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Artículo
Cylindrospermopsin-microcystin-LR combinations may induce genotoxic and histopathological damage in rats
(Multidisciplinary Digital Publishing Institute (MDPI), 2020)
Cylindrospermopsin (CYN) and microcystins (MC) are cyanotoxins that can occur simultaneously in contaminated water and food. CYN/MC-LR mixtures previously investigated in vitro showed an induction of micronucleus (MN) ...
Artículo
In vivo genotoxicity evaluation of cylindrospermopsin in rats using a combined micronucleus and comet assay
(Elsevier, 2019)
Cylindrospermopsin (CYN) is a potent cyanotoxin recognized as an emerging human threat due to its cytotoxicity and potential carcinogenicity. Although the genotoxicity of CYN has been extensively studied in vitro, limited ...
Artículo
Mutagenic and genotoxic potential of pure Cylindrospermopsin by a battery of in vitro tests
(Elsevier, 2018)
Cylindrospermopsin (CYN) is a cyanobacterial toxin with an increasing world-wide occurrence. The main route of human exposure is through the ingestion of contaminated food and water. The European Food Safety Authority has ...
Artículo
In vitro toxicological assessment of an organosulfur compound from Allium extract: Cytotoxicity, mutagenicity and genotoxicity studies
(Elsevier, 2017)
Garlic (Allium sativum) and onion (Allium cepa) are being used in the food industry as flavoring but also for their antimicrobial activities. These activities are mainly derived from the organosulfur compounds (OSCs). ...
Artículo
Genotoxicity Evaluation of Propyl-Propane-Thiosulfinate (PTS) from Allium genus Essential Oils by a Combination of Micronucleus and Comet Assays in Rats
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
Propyl-propanethiosulfinate (PTS) is a component of Allium essential oils. This organosulfur molecule can be used as a feed additive to decrease the appearance of bacterial resistances caused by the residues of antibiotics. ...