dc.creator | Matador Martínez, Esteban | es |
dc.creator | de Gracia Retamosa, María | es |
dc.creator | Monge Fernández, David | es |
dc.creator | Iglesias Sigüenza, Francisco Javier | es |
dc.creator | Fernández Fernández, Rosario Fátima | es |
dc.creator | Lassaletta, José M. | es |
dc.date.accessioned | 2022-12-16T17:53:48Z | |
dc.date.available | 2022-12-16T17:53:48Z | |
dc.date.issued | 2018 | |
dc.identifier.citation | Matador Martínez, E., de Gracia Retamosa, M., Monge Fernández, D., Iglesias Sigüenza, F.J., Fernández Fernández, R.F. y Lassaletta, J.M. (2018). Bifunctional Squaramide Organocatalysts for the Asymmetric Addition of Formaldehyde tert-Butylhydrazone to Simple Aldehydes. Chemistry - A European Journal, 24 (26), 6854-6860. https://doi.org/10.1002/chem.201801052. | |
dc.identifier.issn | 0947-6539 | es |
dc.identifier.issn | 1521-3765 | es |
dc.identifier.uri | https://hdl.handle.net/11441/140587 | |
dc.description.abstract | The nucleophilic addition of formaldehyde tert-butylhydrazone to simple aldehydes (a formal hetero-carbonyl–ene reaction) can be performed with good reactivity and excellent enantioselectivity by virtue of the dual hydrogen-bonding activation exerted by amide–squaramide organocatalysts. The resulting hydroxydiazenes (azo alcohols) were isolated in high yields as enantiomerically enriched azoxy compounds after a regioselective azo-to-azoxy transformation. Subsequent derivatization provides an entry to relevant amino alcohols, oxazolidinones, and derivatives thereof. | es |
dc.description.sponsorship | Ministerio de Economía y Competitividad CTQ2016-76908-C2-1-P, TQ2016-76908-C2-2-P | es |
dc.description.sponsorship | Junta de Andalucía 2012/FQM1078 | es |
dc.format | application/pdf | es |
dc.format.extent | 9 p. | es |
dc.language.iso | eng | es |
dc.publisher | Wiley-Blackwell | es |
dc.relation.ispartof | Chemistry - A European Journal, 24 (26), 6854-6860. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Hydrazones | es |
dc.subject | Hydrogen bonds | es |
dc.subject | Organocatalysis | es |
dc.subject | Solvent effects | es |
dc.subject | Squaramides | es |
dc.title | Bifunctional Squaramide Organocatalysts for the Asymmetric Addition of Formaldehyde tert-Butylhydrazone to Simple Aldehydes | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/acceptedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Química orgánica | es |
dc.relation.projectID | CTQ2016-76908-C2-1-P | es |
dc.relation.projectID | TQ2016-76908-C2-2-P | es |
dc.relation.projectID | 2012/FQM1078 | es |
dc.relation.publisherversion | https://dx.doi.org/10.1002/chem.201801052 | es |
dc.identifier.doi | 10.1002/chem.201801052 | es |
dc.journaltitle | Chemistry - A European Journal | es |
dc.publication.volumen | 24 | es |
dc.publication.issue | 26 | es |
dc.publication.initialPage | 6854 | es |
dc.publication.endPage | 6860 | es |
dc.contributor.funder | Ministerio de Economía y Competitividad (MINECO). España | es |
dc.contributor.funder | Junta de Andalucía | es |
dc.description.awardwinning | Premio Mensual Publicación Científica Destacada de la US. Facultad de Química | |