Mostrar el registro sencillo del ítem
Artículo
Advantages and Disadvantages of Apoptosis in the Aging Process
dc.creator | Argüelles Castilla, Sandro | es |
dc.creator | Guerrero Castilla, Angélica | es |
dc.creator | Cano Rodríguez, María Mercedes | es |
dc.creator | Muñoz Pinto, Mario Faustino | es |
dc.creator | Ayala Gómez, Antonio | es |
dc.date.accessioned | 2024-01-26T17:56:03Z | |
dc.date.available | 2024-01-26T17:56:03Z | |
dc.date.issued | 2019 | |
dc.identifier.citation | Argüelles Castilla, S., Guerrero Castilla, A., Cano Rodríguez, M.M., Muñoz Pinto, M.F. y Ayala Gómez, A. (2019). Advantages and Disadvantages of Apoptosis in the Aging Process. Annals of the New York Academy of Sciences, 1443 (1), 20-33. https://doi.org/10.1111/nyas.14020. | |
dc.identifier.issn | 0077-8923 | es |
dc.identifier.issn | 1749-6632 | es |
dc.identifier.uri | https://hdl.handle.net/11441/154096 | |
dc.description.abstract | Researchers cannot predict as yet how long a human being can live. Life expectancy has been steadily increasing in the last century, but perhaps not always the quality of life in parallel with it. Future generations will be faced with the problems of an increased life expectancy along with the emergence of new age-related diseases. A deeper understanding of the aging process is crucial to ameliorate, if not to prevent, these projected new old-age diseases. One of the mechanisms responsible for healthy aging is through the effective maintenance of physiological, biochemical, and immunological functions. To carry this out, the organism needs to create new cells to replace old ones and to induce the disappearance of old and damaged cells. Apoptosis is involved in all these processes. However, if apoptosis is dysregulated, premature senescence-associated diseases are likely to appear. In our review, the focus will be on a better understanding of the role of apoptosis in the aging process. These signaling pathways will most assuredly be pharmacologically targeted in antiaging medicine therapies. | es |
dc.description.sponsorship | Universidad de Sevilla USE-14793-G | es |
dc.format | application/pdf | es |
dc.format.extent | 19 p. | es |
dc.language.iso | eng | es |
dc.publisher | Wiley-Blackwell | es |
dc.relation.ispartof | Annals of the New York Academy of Sciences, 1443 (1), 20-33. | |
dc.subject | Aging | es |
dc.subject | Apoptosis | es |
dc.subject | Inflammation | es |
dc.subject | Oxidative stress | es |
dc.subject | Senescence | es |
dc.title | Advantages and Disadvantages of Apoptosis in the Aging Process | es |
dc.type | info:eu-repo/semantics/article | es |
dc.type.version | info:eu-repo/semantics/acceptedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Bioquímica y Biología Molecular | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Fisiología | es |
dc.relation.projectID | USE-14793-G | es |
dc.relation.publisherversion | https://dx.doi.org/10.1111/nyas.14020 | es |
dc.identifier.doi | 10.1111/nyas.14020 | es |
dc.journaltitle | Annals of the New York Academy of Sciences | es |
dc.publication.volumen | 1443 | es |
dc.publication.issue | 1 | es |
dc.publication.initialPage | 20 | es |
dc.publication.endPage | 33 | es |
dc.contributor.funder | Universidad de Sevilla | es |
Ficheros | Tamaño | Formato | Ver | Descripción |
---|---|---|---|---|
Advantages and disadvantages.pdf | 906.5Kb | ![]() | Ver/ | |
Este registro aparece en las siguientes colecciones
Este documento está protegido por los derechos de propiedad intelectual e industrial. Sin perjuicio de las exenciones legales existentes, queda prohibida su reproducción, distribución, comunicación pública o transformación sin la autorización del titular de los derechos, a menos que se indique lo contrario.