dc.creator | López López, Óscar | es |
dc.creator | Padrón, José M. | es |
dc.date.accessioned | 2022-03-17T15:26:22Z | |
dc.date.available | 2022-03-17T15:26:22Z | |
dc.date.issued | 2022 | |
dc.identifier.citation | López López, Ó. y Padrón, J.M. (2022). Iridium-and Palladium-Based Catalysts in the Pharmaceutical Industry. Catalysts, 12 (2), 164. | |
dc.identifier.issn | 2073-4344 | es |
dc.identifier.uri | https://hdl.handle.net/11441/130967 | |
dc.description.abstract | Transition metal catalysts play a vital role in a wide range of industrial organic processes. The large-scale production of chemicals relying on catalyzed organic reactions represents a sustainable approach to supply society with end products for many daily life applications. Homogeneous (mainly for academic uses) and heterogeneous (crucial in industrial processes) metal-based catalysts have been developed for a plethora of organic reactions. The search for more sustainable strategies has led to the development of a countless number of metal-supported catalysts, nanosystems, and electrochemical and photochemical catalysts. In this work, although a vast number of transition metals can be used in this context, special attention is devoted to Ir-and Pd-based catalysts in the industrial manufacture of pharmaceutical drugs. Pd is by far the most widely used and versatile catalyst not only in academia but also in industry. Moreover, Ir-based complexes have emerged as attractive catalysts, particularly in asymmetric hydrogenation reactions. Ir-and Pd-based asymmetric reductions, aminations, cross-coupling reactions, and C–H activation are covered herein in the production of biologically active compounds or precursors; adaptation to bulk conditions is particularly highlighted. | es |
dc.description.sponsorship | Gobierno de Canarias SD-19/02 | es |
dc.description.sponsorship | Ministerio de Ciencia e Innovación PID2020-116460RB-I00, 10.13039/501100011033 | es |
dc.format | application/pdf | es |
dc.format.extent | 11 p. | es |
dc.language.iso | eng | es |
dc.publisher | Multidisciplinary Digital Publishing Institute (MDPI) | es |
dc.relation.ispartof | Catalysts, 12 (2), 164. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Catalysis | es |
dc.subject | Fine chemicals | es |
dc.subject | Scale-up | es |
dc.subject | Transition metals | es |
dc.title | Iridium-and Palladium-Based Catalysts in the Pharmaceutical Industry | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Química orgánica | es |
dc.relation.projectID | SD-19/02 | es |
dc.relation.projectID | PID2020-116460RB-I00 | es |
dc.relation.projectID | 10.13039/501100011033 | es |
dc.relation.publisherversion | https://doi.org/10.3390/catal12020164 | es |
dc.identifier.doi | 10.3390/catal12020164 | es |
dc.journaltitle | Catalysts | es |
dc.publication.volumen | 12 | es |
dc.publication.issue | 2 | es |
dc.publication.initialPage | 164 | es |