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  Hypertension secondary to nitric oxide depletion produces oxidative imbalance and inflammatory/fibrotic outcomes in the cornea of C57BL/6 mice. 

  Santana Garrido, Álvaro; Reyes Goya, Claudia; Arroyo Barrios, Ana María; Andre, Helder; Vázquez Cueto, Carmen María; Mate Barrero, Alfonso (Springer, 2022)

  Arterial hypertension (AH) leads to oxidative and infammatory imbalance that contribute to fbrosis development in many target ...

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  Eye Movements But Not Vision Drive the Development of Palisade Endings 

  Carrero Rojas, Génova; Martín Calvo, Paula; Lischka, Thomas; Streicher, Johannes; Rodríguez de la Cruz, Rosa María; Pastor Loro, Ángel Manuel; Blumer, Roland (Association for Research in Vision and Ophthalmology, 2022)

  PURPOSE. To test whether visual experience and/or eye movements drive the postnatal development of palisade endings in ...

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  Controlled attenuation parameter-insulin resistance (CIR) score to predict non-alcoholic steatohepatitis 

  Macías Sánchez, Juan; Parra Membrives, Pablo; Sosa Moreno, Francisco; Rincón, Pilar; Martínez Baena, Darío; Fernández Fuertes, Marta; Lorente Herce, José Manuel; Martínez, Rafael C.; Jiménez Riera, Águeda Granada; Corma Gómez, Anaïs; González-Serna Martín, Manuel Alejandro; Pineda Vergara, Juan Antonio; Real, Luis Miguel (Nature Research, 2022-12-19)

  The diagnosis of non-alcoholic steatohepatitis (NASH) requires liver biopsy. Patients with NASH are at risk of progression ...

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  Palmitoylation regulates neuropilin-2 localization and function in cortical neurons and conveys specificity to semaphorin signaling via palmitoyl acyltransferases. 

  Koropouli, Eleftheria; Wang, Qiang; Mejías Estévez, Rebeca María; Hand, Randal; Wang, Tao; Ginty, David D.; Kolodkin, Alex L. (eLife Sciences Publications, 2023)

  Secreted semaphorin 3F (Sema3F) and semaphorin 3A (Sema3A) exhibit remarkably distinct effects on deep layer excitatory ...

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  Proprioceptors in extraocular muscles 

  Blumer, Roland; Carrero Rojas, Génova; Martín Calvo, Paula; Streicher, Johannes; Rodríguez de la Cruz, Rosa María; Pastor Loro, Ángel Manuel (Wiley-Blackwell, 2023)

  New Findings: What is the topic of this review? This review aims to evaluate the literature on proprioceptors and particular ...

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  Manipulation of Amino Acid Levels with Artificial Diets Induces a Marked Anticancer Activity in Mice with Renal Cell Carcinoma 

  Calderón Montaño, José Manuel; Guillén Mancina, Emilio; Jiménez Alonso, Julio José; Jiménez González, Víctor; Burgos Morón, Estefanía; Mate Barrero, Alfonso; Pérez Guerrero, María Concepción; López Lázaro, Miguel (Multidisciplinary Digital Publishing Institute (MDPI), 2022)

  Targeted therapies with antiangiogenic drugs (e.g., sunitinib) and immune checkpoint inhibitors (e.g., anti-PD-1 antibodies) ...

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  Histological Methods to Assess Skeletal Muscle Degeneration and Regeneration in Duchenne Muscular Dystrophy 

  Dubuisson, Nicolas; Versele, Romain; Planchon, Chloé; Selvais, Camille M.; Noel, Laurence; Davis López de Carrizosa, María América (MDPI, 2022)

  Duchenne muscular dystrophy (DMD) is a progressive disease caused by the loss of function of the protein dystrophin. This ...

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  Inhibiting the inflammasome with MCC950 counteracts muscle pyroptosis and improves Duchenne muscular dystrophy 

  Dubuisson, Nicolas; Davis López de Carrizosa, María América; Versele, Romain; Selvais, Camille M.; Noel, Laurence; Van den Bergh, P. Y. D.; Brichard, Sonia M.; Abou-Samra, Michel (Frontiers Media, 2022)

  Background: Duchenne muscular dystrophy (DMD) is the most common inherited human myopathy. Typically, the secondary process ...

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  Altered Cortical Palmitoylation Induces Widespread Molecular Disturbances in Parkinson’s Disease 

  Cervilla-Martínez, Juan F.; Rodríguez Gotor, Juan J.; Wypijewski, Krzysztof J.; Fontán Lozano, Ángela del Carmen; Wang, Tao; Santamaria, Enrique; Fuller, William; Mejías Estévez, Rebeca María (MDPI, 2022)

  The relationship between Parkinson’s disease (PD), the second-most common neurodegenerative disease after Alzheimer’s ...

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  Reelin Protects against Colon Pathology via p53 and May Be a Biomarker for Colon Cancer Progression 

  Serrano Morales, José Manuel; Vázquez Carretero, María Dolores; García Miranda, Pablo; Carvajal Vázquez, Ana Eloisa; Calonge Castrillo, María Luisa; Ilundáin Larrañeta, María Anunciación Ana; Peral Rubio, María José (Multidisciplinary Digital Publishing Institute (MDPI), 2022)

  Previous observations made in human and mouse colons suggest that reelin protects the colon from pathology. In this study, ...

