Instituto de Biomedicina de Sevilla (IBIS)
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Artículo
The novel combination of sirolimus and bortezomib prevents graft-versus-host disease but maintains the graft-versus-leukemia effect after allogeneic transplantation
(Ferrata Storti Foundation, 2012)Background We have previously shown that bortezomib induces a depletion of alloreactive T cells and allows the expansion ...
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Reduced intensity conditioning increases risk of severe cGVHD: identification of risk factors for cGVHD in a multicenter setting
(Springer, 2018)Chronic graft-versus-host disease (cGVHD) remains a major cause of morbidity and mortality after allogeneic hematopoietic ...
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Survival Outcomes and Health-Related Quality of Life in Older Adults Diagnosed with Acute Myeloid Leukemia Receiving Frontline Therapy in Daily Practice
(MPDI, 2023-11-28)Acute myeloid leukemia has a poor prognosis in older adults, and its management is often unclear due to its underrepresentation ...
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Impact of disease burden and late loss of B cell aplasia on the risk of relapse after CD19 chimeric antigen receptor T Cell (Tisagenlecleucel) infusion in pediatric and young adult patients with relapse/refractory acute lymphoblastic leukemia: role of B-cell monitoring
(Frontiers Media S.A., 2024-01-16)Introduction: Loss of B-cell aplasia (BCA) is a well-known marker of functional loss of CD19 CAR-T. Most relapses and ...
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Hematological Neoplasms with Eosinophilia
(MDPI, 2024-01-12)The diagnostic assessment of eosinophilias is complex, requiring a multidisciplinary approach and often involving diagnostic ...
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Cannabinoids induce cell death in leukaemic cells through Parthanatos and PARP-related metabolic disruptions
(Nature Publishing Group, 2024)BACKGROUND: Several studies have described a potential anti-tumour effect of cannabinoids (CNB). CNB receptor 2 (CB2) is ...
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The carotid body, a neurogenic niche in the adult peripheral nervous system
(Univ pisa, 2010)We have described a new population of adult neural stem cells residing in the carotid body, a chemoreceptor organ in the ...
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Capítulo de Libro
A pathophysiological view of the neural stem cell niche
(Nova Science Publishers, INC. U.S., 2011)Neural stem cells were described in the nervous system some decades ago as being responsible for adult neurogenesis and ...
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Heteroleptic (S^C)-cyclometallated gold(III) complexes as novel antiviral agents
(Elsevier, 2024-03)Despite the increasingly widespread clinical impact of adenovirus (HAdV) infections in healthy individuals and the ...
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Online pain neuroscience education and graded exposure to movement in breast cancer survivors: protocol of a randomized controlled trial
(2024-02-24)Introduction: Cancer-related chronic pain is an important sequelae that damages the quality of life of breast cancer ...
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Inhibition of adenovirus transport from the endosome to the cell nucleus by rotenone
(Frontiers Media S.A., 2024-01-24)Regardless of the clinical impact of human adenovirus (HAdV) infections in the healthy population and its high morbidity ...
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Associations between Preoperative Patient Socioeconomic Status and Pain-Related Outcomes with Pain and Function in Patients Undergoing Rotator Cuff Repairs
(MDPI, 2023-10-21)BACKGROUND: Patients undergoing rotator cuff repairs commonly experience postoperative pain and functional limitations. ...
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Feasibility of the implementation of LESS-CHRON in clinical practice: a pilot intervention study in older patients with multimorbidity
(Oxford Academic, 2023)Background and Objectives: Potentially inappropriate medication refers to the prescription of drugs whose risks outweigh ...
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Risk factors for infections caused by carbapenem-resistant Enterobacterales: an international matched case-control-control study (EURECA)
(2023)Background Data on risk factors for carbapenem-resistant Enterobacterales (CRE) with wider applicability are needed to ...
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Artículo
TARTESSUS: a customized electrospun drug delivery system loaded with irinotecan for local and sustained chemotherapy release in pancreatic cancer
(MDPI, 2023)Post-surgical chemotherapy in pancreatic cancer has notorious side effects due to the high dose required. Multiple devices ...
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Sex differences in motor and non-motor symptoms among Spanish patients with Parkinson’s disease
(MDPI, 2023)Background and objective: Sex plays a role in Parkinson’s disease (PD) mechanisms. We analyzed sex difference manifestations ...
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The essential role of IL-17 as the pathogenetic link between psoriasis and metabolic-associated fatty liver disease
(MDPI, 2023)Interleukin 17 (IL-17) is an effector cytokine that plays a key role in the pathogenesis of both psoriasis and ...
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Polygenic risk score-based phenome-wide association study identifies novel associations for Tourette syndrome
(Nature Publishing Group, 2023)Tourette Syndrome (TS) is a complex neurodevelopmental disorder characterized by vocal and motor tics lasting more than a ...
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VE-Cadherin modulates β-catenin/TCF-4 to enhance vasculogenic mimicry
(Nature Publishing Group, 2023)Vasculogenic Mimicry (VM) refers to the capacity to form a blood network from aggressive cancer cells in an independent ...
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Detection of high level of co-infection and the emergence of novel SARS CoV-2 delta-omicron and omicron-omicron recombinants in the epidemiological surveillance of Andalusia
(MDPI, 2023)Recombination is an evolutionary strategy to quickly acquire new viral properties inherited from the parental lineages. ...