dc.creator | de Gracia Retamosa, María | es |
dc.creator | Álvarez Casao, Yolanda | es |
dc.creator | Matador Martínez, Esteban | es |
dc.creator | Gómez, Ángela | es |
dc.creator | Monge Fernández, David | es |
dc.creator | Fernández Fernández, Rosario Fátima | es |
dc.creator | Lassaletta, José M. | es |
dc.date.accessioned | 2022-12-15T17:31:08Z | |
dc.date.available | 2022-12-15T17:31:08Z | |
dc.date.issued | 2019 | |
dc.identifier.citation | de Gracia Retamosa, M., Álvarez Casao, Y., Matador Martínez, E., Gómez, Á., Monge Fernández, D., Fernández Fernández, R.F. y Lassaletta, J.M. (2019). Pyridine-Hydrazone Ligands in Asymmetric Palladium-Catalyzed 1,4- and 1,6-Additions of Arylboronic Acids to Cyclic (Di)enones. Advanced Synthesis and Catalysis, 361 (1), 176-184. https://doi.org/10.1002/adsc.201801021. | |
dc.identifier.issn | 1615-4150 | es |
dc.identifier.issn | 1615-4169 | es |
dc.identifier.uri | https://hdl.handle.net/11441/140540 | |
dc.description.abstract | Catalysts generated by combinations of Pd(TFA)2 and enantiomerically pure pyridine-hydrazone ligands have been applied to the 1,4-addition of arylboronic acids to β-substituted cyclic enones, building all-carbon quaternary stereocenters in high yields and enantioselectivities (up to 93% ee). The developed methodology allows the efficient introduction of ortho-substituted aryl groups in β-position of cyclopentanone cores, giving scaffolds present in a broad range of biologically active natural products. These Pd(II)-complexes served also as catalysts in the 1,6-addition of arylboronic acids to cyclic dienones, affording complete regioselectivities, moderate yields and good enantioselectivities (up to 80% ee). | es |
dc.description.sponsorship | Ministerio de Asuntos Económicos y Transformación Digital CTQ2016-76908-C2-1-P, CTQ2016-76908-C2-2-P | es |
dc.description.sponsorship | Junta de Andalucía 2012/FQM1078 | es |
dc.format | application/pdf | es |
dc.format.extent | 9 p. | es |
dc.language.iso | eng | es |
dc.publisher | Wiley-Blackwell | es |
dc.relation.ispartof | Advanced Synthesis and Catalysis, 361 (1), 176-184. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Arylboronic acids | es |
dc.subject | Asymmetric Catalysis | es |
dc.subject | Hydrazones | es |
dc.subject | N Ligands | es |
dc.subject | Palladium | es |
dc.title | Pyridine-Hydrazone Ligands in Asymmetric Palladium-Catalyzed 1,4- and 1,6-Additions of Arylboronic Acids to Cyclic (Di)enones | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/acceptedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Química orgánica | es |
dc.relation.projectID | CTQ2016-76908-C2-2-P | es |
dc.relation.projectID | CTQ2016-76908-C2-1-P | es |
dc.relation.projectID | 2012/FQM1078 | es |
dc.relation.publisherversion | https://doi.org/10.1002/adsc.201801021 | es |
dc.identifier.doi | 10.1002/adsc.201801021 | es |
dc.journaltitle | Advanced Synthesis and Catalysis | es |
dc.publication.volumen | 361 | es |
dc.publication.issue | 1 | es |
dc.publication.initialPage | 176 | es |
dc.publication.endPage | 184 | es |
dc.contributor.funder | Ministerio de Asuntos Económicos y Transformación Digital (MINECO). España | es |
dc.contributor.funder | Junta de Andalucía | es |