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  Spinal cord from body donors is suitable for multicolor immunofluorescence 

  Reissig, L. F.; Carrero Rojas, Génova; Maierhofer, U.; Moghaddam, A. S.; Hainfellner, A.; Gesslbauer, Bernhard; Haider, T.; Streicher, Johannes; Aszmann, O. C.; Pastor Loro, Ángel Manuel; Weninger, W. J.; Blumer, Roland (Springer Nature, 2022)

  Immunohistochemistry is a powerful tool for studying neuronal tissue from humans at the molecular level. Obtaining fresh ...

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  Oxidative Stress as a Potential Mechanism Underlying Membrane Hyperexcitability in Neurodegenerative Diseases 

  Pardillo Díaz, Ricardo; Pérez García, Patricia; Castro, Carmen; Núñez Abades, Pedro Antonio; Carrascal Moreno, María Livia (Multidisciplinary Digital Publishing Institute (MDPI), 2022)

  Neurodegenerative diseases are characterized by gradually progressive, selective loss of anatomically or physiologically ...

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  Oxidative and Inflammatory Imbalance in Placenta and Kidney of sFlt1-Induced Early-Onset Preeclampsia Rat Model 

  Santana Garrido, Álvaro; Reyes Goya, Claudia; Espinosa Martín, Pablo; Sobrevia Luarte, Luis; Beltrán Romero, Luis Matías; Vázquez Cueto, Carmen María; Mate Barrero, Alfonso (Multidisciplinary Digital Publishing Institute (MDPI), 2022)

  Preeclampsia (PE) is a pregnancy-specific disorder characterized by the new onset of hypertension plus proteinuria and/or ...

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  Similar incidence of coronavirus disease 2019 (COVID-19) in patients with rheumatic diseases with and without hydroxychloroquine therapy 

  Macías Sánchez, Juan; González Moreno, Paz; Sánchez García, Esther; Morillo Verdugo, Ramón Alejandro; Pérez Venegas, José J.; Pinilla, Ana; Macho, M. Mar; Martínez, M. Victoria; González-Serna Martín, Manuel Alejandro; Corma, Anaïs; Real, Luis M.; Pineda Vergara, Juan Antonio (Public Library of Science, 2021)

  Background Hydroxychloroquine is not efficacious as post-exposure prophylaxis against coronavirus disease 2019 (COVID-19). ...

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  Acute Colon Inflammation Triggers Primary Motor Cortex Glial Activation, Neuroinflammation, Neuronal Hyperexcitability, and Motor Coordination Deficits 

  Carrascal Moreno, María Livia; Vázquez Carretero, María Dolores; García Miranda, Pablo; Fontán Lozano, Ángela del Carmen; Calonge Castrillo, María Luisa; Ilundáin Larrañeta, María Anunciación Ana; Castro, Carmen; Núñez Abades, Pedro Antonio; Peral Rubio, María José (Multidisciplinary Digital Publishing Institute (MDPI), 2022)

  Neuroinflammation underlies neurodegenerative diseases. Herein, we test whether acute colon inflammation activates microglia ...

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  A Single Intraventricular Injection of VEGF Leads to Long-Term Neurotrophic Effects in Axotomized Motoneurons 

  Martín Calvo, Paula; Rodríguez de la Cruz, Rosa María; Pastor Loro, Ángel Manuel (Society for Neuroscience, 2020)

  Vascular endothelial growth factor (VEGF) has been recently demonstrated to induce neuroprotective and synaptotrophic ...

• Article
  

  Increased novelty-induced locomotion, sensitivity to amphetamine, and extracellular dopamine in striatum of Zdhhc15-deficient mice 

  Mejías Estévez, Rebeca María; Rodríguez Gotor, Juan J.; Niwa, Minae; Krasnova, Irina N.; Adamczyk, Abby; Han, Mei; Wang, Tao (Springer Nature, 2021)

  Novelty-seeking behaviors and impulsivity are personality traits associated with several psychiatric illnesses including ...

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  Evaluation of aquaporins in the cerebrospinal fluid in patients with idiopathic normal pressure hydrocephalus 

  Hiraldo González, Laura; Trillo Contreras, José Luis; García Miranda, Pablo; Pineda Sánchez, Rocío; Ramírez Lorca, Reposo; Rodrigo Herrero, Silvia; Olivares Blanco, Magdalena; Oliver, María; Bernal, María; Franco Macías, Emilio; Villadiego Luque, Francisco Javier; Echevarría Irusta, Miriam (PLOS, 2021)

  Brain aquaporin 1 (AQP1) and AQP4 are involved in cerebrospinal fluid (CSF) homeostasis and might participate in the origin ...

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  The Neurokinin-1 Receptor Is Essential for the Viability of Human Glioma Cells: A Possible Target for Treating Glioblastoma 

  Muñoz Pinto, Mario Faustino; Argüelles Castilla, Sandro; Rosso, Marisa; Medina, Rafael; Coveñas, Rafael; Ayala Gómez, Antonio; Muñoz, Miguel (Hindawi, 2022)

  Background. Glioblastoma or glioma is the most common malignant brain tumor. Patients have a prognosis of approximately ...

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  Palisade endings have an exocytotic machinery but lack acetylcholine receptors and distinct acetylcholinesterase activity 

  Blumer, Roland; Streicher, Johannes; Carrero Rojas, Génova; Martín Calvo, Paula; Rodríguez de la Cruz, Rosa María; Pastor Loro, Ángel Manuel (ARVO, 2020)

  Purpose: The purpose of this work was to test whether palisade endings express structural and molecular features of ...

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