Artículos (Fisiología)
Recent Submissions
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Article
Hypertension secondary to nitric oxide depletion produces oxidative imbalance and inflammatory/fibrotic outcomes in the cornea of C57BL/6 mice.
(Springer, 2022)Arterial hypertension (AH) leads to oxidative and infammatory imbalance that contribute to fbrosis development in many target ...
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Eye Movements But Not Vision Drive the Development of Palisade Endings
(Association for Research in Vision and Ophthalmology, 2022)PURPOSE. To test whether visual experience and/or eye movements drive the postnatal development of palisade endings in ...
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Controlled attenuation parameter-insulin resistance (CIR) score to predict non-alcoholic steatohepatitis
(Nature Research, 2022-12-19)The diagnosis of non-alcoholic steatohepatitis (NASH) requires liver biopsy. Patients with NASH are at risk of progression ...
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Palmitoylation regulates neuropilin-2 localization and function in cortical neurons and conveys specificity to semaphorin signaling via palmitoyl acyltransferases.
(eLife Sciences Publications, 2023)Secreted semaphorin 3F (Sema3F) and semaphorin 3A (Sema3A) exhibit remarkably distinct effects on deep layer excitatory ...
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Proprioceptors in extraocular muscles
(Wiley-Blackwell, 2023)New Findings: What is the topic of this review? This review aims to evaluate the literature on proprioceptors and particular ...
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Manipulation of Amino Acid Levels with Artificial Diets Induces a Marked Anticancer Activity in Mice with Renal Cell Carcinoma
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)Targeted therapies with antiangiogenic drugs (e.g., sunitinib) and immune checkpoint inhibitors (e.g., anti-PD-1 antibodies) ...
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Histological Methods to Assess Skeletal Muscle Degeneration and Regeneration in Duchenne Muscular Dystrophy
(MDPI, 2022)Duchenne muscular dystrophy (DMD) is a progressive disease caused by the loss of function of the protein dystrophin. This ...
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Inhibiting the inflammasome with MCC950 counteracts muscle pyroptosis and improves Duchenne muscular dystrophy
(Frontiers Media, 2022)Background: Duchenne muscular dystrophy (DMD) is the most common inherited human myopathy. Typically, the secondary process ...
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Altered Cortical Palmitoylation Induces Widespread Molecular Disturbances in Parkinson’s Disease
(MDPI, 2022)The relationship between Parkinson’s disease (PD), the second-most common neurodegenerative disease after Alzheimer’s ...
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Article
Reelin Protects against Colon Pathology via p53 and May Be a Biomarker for Colon Cancer Progression
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)Previous observations made in human and mouse colons suggest that reelin protects the colon from pathology. In this study, ...
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Spinal cord from body donors is suitable for multicolor immunofluorescence
(Springer Nature, 2022)Immunohistochemistry is a powerful tool for studying neuronal tissue from humans at the molecular level. Obtaining fresh ...
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Oxidative Stress as a Potential Mechanism Underlying Membrane Hyperexcitability in Neurodegenerative Diseases
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)Neurodegenerative diseases are characterized by gradually progressive, selective loss of anatomically or physiologically ...
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Oxidative and Inflammatory Imbalance in Placenta and Kidney of sFlt1-Induced Early-Onset Preeclampsia Rat Model
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)Preeclampsia (PE) is a pregnancy-specific disorder characterized by the new onset of hypertension plus proteinuria and/or ...
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Article
Similar incidence of coronavirus disease 2019 (COVID-19) in patients with rheumatic diseases with and without hydroxychloroquine therapy
(Public Library of Science, 2021)Background Hydroxychloroquine is not efficacious as post-exposure prophylaxis against coronavirus disease 2019 (COVID-19). ...
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Acute Colon Inflammation Triggers Primary Motor Cortex Glial Activation, Neuroinflammation, Neuronal Hyperexcitability, and Motor Coordination Deficits
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)Neuroinflammation underlies neurodegenerative diseases. Herein, we test whether acute colon inflammation activates microglia ...
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A Single Intraventricular Injection of VEGF Leads to Long-Term Neurotrophic Effects in Axotomized Motoneurons
(Society for Neuroscience, 2020)Vascular endothelial growth factor (VEGF) has been recently demonstrated to induce neuroprotective and synaptotrophic ...
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Increased novelty-induced locomotion, sensitivity to amphetamine, and extracellular dopamine in striatum of Zdhhc15-deficient mice
(Springer Nature, 2021)Novelty-seeking behaviors and impulsivity are personality traits associated with several psychiatric illnesses including ...
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Evaluation of aquaporins in the cerebrospinal fluid in patients with idiopathic normal pressure hydrocephalus
(PLOS, 2021)Brain aquaporin 1 (AQP1) and AQP4 are involved in cerebrospinal fluid (CSF) homeostasis and might participate in the origin ...
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Article
The Neurokinin-1 Receptor Is Essential for the Viability of Human Glioma Cells: A Possible Target for Treating Glioblastoma
(Hindawi, 2022)Background. Glioblastoma or glioma is the most common malignant brain tumor. Patients have a prognosis of approximately ...
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Article
Palisade endings have an exocytotic machinery but lack acetylcholine receptors and distinct acetylcholinesterase activity
(ARVO, 2020)Purpose: The purpose of this work was to test whether palisade endings express structural and molecular features of ...