dc.creator | Medrano, Mayte | es |
dc.creator | Carrillo-Cruz, Estrella | es |
dc.creator | Montero, Isabel | es |
dc.creator | Pérez Simón, José Antonio | es |
dc.date.accessioned | 2024-05-06T12:46:20Z | |
dc.date.available | 2024-05-06T12:46:20Z | |
dc.date.issued | 2018-09-08 | |
dc.identifier.citation | Medrano, M., Carrillo-Cruz, E., Montero, I. y Pérez Simón, J.A. (2018). Vitamin D: Effect on Haematopoiesis and Immune System and Clinical Applications. International Journal of Molecular Sciences, 19 (9), 2663. https://doi.org/10.3390/ijms19092663. | |
dc.identifier.issn | 1422-0067 | es |
dc.identifier.uri | https://hdl.handle.net/11441/157704 | |
dc.description.abstract | Vitamin D is a steroid-like hormone which acts by binding to vitamin D receptor (VDR).
It plays a main role in the calcium homeostasis and metabolism. In addition, vitamin D display
other important effects called “non-classical actions.” Among them, vitamin D regulates immune
cells function and hematopoietic cells differentiation and proliferation. Based on these effects, it is
currently being evaluated for the treatment of hematologic malignancies. In addition, vitamin D
levels have been correlated with patients’ outcome after allogeneic stem cell transplantation, where it
might regulate immune response and, accordingly, might influence the risk of graft-versus-host
disease. Here, we present recent advances regarding its clinical applications both in the treatment of
hematologic malignancies and in the transplant setting. | es |
dc.format | application/pdf | es |
dc.format.extent | 25 p. | es |
dc.language.iso | eng | es |
dc.publisher | MDPI | es |
dc.relation.ispartof | International Journal of Molecular Sciences, 19 (9), 2663. | |
dc.rights | Atribución 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | Vitamin D | es |
dc.subject | Haematopoiesis | es |
dc.subject | Leukaemia | es |
dc.subject | Myelodysplastic syndrome | es |
dc.subject | Allogeneic stem cell transplantation | es |
dc.title | Vitamin D: Effect on Haematopoiesis and Immune System and Clinical Applications | es |
dc.type | info:eu-repo/semantics/article | es |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Medicina | es |
dc.contributor.affiliation | Instituto de Biomedicina de Sevilla (IBIS) | |
dc.relation.projectID | PI17/02177 | es |
dc.relation.publisherversion | https://www.mdpi.com/1422-0067/19/9/2663 | es |
dc.identifier.doi | 10.3390/ijms19092663 | es |
dc.journaltitle | International Journal of Molecular Sciences | es |
dc.publication.volumen | 19 | es |
dc.publication.issue | 9 | es |
dc.publication.initialPage | 2663 | es |
dc.contributor.funder | Instituto de Carlos III-FEDER | es |