/MINECO/SAF2010-14877	es
dc.identifier.doi	10.4161/23723556.2014.982964	es
idus.format.extent	3 p.	es
dc.journaltitle	Molecular & cellular oncology	es
dc.publication.volumen	2	es
dc.publication.issue	3	es
dc.publication.initialPage	e982964-1	es
dc.publication.endPage	e982964-3	es
dc.contributor.funder	Ministerio de Economía y Competitividad (MINECO). España

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