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Mostrando ítems 1-10 de 20
Artículo
Evaluation of toxic effects induced by repeated exposure to Cylindrospermopsin in rats using a 28-day feeding study
(Elsevier, 2021-05)
Cylindrospermopsin (CYN) is a toxin with a world-wide increasing occurrence. It can induce toxic effects both in humans and the environment, and toxicity studies are needed to complete its toxicological profile. In this ...
Artículo
Effect of cold food storage techniques on the contents of Microcystins and Cylindrospermopsin in leaves of spinach (Spinacia oleracea) and lettuce (Lactuca sativa)
(Elsevier, 2022-11-06)
The presence of Cylindrospermopsin (CYN) and Microcystins (MCs) in vegetables is considered as a significant worldwide toxicological risk. Thus, this work aims to assess for the first time the impact of refrigeration (4 ...
Artículo
Cylindrospermopsin-microcystin-LR combinations may induce genotoxic and histopathological damage in rats
(Multidisciplinary Digital Publishing Institute (MDPI), 2020)
Cylindrospermopsin (CYN) and microcystins (MC) are cyanotoxins that can occur simultaneously in contaminated water and food. CYN/MC-LR mixtures previously investigated in vitro showed an induction of micronucleus (MN) ...
Artículo
Immunomodulatory Effects of Pure Cylindrospermopsin in Rats Orally Exposed for 28 Days
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)
Cylindrospermopsin (CYN) is a ubiquitous cyanotoxin showing increasing incidence worldwide. CYN has been classified as a cytotoxin and, among its toxic effects, its immunotoxicity is scarcely studied. This work investigates ...
Artículo
In Vitro Mutagenic and Genotoxic Assessment of Anatoxin-a Alone and in Combination with Cylindrospermopsin
(MDPI, 2023)
Anatoxin-a (ATX-a) is a cyanobacterial toxin whose occurrence has been reported worldwide and has attracted increasing scientific interest due to its toxicity. Moreover, in nature, ATX-a usually appears together with other ...
Tesis Doctoral
Implicaciones en seguridad alimentaria derivadas de la exposición a cilindrospermopsina y microcistinas: evaluación toxicológica
(2021-04-20)
En la actualidad, como consecuencia del cambio climático, la eutrofización de las aguas y el desarrollo de actividades antropogénicas, se está produciendo un aumento en la frecuencia y presencia de floraciones de cianobacterias ...
Artículo
In vivo genotoxicity evaluation of cylindrospermopsin in rats using a combined micronucleus and comet assay
(Elsevier, 2019)
Cylindrospermopsin (CYN) is a potent cyanotoxin recognized as an emerging human threat due to its cytotoxicity and potential carcinogenicity. Although the genotoxicity of CYN has been extensively studied in vitro, limited ...
Artículo
Impact of Gastrointestinal Digestion In Vitro Procedure on the Characterization and Cytotoxicity of Reduced Graphene Oxide
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)
The growing interest in graphene derivatives is a result of their variety of applications in many fields. Due to their use, the oral route could be a potential way of entrance for the general population. This work assesses ...
Artículo
Influence of refrigeration and freezing in Microcystins and Cylindrospermopsin concentrations on fish muscle of tilapia (Oreochromis niloticus) and tench (Tinca tinca)
(Elsevier, 2021)
The consumption of fish contaminated with cyanotoxins is an important public health issue due to their potential adverse effects. The aim of this study was to assess the influence of refrigeration (4 °C) and freezing (−20 ...
Artículo
Jornadas de divulgación científica: Aportaciones de la Toxicología en la investigación de la seguridad de las sustancias y para la sociedad
(Real e Ilustre Colegio Oficial de Farmacéuticos de Sevilla, 2023)
Las “Jornadas de divulgación científica: Aportaciones de la Toxicología en la investigación de la seguridad de las sustancias y para la sociedad” se celebraron el 19 de mayo de 2023 en la Facultad de Farmacia de la Universidad ...