dc.creator | Treviño, Ana | es |
dc.creator | Aguilera, Antonio | es |
dc.creator | Caballero, Estrella | es |
dc.creator | Benito, Rafael | es |
dc.creator | Parra, Patricia | es |
dc.creator | Eiros, Jose M | es |
dc.creator | Calderón Sandubete, Enrique José | es |
dc.creator | Soriano, Vicente | es |
dc.date.accessioned | 2021-07-07T14:52:54Z | |
dc.date.available | 2021-07-07T14:52:54Z | |
dc.date.issued | 2012 | |
dc.identifier.citation | Treviño, A., Aguilera, A., Caballero, E., Benito, R., Parra, P., Eiros, J.M.,...,Soriano, V. (2012). Trends in the prevalence and distribution of HTLV-1 and HTLV-2 infections in Spain. Virology Journal, 9 (71), 1-5. | |
dc.identifier.issn | 1743-422X (electrónico) | es |
dc.identifier.uri | https://hdl.handle.net/11441/115333 | |
dc.description.abstract | Background
Although most HTLV infections in Spain have been found in native intravenous drug users carrying HTLV-2, the large immigration flows from Latin America and Sub-Saharan Africa in recent years may have changed the prevalence and distribution of HTLV-1 and HTLV-2 infections, and hypothetically open the opportunity for introducing HTLV-3 or HTLV-4 in Spain. To assess the current seroprevalence of HTLV infection in Spain a national multicenter, cross-sectional, study was conducted in June 2009.
Results
A total of 6,460 consecutive outpatients attending 16 hospitals were examined. Overall, 12% were immigrants, and their main origin was Latin America (4.9%), Africa (3.6%) and other European countries (2.8%). Nine individuals were seroreactive for HTLV antibodies (overall prevalence, 0.14%). Evidence of HTLV-1 infection was confirmed by Western blot in 4 subjects (prevalence 0.06%) while HTLV-2 infection was found in 5 (prevalence 0.08%). Infection with HTLV types 1, 2, 3 and 4 was discarded by Western blot and specific PCR assays in another two specimens initially reactive in the enzyme immunoassay. All but one HTLV-1 cases were Latin-Americans while all persons with HTLV-2 infection were native Spaniards.
Conclusions
The overall prevalence of HTLV infections in Spain remains low, with no evidence of HTLV-3 or HTLV-4 infections so far. | es |
dc.description.sponsorship | FIS (CP05/00300) | es |
dc.description.sponsorship | FIPSE (36742/08) | es |
dc.description.sponsorship | Fundación Investigación y Educación en Sida (IES) | es |
dc.description.sponsorship | RIS (Red de Investigación en SIDA, ISCIII-RETIC RD06/006) | es |
dc.description.sponsorship | European NEAT project (LSHP-CT-2006-037570) | es |
dc.format | application/pdf | es |
dc.format.extent | 5 p. | es |
dc.language.iso | eng | es |
dc.publisher | BMC | es |
dc.relation.ispartof | Virology Journal, 9 (71), 1-5. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | HTLV | es |
dc.subject | Spain | es |
dc.subject | Seroprevalence | es |
dc.subject | Epidemiology | es |
dc.subject | HTLV-3 | es |
dc.subject | HTLV-4 | es |
dc.title | Trends in the prevalence and distribution of HTLV-1 and HTLV-2 infections in Spain | es |
dc.type | info:eu-repo/semantics/article | es |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Medicina | es |
dc.relation.projectID | CP05/00300 | es |
dc.relation.projectID | 36742/08 | es |
dc.relation.projectID | ISCIII-RETIC RD06/006 | es |
dc.relation.projectID | LSHP-CT-2006-037570 | es |
dc.relation.publisherversion | https://virologyj.biomedcentral.com/articles/10.1186/1743-422X-9-71 | es |
dc.identifier.doi | 10.1186/1743-422X-9-71 | es |
dc.journaltitle | Virology Journal | es |
dc.publication.volumen | 9 | es |
dc.publication.issue | 71 | es |
dc.publication.initialPage | 1 | es |
dc.publication.endPage | 5 | es |