• Article
  

  Targeting Protein Kinase C in Glioblastoma Treatment 

  Geribaldi Doldán, Noelia; Hervás Corpión, Irati; Gómez Oliva, Ricardo; Domínguez García, Samuel; Ruiz, Felix A.; Iglesias Lozano, Irene; Carrascal Moreno, María Livia; Nuñez Abades, Pedro Antonio (MDPI, 2021)

  Glioblastoma (GBM) is the most frequent and aggressive primary brain tumor and is associated with a poor prognosis. Despite ...

• Article
  

  Age-Dependent Vulnerability to Oxidative Stress of Postnatal Rat Pyramidal Motor Cortex Neurons 

  Carrascal Moreno, María Livia; Gorton, Ella; Pardillo Díaz, Ricardo; Pérez García, Patricia; Gómez Oliva, Ricardo; Nuñez Abades, Pedro Antonio (MDPI, 2020-12)

  Oxidative stress is one of the main proposed mechanisms involved in neuronal degeneration. To evaluate the consequences ...

• Article
  

  Neuroprotective Effect of Vascular Endothelial Growth Factor on Motoneurons of the Oculomotor System 

  Silva Hucha, Silvia; Pastor Loro, Ángel Manuel; Morcuende Fernández, Sara R. (MDPI, 2021-01)

  Vascular endothelial growth factor (VEGF) was initially characterized as a potent angiogenic factor based on its activity ...

• Article
  

  Evolution of Experimental Models in the Study of Glioblastoma: Toward Finding Efficient Treatments 

  Gómez Oliva, Ricardo; Domínguez García, Samuel; Carrascal Moreno, María Livia; Pardillo Díaz, Ricardo; Verástegui, Cristina; Castro, Carmen; Núñez Abades, Pedro Antonio; Geribaldi Doldán, Noelia (Frontiers Media, 2021)

  Glioblastoma (GBM) is the most common form of brain tumor characterized by its resistance to conventional therapies, ...

• Article
  

  Effect of Age and Lipoperoxidation in Rat and Human Adipose Tissue-Derived Stem Cells 

  Muñoz Pinto, Mario Faustino; Argüelles Castilla, Sandro; Marotta, Francesco; Barbagallo, M.; Cano Rodríguez, María Mercedes; Ayala Gómez, Antonio (Hindawi, 2020)

  A wide range of clinical applications in regenerative medicine were opened decades ago with the discovery of adult stem ...

• Article
  

  Purinergic Receptor Blockade with Suramin Increases Survival of Postnatal Neural Progenitor Cells In Vitro 

  Herrera Lira, Alejandro; Morcuende Fernández, Sara R.; Talaverón Aguilocho, Rocío; Benítez Temiño, Beatriz; Pastor Loro, Ángel Manuel; Rodríguez Matarredona, Esperanza (MDPI, 2021)

  Neural progenitor cells (NPCs) are self-renewing and multipotent cells that persist in the postnatal and adult brain in ...

• Article
  

  Connexin43 Region 266–283, via Src Inhibition, Reduces Neural Progenitor Cell Proliferation Promoted by EGF and FGF-2 and Increases Astrocytic Differentiation 

  Talaverón Aguilocho, Rocío; Rodríguez Matarredona, Esperanza; Herrera Lira, Alejandro; Medina, José M.; Tabernero, Arantxa (2020)

  Neural progenitor cells (NPCs) are self-renewing cells that give rise to the major cells in the nervous system and are ...

• Article
  

  Retinoprotective Effect of Wild Olive (Acebuche) Oil-Enriched Diet against Ocular Oxidative Stress Induced by Arterial Hypertension 

  Santana Garrido, Álvaro; Reyes Goya, Claudia; Pérez-Camino, María del Carmen; André, Helder; Mate Barrero, Alfonso; Vázquez Cueto, Carmen María (MDPI, 2020)

  Oxidative stress plays an important role in the pathogenesis of ocular diseases, including hypertensive eye diseases. The ...

• Article
  

  Nitric oxide and pH modulation in gynaecological cancer 

  Sanhueza, Carlos; Araos, Joaquín D.; Naranjo, Luciano; Barros, Eric; Subiabre, Mario; Toledo, Fernando; Gutiérrez, Jaime Agustín; Chiarello, Delia Indira; Pardo, Fabián N.; Leiva, Andrea; Sobrevia Luarte, Luis (Wiley-Blackwell, 2016)

  Nitric oxide plays several roles in cellular physiology, including control of the vascular tone and defence against pathogen ...

• Article
  

  Sodium/proton exchanger isoform 1 regulates intracellular pH and cell proliferation in human ovarian cancer 

  Sanhueza, Carlos; Araos, Joaquín D.; Naranjo, Luciano; Toledo, F.; Beltrán, Ana Rosa; Ramírez, Marco Antonio; Gutiérrez, Jaime Agustín; Pardo, Fabián N.; Leiva, Andrea; Sobrevia Luarte, Luis (Elsevier, 2017)

  Cancer cells generate protons (H+) that are extruded to the extracellular medium mainly via the Na+/H+ exchanger 1 (NHE1), ...

