dc.creator | Ontanilla-Clavijo, Guillermo | es |
dc.creator | Praena Segovia, Julia | es |
dc.creator | Giráldez Gallego, Álvaro | es |
dc.creator | Cordero Matia, María Elisa | es |
dc.creator | Sousa Martín, José Manuel | es |
dc.date.accessioned | 2024-05-21T16:09:14Z | |
dc.date.available | 2024-05-21T16:09:14Z | |
dc.date.issued | 2017 | |
dc.identifier.citation | Ontanilla-Clavijo, G., Praena Segovia, J., Giráldez Gallego, Á., Cordero Matia, M.E. y Sousa Martín, J.M. (2017). Severe acute hepatitis and cold agglutinin-related hemolytic anemia secondary to prime infection with Epstein-Barr virus. Revista Española de Enfermedades Digestivas, 109 (5), 388-390. https://doi.org/10.17235/reed.2017.4072/2015. | |
dc.identifier.issn | 1130-0108 | es |
dc.identifier.issn | 2340-4167 | es |
dc.identifier.uri | https://hdl.handle.net/11441/158771 | |
dc.description.abstract | Epstein-Barr virus, a member of the Herpesviridae family, is
responsible for the infectious mononucleosis clinical syndrome,
which mainly includes the pharyngitis, fever, and lymphadenopathy
triad after incubation for 30-50 days. The liver is involved in 80-90%
of patients in a self-limiting transient manner, with jaundice being
much more uncommon (5%). From a hematological standpoint it
may manifest aplastic anemia, neutropenia, and thrombocytopenia.
We report a case of infectious mononucleosis that included severe
acute hepatitis and was associated with severe hemolytic anemia
secondary to cold agglutinins. After exclusion of other etiologies, and
given the clinical suspicion of the above association, which was later
confirmed by lab tests, empiric therapy was initiated with antiviral
agents (aciclovir + valganciclovir) and corticoids, which resulted
in a progressive clinical improvement until complete remission.
Therefore, we believe that this case report will reinforce the clinical
evidence in support of the above combined therapy for serious
infectious mononucleosis as a step prior to liver transplantation. | es |
dc.format | application/pdf | es |
dc.format.extent | 3 p. | es |
dc.language.iso | eng | es |
dc.publisher | Aran Ediciones S.A. | es |
dc.relation.ispartof | Revista Española de Enfermedades Digestivas, 109 (5), 388-390. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Epstein-Barr virus | es |
dc.subject | Acute hepatitis | es |
dc.subject | Hemolytic anemia | es |
dc.title | Severe acute hepatitis and cold agglutinin-related hemolytic anemia secondary to prime infection with Epstein-Barr virus | es |
dc.type | info:eu-repo/semantics/article | es |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Medicina | es |
dc.relation.publisherversion | https://www.reed.es/severe-acute-hepatitis-and-cold-agglutinin-related-hemolytic-anemia-secondary-to-prime-infection-with-epstein-barr-virus942 | es |
dc.identifier.doi | 10.17235/reed.2017.4072/2015 | es |
dc.contributor.group | Universidad de Sevilla. CTS203 : Estudio de las enfermedades infecciosas | es |
dc.journaltitle | Revista Española de Enfermedades Digestivas | es |
dc.publication.volumen | 109 | es |
dc.publication.issue | 5 | es |
dc.publication.initialPage | 388 | es |
dc.publication.endPage | 390 | es |