dc.creator | Santos García, Diego | es |
dc.creator | de Deus Fonticoba, Teresa | es |
dc.creator | Cores, Carlos | es |
dc.creator | Suárez Castro, Ester | es |
dc.creator | Hernández Vara, Jorge | es |
dc.creator | Jesús, Silvia | es |
dc.creator | Mir Rivera, Pablo | es |
dc.creator | Martínez-Martín, Pablo | es |
dc.date.accessioned | 2024-02-07T14:29:15Z | |
dc.date.available | 2024-02-07T14:29:15Z | |
dc.date.issued | 2023 | |
dc.identifier.citation | Santos García, D., de Deus Fonticoba, T., Cores, C., Suárez Castro, E., Hernández Vara, J., Jesús, S.,...,Martínez-Martín, P. (2023). Falls predict acute hospitalization in Parkinson's disease. Journal Of Parkinsons Disease, 13 (1), 105-124. https://doi.org/10.3233/JPD-212539. | |
dc.identifier.issn | 1877-7171 | es |
dc.identifier.uri | https://hdl.handle.net/11441/154836 | |
dc.description.abstract | Background: There is a need for identifying risk factors for hospitalization in Parkinson’s disease (PD) and also interventions
to reduce acute hospital admission.
Objective: To analyze the frequency, causes, and predictors of acute hospitalization (AH) in PD patients from a Spanish
cohort.
Methods: PD patients recruited from 35 centers of Spain from the COPPADIS-2015 (COhort of Patients with PArkinson’s
DIsease in Spain, 2015) cohort from January 2016 to November 2017, were included in the study. In order to identify
predictors of AH, Kaplan-Meier estimates of factors considered as potential predictors were obtained and Cox regression
performed on time to hospital encounter 1-year after the baseline visit.
Results: Thirty-five out of 605 (5.8%) PD patients (62.5 ± 8.9 years old; 59.8% males) presented an AH during the 1-year
follow-up after the baseline visit. Traumatic falls represented the most frequent cause of admission, being 23.7% of all
acute hospitalizations. To suffer from motor fluctuations (HR [hazard ratio] 2.461; 95% CI, 1.065–5.678; p = 0.035), a very
severe non-motor symptoms burden (HR [hazard ratio] 2.828; 95% CI, 1.319–6.063; p = 0.008), falls (HR 3.966; 95% CI
1.757–8.470; p = 0.001), and dysphagia (HR 2.356; 95% CI 1.124–4.941; p = 0.023) was associated with AH after adjustment
to age, gender, disease duration, levodopa equivalent daily dose, total number of non-antiparkinsonian drugs, and UPDRS-IIIOFF. Of the previous variables, only falls (HR 2.998; 95% CI 1.080–8.322; p = 0.035) was an independent predictor of AH.
Conclusion: Falls is an independent predictor of AH in PD patients. | es |
dc.format | application/pdf | es |
dc.format.extent | 20 p. | es |
dc.language.iso | eng | es |
dc.publisher | IOS Press | es |
dc.relation.ispartof | Journal Of Parkinsons Disease, 13 (1), 105-124. | |
dc.rights | Atribución-NoComercial 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/ | * |
dc.subject | Falls | es |
dc.subject | Hospitalization | es |
dc.subject | Parkinson’s disease | es |
dc.subject | Predictors | es |
dc.title | Falls predict acute hospitalization in Parkinson's disease | es |
dc.type | info:eu-repo/semantics/article | es |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Instituto de Biomedicina de Sevilla (IBIS) | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Medicina | es |
dc.relation.publisherversion | https://content.iospress.com/articles/journal-of-parkinsons-disease/jpd212539 | es |
dc.identifier.doi | 10.3233/JPD-212539 | es |
dc.journaltitle | Journal Of Parkinsons Disease | es |
dc.publication.volumen | 13 | es |
dc.publication.issue | 1 | es |
dc.publication.initialPage | 105 | es |
dc.publication.endPage | 124 | es |