• Article
  

  Mechanism of vascular toxicity in rats subjected to treatment with a tyrosine kinase inhibitor 

  Reyes Goya, Claudia; Santana Garrido, Álvaro; Soto Astacio, Estefanía; Aramburu Bodas, Oscar; Zambrano, Sonia; Mate Barrero, Alfonso; Vázquez Cueto, Carmen María (Multidisciplinary Digital Publishing Institute (MDPI), 2020)

  Sunitinib (Su) is a tyrosine kinase inhibitor with antiangiogenic and antineoplastic effects that is recommended therapy ...

• Article
  

  Targeting mTORs by omega-3 fatty acids: a possible novel therapeutic strategy for neurodegeneration? 

  Shirooie, Samira; Nabavi, Seyed Fazel; Dehpour, Ahmad R.; Belwal, Tarun; Habtemariam, Solomon; Argüelles Castilla, Sandro; Nabavi, Seyed Mohammad (Elsevier, 2018-09)

  Neurodegenerative diseases (NDs) such as Parkinson's (PD), Alzheimer's (AD), Huntington's disease (HD), and amyotrophic ...

• Article
  

  Hialuronic acid in sking aging 

  Serres, José; Cano Rodríguez, María Mercedes; Muñoz Pinto, Mario Faustino; Argüelles Castilla, Sandro; Ayala Gómez, Antonio (Spanish Society of Anti-Aging Medicine and Longevity, 2016-10)
• Article
  

  Physical exercise and myokines 

  Zumárraga Franco, Javier; Argüelles Castilla, Sandro; Ayala Gómez, Antonio; Cano Rodríguez, María Mercedes (Spanish Society of Anti-Aging Medicine and Longevity, 2019-10)

  Among the types of muscles present in the body is skeletal muscle, which is the one that allows the development of ...

• Article
  

  A novel PKC activating molecule promotes neuroblast differentiation and delivery of newborn neurons in brain injuries 

  Domínguez García, Samuel; Geribaldi Doldán, Noelia; Gómez Oliva, Ricardo; Ruiz, Felix A.; Carrascal Moreno, María Livia; Bolívar, Jorge; Verástegui, Cristina; García Alloza, Mónica; Macías Sánchez, Antonio J.; Hernández Galán, Rosario; Nuñez Abades, Pedro Antonio (Springer Nature, 2020)

  Neural stem cells are activated within neurogenic niches in response to brain injuries. This results in the production of ...

• Article
  

  Structural and molecular characteristics of axons in the long head of the biceps tendon 

  Blumer, Roland; Boesmueller, Sandra E.; Gesslbauer, Bernhard; Hirtler, Lena; Candel Bormann, Daniel; Pastor Loro, Ángel Manuel; Streicher, Johannes; Mittermayr, Rainer (Springer Nature, 2020)

  The innervation of the long head of the biceps tendon (LHBT) is not sufficiently documented. This is a drawback since ...

• Article
  

  Na+-H+ exchange activity in brush-border membrane vesicles isolated from chick small intestine 

  Ferrero, María Isabel; Cano Rodríguez, María Mercedes; Ilundáin Larrañeta, María Anunciación Ana (Elsevier, 1995)

  This study was undertaken to investigate the presence of a Na+{single bond}H+ antiporter in brush-border membrane vesicles ...

• Article
  

  Na+-dependent D-mannose transport at the apical membrane of rat small intestine and kidney cortex 

  Horra Padilla, Carmen de la; Cano Rodríguez, María Mercedes; Peral Rubio, María José; García Delgado, Marta; Durán Martínez, Juan Manuel; Calonge Castrillo, María Luisa; Ilundáin Larrañeta, María Anunciación Ana (Elsevier, 2001)

  The presence of a Na+/D-mannose cotransport activity in brush-border membrane vesicles (BBMV), isolated from either rat ...

• Article
  

  D-mannose transport and metabolism in isolated enterocytes 

  Durán Martínez, Juan Manuel; Cano Rodríguez, María Mercedes; Peral Rubio, María José; Ilundáin Larrañeta, María Anunciación Ana (Oxford University Press, 2004)

  D-mannose transport and metabolism has been studied in enterocytes isolated from chicken small intestine. In the presence ...

• Article
  

  Na+-dependent and Na+-independent betaine transport across the apical membrane of rat renal epithelium 

  Cano Rodríguez, María Mercedes; Calonge Castrillo, María Luisa; Ilundáin Larrañeta, María Anunciación Ana (Elsevier, 2015)

  The low renal excretion of betaine indicates that the kidney efficiently reabsorbs the betaine filtered by the glomeruli ...

View more