dc.creator | Hammouche Mokrane, Nawal | es |
dc.creator | León González, Antonio José | es |
dc.creator | Navarro Zafra, Inmaculada | es |
dc.creator | Boulila, Farida | es |
dc.creator | Benallaoua, Said | es |
dc.creator | Martín Cordero, Carmen | es |
dc.date.accessioned | 2022-01-12T13:31:20Z | |
dc.date.available | 2022-01-12T13:31:20Z | |
dc.date.issued | 2017 | |
dc.identifier.citation | Hammouche Mokrane, N., León González, A.J., Navarro Zafra, I., Boulila, F., Benallaoua, S. y Martín Cordero, C. (2017). Phytochemical Profile and Antibacterial Activity of Retama raetam and R. sphaerocarpa cladodes from Algeria. Natural Product Communications, 12 (12), 1857-1860. | |
dc.identifier.issn | 1934-578X | es |
dc.identifier.issn | 1555-9475 | es |
dc.identifier.uri | https://hdl.handle.net/11441/128789 | |
dc.description.abstract | Retama raetam (RR) and R. sphaerocarpa (RS) are shrubs growing in Algeria desert areas, where are commonly used as healing remedies because of their
antiseptic, antipyretic and anti-diarrheal properties. Phytochemical studies have shown that these species are very rich in flavonoids (isoflavones) and alkaloids
(quinolizidine and bipiperidyl). The aim of this study was to compare the chemical composition of both Retama species by GC/MS and LC/MS and to
determinate their antimicrobial activity of two Retama species growing naturally in Algeria. Ten alkaloids and seven flavonoids were identified in cladodes of
RR and RS. The quantitative analysis showed that the most abundant flavonoid of both the aqueous extract from RR and RS was the isoflavone genistein
(610.0±2.8 and 408.0±14.1 mg/100 g respectively), whereas sparteine was the predominant alkaloid in RR and retamine in RS. The antibacterial activity of
Retama extracts against standard strains was performed by minimum inhibitory concentration (MIC), and by the disc diffusion method (expressed by inhibition
zone, IZ). Both Retama species showed the best activity against Staphylococcus aureus and methicillin-resistant S. aureus (MRSA), being RS aqueous extract
more active than RR aqueous extract, with MIC 125 µg/mL and bactericidal activity against both strains. | es |
dc.format | application/pdf | es |
dc.format.extent | 4 p. | es |
dc.language.iso | eng | es |
dc.publisher | SAGE Publications | es |
dc.relation.ispartof | Natural Product Communications, 12 (12), 1857-1860. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Retama raetam | es |
dc.subject | Retama sphaerocarpa | es |
dc.subject | Quinolizidine alkaloids | es |
dc.subject | Isoflavonoids | es |
dc.subject | Antibacterial activit | es |
dc.title | Phytochemical Profile and Antibacterial Activity of Retama raetam and R. sphaerocarpa cladodes from Algeria | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Farmacología | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Química Física | es |
dc.relation.publisherversion | https://journals.sagepub.com/doi/pdf/10.1177/1934578X1701201211 | es |
dc.identifier.doi | 10.1177/1934578X1701201211 | es |
dc.journaltitle | Natural Product Communications | es |
dc.publication.volumen | 12 | es |
dc.publication.issue | 12 | es |
dc.publication.initialPage | 1857 | es |
dc.publication.endPage | 1860 | es |